Search Results - "Robert A. Kozak"
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Isolation, Sequence, Infectivity, and Replication Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2
Published in Emerging infectious diseases (01-09-2020)“…Since its emergence in Wuhan, China, in December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected ≈6 million persons worldwide…”
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Real-time PCR-based SARS-CoV-2 detection in Canadian laboratories
Published in Journal of clinical virology (01-07-2020)“…With emergence of pandemic COVID-19, rapid and accurate diagnostic testing is essential. This study compared laboratory-developed tests (LDTs) used for the…”
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Altered microRNA Transcriptome in Cultured Human Airway Cells upon Infection with SARS-CoV-2
Published in Viruses (01-02-2023)“…Numerous proteomic and transcriptomic studies have been carried out to better understand the current multi-variant SARS-CoV-2 virus mechanisms of action and…”
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A Comparison of Whole Genome Sequencing of SARS-CoV-2 Using Amplicon-Based Sequencing, Random Hexamers, and Bait Capture
Published in Viruses (15-08-2020)“…Genome sequencing of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is increasingly important to monitor the transmission and adaptive evolution…”
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Contribution of a mutational bias in hepatitis C virus replication to the genetic barrier in the development of drug resistance
Published in Proceedings of the National Academy of Sciences - PNAS (20-12-2011)“…The development of resistance to direct-acting antivirals (DAAs) targeting the hepatitis C virus (HCV) can compromise therapy. However, mechanisms that…”
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Ebola Virus Encodes Two microRNAs in Huh7-Infected Cells
Published in International journal of molecular sciences (07-05-2022)“…MicroRNAs (miRNAs) are important gene regulatory molecules involved in a broad range of cellular activities. Although the existence and functions of miRNAs are…”
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Shifts in Mapuche Food Systems in Southern Andean Forest Landscapes: Historical Processes and Current Trends of Biocultural Homogenization
Published in Mountain research and development (01-02-2019)“…Mountain communities that use local foods are more likely to be food secure over time. However, historical and contemporary policies have largely homogenized…”
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Next generation sequencing of the hepatitis C virus NS5B gene reveals potential novel S282 drug resistance mutations
Published in Virology (New York, N.Y.) (01-03-2015)“…Abstract Identifying HCV drug resistance mutations (DRMs) is increasingly important as new direct acting antiviral therapies (DAA) become available. Tagged…”
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MicroRNA and mRNA Dysregulation in Astrocytes Infected with Zika Virus
Published in Viruses (14-10-2017)“…The Zika virus (ZIKV) epidemic is an ongoing public health concern. ZIKV is a flavivirus reported to be associated with microcephaly, and recent work in animal…”
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Molecular characterization of pathogenic and nonpathogenic fowl aviadenovirus serotype 11 isolates
Published in Canadian journal of microbiology (01-12-2016)“…Fowl aviadenoviruses, many of which are of importance in veterinary medicine, are classified into 5 species. In this study, a pathogenic isolate and a…”
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Development and Evaluation of a Molecular Hepatitis A Virus Assay for Serum and Stool Specimens
Published in Viruses (15-01-2022)“…Hepatitis A virus (HAV) is an emerging public health concern and there is an urgent need for ways to rapidly identify cases so that outbreaks can be managed…”
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Nosocomial outbreak of vanD-carrying vancomycin-resistant Enterococcus faecium
Published in Infection control and hospital epidemiology (01-10-2018)“…Multilocus sequence typing of 7 housekeeping genes (adk, atpA, ddI, gdh, gyd, purK, and pstD) demonstrated a complete match with sequence type 117 (ST117) in…”
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Dual RNA-Seq characterization of host and pathogen gene expression in liver cells infected with Crimean-Congo Hemorrhagic Fever Virus
Published in PLoS neglected tropical diseases (01-04-2020)“…Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne virus that can cause a hemorrhagic fever in humans, with a case fatality rate of up to 40%. Cases…”
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Characterization of a novel adenovirus isolated from a skunk
Published in Virology (New York, N.Y.) (01-11-2015)“…Abstract Adenoviruses are a ubiquitous group of viruses that have been found in a wide range of hosts. A novel adenovirus from a skunk suffering from acute…”
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Hepatitis C Core-Antigen Testing from Dried Blood Spots
Published in Viruses (06-09-2019)“…In order to expand hepatitis C virus (HCV) screening, a change in the diagnostic paradigm is warranted to improve accessibility and decrease costs, such as…”
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Participatory landscape planning and sustainable community development: Methodological observations from a case study in rural Mexico
Published in Landscape and urban planning (15-01-2010)“…Most local authorities in rural Mexico lack relevant resource data at appropriate scales to develop community plans, even though planning and development…”
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Differential Gene Expression in the Upper Respiratory Tract following Acute COVID-19 Infection in Ambulatory Patients That Develop Long COVID
Published in Pathogens (Basel) (17-06-2024)“…Post-acute sequelae of COVID-19, or long COVID, is a condition characterized by persistent COVID-19 symptoms. As long COVID is defined by clinical criteria…”
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Presence of Flavivirus Antibodies Does Not Lead to a Greater Number of Symptoms in a Small Cohort of Canadian Travelers Infected with Zika Virus
Published in Viruses (24-01-2020)“…Zika virus (ZIKV) is a mosquito-borne flavivirus associated with a febrile illness as well as severe complications, including microcephaly and Guillain-Barré…”
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Streptococcus pyogenes secondary impetigo due to loofah sponge use
Published in IDCases (01-01-2022)“…•Loofah sponges are used for skin cleaning, but can become contaminated with bacterial pathogens•The abrasive nature of loofah sponges can allow for bacteria…”
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Replication and Oncolytic Activity of an Avian Orthoreovirus in Human Hepatocellular Carcinoma Cells
Published in Viruses (24-04-2017)“…Oncolytic viruses are cancer therapeutics with promising outcomes in pre-clinical and clinical settings. Animal viruses have the possibility to avoid…”
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