Search Results - "Roberd M. Bostick"

A Serological Biopsy Using Five Stomach-Specific Circulating Biomarkers for Gastric Cancer Risk Assessment: A Multi-Phase Study by Tu, Huakang, Sun, Liping, Dong, Xiao, Gong, Yuehua, Xu, Qian, Jing, Jingjing, Bostick, Roberd M, Wu, Xifeng, Yuan, Yuan

“…We aimed to assess a serological biopsy using five stomach-specific circulating biomarkers-pepsinogen I (PGI), PGII, PGI/II ratio, anti-Helicobacter pylori (H…”
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Clinical trials of antioxidants as cancer prevention agents: Past, present, and future by Goodman, Michael, Bostick, Roberd M., Kucuk, Omer, Jones, Dean P.

“…The purpose of this review is to summarize the most important human clinical trials of antioxidants as cancer prevention agents conducted to date, provide an…”
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A Trial of Calcium and Vitamin D for the Prevention of Colorectal Adenomas by Baron, John A, Barry, Elizabeth L, Mott, Leila A, Rees, Judy R, Sandler, Robert S, Snover, Dale C, Bostick, Roberd M, Ivanova, Anastasia, Cole, Bernard F, Ahnen, Dennis J, Beck, Gerald J, Bresalier, Robert S, Burke, Carol A, Church, Timothy R, Cruz-Correa, Marcia, Figueiredo, Jane C, Goodman, Michael, Kim, Adam S, Robertson, Douglas J, Rothstein, Richard, Shaukat, Aasma, Seabrook, March E, Summers, Robert W

“…In this placebo-controlled trial involving patients with recently diagnosed adenomas, daily supplementation with vitamin D 3 (1000 IU), calcium (1200 mg), or…”
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Oxidative balance score as predictor of all-cause, cancer, and noncancer mortality in a biracial US cohort by Kong, So Yeon, PhD, MPH, Goodman, Michael, MD, MPH, Judd, Suzanne, PhD, MPH, Bostick, Roberd M., MD, MPH, Flanders, W. Dana, MD, DSc, McClellan, William, MD, MPH

“…Abstract Purpose We previously proposed an oxidative balance score (OBS) that combines pro- and anti-oxidant exposures to represent the overall oxidative…”
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Vitamin D Gene Pathway Polymorphisms and Risk of Colorectal, Breast, and Prostate Cancer by McCullough, Marjorie L, Bostick, Roberd M, Mayo, Tinisha L

“…Higher vitamin D exposure is hypothesized to prevent several cancers, possibly through genomic effects modulated by the vitamin D receptor (VDR), and…”
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Effects of supplemental vitamin D and calcium on markers of proliferation, differentiation, and apoptosis in the normal colorectal mucosa of colorectal adenoma patients by Gao, Yasheen, Um, Caroline Y, Fedirko, Veronika, Rutherford, Robin E, Seabrook, March E, Barry, Elizabeth L, Baron, John A, Bostick, Roberd M

“…To clarify the roles of vitamin D and calcium as potential chemopreventive agents against colorectal cancer in humans, and to develop "treatable",…”
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Effects of Supplemental Vitamin D and Calcium on Oxidative DNA Damage Marker in Normal Colorectal Mucosa: A Randomized Clinical Trial by FEDIRKO, Veronika, BOSTICK, Roberd M, QI LONG, DANA FLANDERS, W, MCCULLOUGH, Marjorie L, SIDELNIKOV, Eduard, DANIEL, Carrie R, RUTHERFORD, Robin E, SHAUKAT, Aasma

“…The exact antineoplastic effects of calcium and vitamin D 3 in the human colon are unclear. Animal and in vitro studies show that these two agents reduce…”
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Effects of calcium and vitamin D supplementation on blood pressure and serum lipids and carotenoids: a randomized, double-blind, placebo-controlled, clinical trial by Chai, Weiwen, PhD, Cooney, Robert V., PhD, Franke, Adrian A., PhD, Bostick, Roberd M., MD, MPH

“…Abstract Purpose To estimate the effects of calcium or vitamin D supplementation or a combination of both on blood pressure and serum lipid and carotenoid…”
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Effects of supplemental vitamin D and calcium on biomarkers of inflammation in colorectal adenoma patients: a randomized, controlled clinical trial by Hopkins, Myfanwy H, Owen, Joy, Ahearn, Thomas, Fedirko, Veronika, Flanders, W Dana, Jones, Dean P, Bostick, Roberd M

“…Vitamin D and calcium affect several pathways involved in inflammation, tumor growth, and immune surveillance relevant to carcinogenesis. Also, epidemiologic…”
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Lifestyle and Other Factors Explain One-Half of the Variability in the Serum 25-Hydroxyvitamin D Response to Cholecalciferol Supplementation in Healthy Adults by Rees, Judy R, Mott, Leila A, Barry, Elizabeth L, Baron, John A, Bostick, Roberd M, Figueiredo, Jane C, Bresalier, Robert S, Robertson, Douglas J, Peacock, Janet L

“…Many factors have been associated with serum 25-hydroxyvitamin D [25(OH)D] concentrations in observational studies, with variable consistency. However, less…”
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Effects of Vitamin D and Calcium on Proliferation and Differentiation In Normal Colon Mucosa: a Randomized Clinical Trial by FEDIRKO, Veronika, BOSTICK, Roberd M, DANA FLANDERS, W, QI LONG, SIDELNIKOV, Eduard, SHAUKAT, Aasma, DANIEL, Carrie R, RUTHERFORD, Robin E, JOELLE WOODARD, Jill

“…To investigate the potential efficacy of calcium and vitamin D in reducing risk for colorectal neoplasms and to develop “treatable” phenotypic biomarkers of…”
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Oxidative balance score and risk for incident prostate cancer in a prospective U.S. cohort study by Lakkur, Sindhu, PhD, Goodman, Michael, MD, Bostick, Roberd M., MD, Citronberg, Jessica, MPH, McClellan, William, MD, Flanders, William Dana, MD, Judd, Suzanne, PhD, Stevens, Victoria L., PhD

“…Abstract Purpose Oxidative stress is defined as an imbalance between pro-oxidants and antioxidants. Previous research found that a single comprehensive…”
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Antioxidant enzyme and DNA base repair genetic risk scores' associations with systemic oxidative stress biomarker in pooled cross-sectional studies by Mao, Ziling, Gray, Abigail L H, Thyagarajan, Bharat, Bostick, Roberd M

“…Oxidative stress is hypothesized to contribute to the pathogenesis of several chronic diseases. Numerous dietary and lifestyle factors are associated with…”
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Antioxidant Micronutrients and Biomarkers of Oxidative Stress and Inflammation in Colorectal Adenoma Patients: Results from a Randomized, Controlled Clinical Trial by HOPKINS, Myfanwy H, FEDIRKO, Veronika, JONES, Dean P, TERRY, Paul D, BOSTICK, Roberd M

“…Previous epidemiologic observational and experimental studies investigated the potential of antioxidant micronutrients to modulate cancer risk, but these…”
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Association of trainee participation with adenoma and polyp detection rates by Qayed, Emad, Shea, Lauren, Goebel, Stephan, Bostick, Roberd M

“…AIM To investigate whether adenoma and polyp detection rates(ADR and PDR, respectively) in screening colonoscopies performed in the presence of fellows differ…”
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Associations of DNA Base Excision Repair and Antioxidant Enzyme Genetic Risk Scores with Biomarker of Systemic Inflammation by Mao, Ziling, Gray, Abigail L. H., Gross, Myron D., Thyagarajan, Bharat, Bostick, Roberd M.

“…Background: Inflammation is implicated in the etiology of various aging-related diseases. Numerous dietary and lifestyle factors contribute to chronic systemic…”
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Effects of supplemental vitamin D and calcium on normal colon tissue and circulating biomarkers of risk for colorectal neoplasms by Bostick, Roberd M.

“…•Strong biological rationale for vitamin D and calcium in preventing colon cancer.•Biomarkers developed to help screen potential preventive…”
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Calcium supplementation increases blood creatinine concentration in a randomized controlled trial by Barry, Elizabeth L, Mott, Leila A, Melamed, Michal L, Rees, Judith R, Ivanova, Anastasia, Sandler, Robert S, Ahnen, Dennis J, Bresalier, Robert S, Summers, Robert W, Bostick, Roberd M, Baron, John A

“…Calcium supplements are widely used among older adults for osteoporosis prevention and treatment. However, their effect on creatinine levels and kidney…”
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Associations of dietary, lifestyle, other participant characteristics, and oxidative balance scores with plasma F2-isoprostanes concentrations in a pooled cross-sectional study by Mao, Ziling, Bostick, Roberd M.

“…Purpose Plasma F 2 -isoprostanes (FiP) concentration, a reliably measured, valid, systemic oxidative stress biomarker, has been associated with multiple…”
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TGF-α Expression as a Potential Biomarker of Risk Within the Normal-appearing Colorectal Mucosa of Patients with and without Incident Sporadic Adenoma by Daniel, Carrie R, Bostick, Roberd M, Flanders, William Dana, Long, Qi, Fedirko, Veronika, Sidelnikov, Eduard, Seabrook, March E

“…Background: Transforming growth factor-α (TGF-α), a stimulatory growth factor and member of the epidermal growth factor family, is a mediator of oncogenesis…”
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