Search Results - "Robert, Stephanie M."

Disruption of astrocyte–vascular coupling and the blood–brain barrier by invading glioma cells by Watkins, Stacey, Robel, Stefanie, Kimbrough, Ian F., Robert, Stephanie M., Ellis-Davies, Graham, Sontheimer, Harald

“…Astrocytic endfeet cover the entire cerebral vasculature and serve as exchange sites for ions, metabolites and energy substrates from the blood to the brain…”
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Glutamate transporters in the biology of malignant gliomas by Robert, Stephanie M, Sontheimer, Harald

“…Malignant gliomas are relentless tumors that offer a dismal clinical prognosis. They develop many biological advantages that allow them to grow and survive in…”
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Surgical strategies for intracranial meningioma in the molecular era by Dincer, Alper, Morales-Valero, Saul F., Robert, Stephanie M., Tabor, Joanna K., O’Brien, Joseph, Yalcin, Kanat, Fulbright, Robert K., Erson-Omay, Zeynep, Dunn, Ian F., Moliterno, Jennifer

“…Introduction Surgical resection has long been the treatment of choice for meningiomas and is considered curative in many cases. Indeed, the extent of resection…”
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Commentary: Feasibility and Morbidity of Magnetic Resonance Imaging-Guided Stereotactic Laser Ablation of Deep Cerebral Cavernous Malformations: A Report of 4 Cases by Robert, Stephanie M, Chiang, Veronica L

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A proinvasive role for the Ca2+-activated K+ channel KCa3.1 in malignant glioma by Turner, Kathryn L., Honasoge, Avinash, Robert, Stephanie M., McFerrin, Michael M., Sontheimer, Harald

“…Main Points Using the NCI database, we found that upregulation of KCa3.1 correlates with poor prognosis in patients. Pharmacological inhibition or genetic…”
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SLC7A11 expression is associated with seizures and predicts poor survival in patients with malignant glioma by Robert, Stephanie M, Buckingham, Susan C, Campbell, Susan L, Robel, Stefanie, Holt, Kenneth T, Ogunrinu-Babarinde, Toyin, Warren, Paula P, White, David M, Reid, Meredith A, Eschbacher, Jenny M, Berens, Michael E, Lahti, Adrienne C, Nabors, Louis B, Sontheimer, Harald

“…Glioma is the most common malignant primary brain tumor. Its rapid growth is aided by tumor-mediated glutamate release, creating peritumoral excitotoxic cell…”
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A proinvasive role for the Ca(2+) -activated K(+) channel KCa3.1 in malignant glioma by Turner, Kathryn L, Honasoge, Avinash, Robert, Stephanie M, McFerrin, Michael M, Sontheimer, Harald

“…Glioblastoma multiforme are highly motile primary brain tumors. Diffuse tissue invasion hampers surgical resection leading to poor patient prognosis. Recent…”
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A neural stem cell paradigm of pediatric hydrocephalus by Duy, Phan Q, Rakic, Pasko, Alper, Seth L, Robert, Stephanie M, Kundishora, Adam J, Butler, William E, Walsh, Christopher A, Sestan, Nenad, Geschwind, Daniel H, Jin, Sheng Chih, Kahle, Kristopher T

“…Abstract Pediatric hydrocephalus, the leading reason for brain surgery in children, is characterized by enlargement of the cerebral ventricles classically…”
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The choroid plexus links innate immunity to CSF dysregulation in hydrocephalus by Robert, Stephanie M., Reeves, Benjamin C., Kiziltug, Emre, Duy, Phan Q., Karimy, Jason K., Mansuri, M. Shahid, Marlier, Arnaud, Allington, Garrett, Greenberg, Ana B.W., DeSpenza, Tyrone, Singh, Amrita K., Zeng, Xue, Mekbib, Kedous Y., Kundishora, Adam J., Nelson-Williams, Carol, Hao, Le Thi, Zhang, Jinwei, Lam, TuKiet T., Wilson, Rashaun, Butler, William E., Diluna, Michael L., Feinberg, Philip, Schafer, Dorothy P., Movahedi, Kiavash, Tannenbaum, Allen, Koundal, Sunil, Chen, Xinan, Benveniste, Helene, Limbrick, David D., Schiff, Steven J., Carter, Bob S., Gunel, Murat, Simard, J. Marc, Lifton, Richard P., Alper, Seth L., Delpire, Eric, Kahle, Kristopher T.

“…The choroid plexus (ChP) is the blood-cerebrospinal fluid (CSF) barrier and the primary source of CSF. Acquired hydrocephalus, caused by brain infection or…”
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Contribution of Somatic Ras/Raf/Mitogen-Activated Protein Kinase Variants in the Hippocampus in Drug-Resistant Mesial Temporal Lobe Epilepsy by Khoshkhoo, Sattar, Wang, Yilan, Chahine, Yasmine, Erson-Omay, E Zeynep, Robert, Stephanie M, Kiziltug, Emre, Damisah, Eyiyemisi C, Nelson-Williams, Carol, Zhu, Guangya, Kong, Wenna, Huang, August Yue, Stronge, Edward, Phillips, H Westley, Chhouk, Brian H, Bizzotto, Sara, Chen, Ming Hui, Adikari, Thiuni N, Ye, Zimeng, Witkowski, Tom, Lai, Dulcie, Lee, Nadine, Lokan, Julie, Scheffer, Ingrid E, Berkovic, Samuel F, Haider, Shozeb, Hildebrand, Michael S, Yang, Edward, Gunel, Murat, Lifton, Richard P, Richardson, R Mark, Blümcke, Ingmar, Alexandrescu, Sanda, Huttner, Anita, Heinzen, Erin L, Zhu, Jidong, Poduri, Annapurna, DeLanerolle, Nihal, Spencer, Dennis D, Lee, Eunjung Alice, Walsh, Christopher A, Kahle, Kristopher T

“…Mesial temporal lobe epilepsy (MTLE) is the most common focal epilepsy subtype and is often refractory to antiseizure medications. While most patients with…”
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New drugs on the horizon for cerebral edema: what's in the clinical development pipeline? by Robert, Stephanie M, Reeves, Benjamin C, Alper, Seth L, Zhang, Jinwei, Kahle, Kristopher T

“…Research has advanced our understanding of the molecular and cellular mechanisms of cerebral edema and has propelled the development of novel antiedema…”
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Role of glutamate transporters in redox homeostasis of the brain by Robert, Stephanie M., Ogunrinu-Babarinde, Toyin, Holt, Kenneth T., Sontheimer, Harald

“…•Redox homeostasis is important in the brain due to high O2 consumption and ROS production.•Glutathione is an important mediator of redox homeostasis in the…”
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The integrated multiomic diagnosis of sporadic meningiomas: a review of its clinical implications by Robert, Stephanie M., Vetsa, Shaurey, Nadar, Arushii, Vasandani, Sagar, Youngblood, Mark W., Gorelick, Evan, Jin, Lan, Marianayagam, Neelan, Erson-Omay, E Zeynep, Günel, Murat, Moliterno, Jennifer

“…Introduction Meningiomas are generally considered “benign,” however, these tumors can demonstrate variability in behavior and a surprising aggressiveness with…”
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Protein kinase D1 variant associated with human epilepsy and peripheral nerve hypermyelination by Omer, Salma, Jin, Sheng Chih, Koumangoye, Rainelli, Robert, Stephanie M., Duran, Daniel, Nelson‐Williams, Carol, Huttner, Anita, DiLuna, Michael, Kahle, Kristopher T., Delpire, Eric

“…We report the case of a patient with severe progressive epilepsy and peripheral neuropathy and a novel de novo inactivating variant (p.E79X) in Protein Kinase…”
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Inflammatory hydrocephalus by Robert, Stephanie M., Reeves, Benjamin C., Marlier, Arnaud, Duy, Phan Q., DeSpenza, Tyrone, Kundishora, Adam, Kiziltug, Emre, Singh, Amrita, Allington, Garrett, Alper, Seth L., Kahle, Kristopher T.

“…Reparative inflammation is an important protective response that eliminates foreign organisms, damaged cells, and physical irritants. However, inappropriately…”
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Associated risk factors for extended length of stay following anterior cervical discectomy and fusion for cervical spondylotic myelopathy by Elsamadicy, Aladine A., Koo, Andrew B., Lee, Megan, David, Wyatt B., Kundishora, Adam J., Robert, Stephanie M., Kuzmik, Gregory A., Coutinho, Pedro O., Kolb, Luis, Laurans, Maxwell, Abbed, Khalid

“…•Black or Hispanic race led to extended LOS.•Lower socioeconomic status led to extended LOS.•Patients with extended LOS had greater overall costs. There is a…”
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Correction to: The integrated multiomic diagnosis of sporadic meningiomas: a review of its clinical implications by Robert, Stephanie M., Vetsa, Shaurey, Nadar, Arushii, Vasandani, Sagar, Youngblood, Mark W., Gorelick, Evan, Jin, Lan, Marianayagam, Neelan, Erson-Omay, E Zeynep, Günel, Murat, Moliterno, Jennifer

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Genomic approaches to improve the clinical diagnosis and management of patients with congenital hydrocephalus by Allington, Garrett, Duy, Phan Q, Ryou, Jian, Singh, Amrita, Kiziltug, Emre, Robert, Stephanie M, Kundishora, Adam J, King, Spencer, Haider, Shozeb, Kahle, Kristopher T, Jin, Sheng Chih

“…Congenital hydrocephalus (CH), characterized by incomplete clearance of CSF and subsequent enlargement of brain ventricles, is the most common congenital brain…”
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Thirty- and 90-Day Readmissions After Treatment of Traumatic Subdural Hematoma: National Trend Analysis by Koo, Andrew B., Elsamadicy, Aladine A., David, Wyatt B., Zogg, Cheryl K., Santarosa, Corrado, Sujijantarat, Nanthiya, Robert, Stephanie M., Kundishora, Adam J., Cord, Branden J., Hebert, Ryan, Bahrassa, Farhad, Malhotra, Ajay, Matouk, Charles C.

“…Subdural hematoma (SDH), a form of traumatic brain injury, is a common disease that requires extensive patient management and resource utilization; however,…”
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Isolated unilateral alar ligamentous injury: illustrative cases by Reeves, Benjamin C, Valcarce-Aspegren, Marcus, Robert, Stephanie M, Elsamadicy, Aladine A, Tucker, Alexander M, Storm, Phillip B, DiLuna, Michael L, Kundishora, Adam J

“…Isolated unilateral alar ligament injury (IUALI) is a rare and likely underreported occurrence after upper cervical trauma, with only 16 cases documented in…”
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