Search Results - "Robbins, Jon"

Candidalysin is a fungal peptide toxin critical for mucosal infection by Moyes, David L., Wilson, Duncan, Richardson, Jonathan P., Mogavero, Selene, Tang, Shirley X., Wernecke, Julia, Höfs, Sarah, Gratacap, Remi L., Robbins, Jon, Runglall, Manohursingh, Murciano, Celia, Blagojevic, Mariana, Thavaraj, Selvam, Förster, Toni M., Hebecker, Betty, Kasper, Lydia, Vizcay, Gema, Iancu, Simona I., Kichik, Nessim, Häder, Antje, Kurzai, Oliver, Luo, Ting, Krüger, Thomas, Kniemeyer, Olaf, Cota, Ernesto, Bader, Oliver, Wheeler, Robert T., Gutsmann, Thomas, Hube, Bernhard, Naglik, Julian R.

“…Cytolytic proteins and peptide toxins are classical virulence factors of several bacterial pathogens which disrupt epithelial barrier function, damage cells…”
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Mechanisms of ATP- and glutamate-mediated calcium signaling in white matter astrocytes by Hamilton, Nicola, Vayro, Steven, Kirchhoff, Frank, Verkhratsky, Alexej, Robbins, Jon, Gorecki, Dariuz C., Butt, Arthur M.

“…Neurotransmitters released at synapses mediate Ca2+ signaling in astrocytes in CNS grey matter. Here, we show that ATP and glutamate evoke these Ca2+ signals…”
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Commercialisation of CMOS integrated circuit technology in multi-electrode arrays for neuroscience and cell-based biosensors by Graham, Anthony H D, Robbins, Jon, Bowen, Chris R, Taylor, John

“…The adaptation of standard integrated circuit (IC) technology as a transducer in cell-based biosensors in drug discovery pharmacology, neural interface systems…”
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Effects of KCNQ2 gene truncation on M-type Kv7 potassium currents by Robbins, Jon, Passmore, Gayle M, Abogadie, Fe C, Reilly, Joanne M, Brown, David A

“…The KCNQ2 gene product, Kv7.2, is a subunit of the M-channel, a low-threshold voltage-gated K(+) channel that regulates mammalian and human neuronal…”
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Modification of heterotrimeric G-proteins in Swiss 3T3 cells stimulated with Pasteurella multocida toxin by Babb, Rebecca C, Homer, Karen A, Robbins, Jon, Lax, Alistair J

“…Many bacterial toxins covalently modify components of eukaryotic signalling pathways in a highly specific manner, and can be used as powerful tools to decipher…”
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The Discovery and Characterization of a Proton-Gated Sodium Current in Rat Retinal Ganglion Cells by Lilley, Sarah, LeTissier, Paul, Robbins, Jon

“…The conduction of acid-evoked currents in central and sensory neurons is now primarily attributed to a family of proteins called acid-sensing ion channels…”
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Formation of a porous alumina electrode as a low-cost CMOS neuronal interface by Graham, Anthony H.D., Bowen, Chris R., Robbins, Jon, Taylor, John

“…A low-cost electrode design has been devised for drug discovery pharmacology, neural interface systems, cell-based biosensors and electrophysiology research,…”
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Protein kinase C bound with A-kinase anchoring protein is involved in muscarinic receptor-activated modulation of M-type KCNQ potassium channels by Higashida, Haruhiro, Hoshi, Naoto, Zhang, Jia-Sheng, Yokoyama, Shigeru, Hashii, Minako, Jin, Duo, Noda, Mami, Robbins, Jon

“…The second messenger for closure of M/KCNQ potassium channels in post-ganglionic neurons and central neurons had remained as a ‘mystery in the neuroscience…”
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Characterization of the anandamide induced depolarization of guinea‐pig isolated vagus nerve by Kagaya, Manabu, Lamb, Jasmine, Robbins, Jon, Page, Clive P, Spina, Domenico

“…There is considerable interest in elucidating potential endogenously derived agonists of the vanilloid receptor and the role of anandamide in this regard has…”
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Overexpression of human CD38/ADP-ribosyl cyclase enhances acetylcholine-induced Ca2+ signalling in rodent NG108-15 neuroblastoma cells by Higashida, Haruhiro, Bowden, Sarah E H, Yokoyama, Shigeru, Salmina, Alla, Hashii, Minako, Hoshi, Naoto, Zhang, Jia-Sheng, Knijnik, Rimma, Noda, Mami, Zhong, Zen-Guo, Jin, Duo, Higashida, Kazuhiro, Takeda, Hisashi, Akita, Tenpei, Kuba, Kenji, Yamagishi, Sayaka, Shimizu, Noriaki, Takasawa, Shin, Okamoto, Hiroshi, Robbins, Jon

“…The role of cyclic ADP-ribose (cADPR) and its synthetic enzyme, CD38, as a downstream signal of muscarinic acetylcholine receptors (mAChRs) was examined in…”
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Overexpression of human CD38/ADP-ribosyl cyclase enhances acetylcholine-induced Ca 2+ signalling in rodent NG108-15 neuroblastoma cells by Higashida, Haruhiro, Bowden, Sarah E.H., Yokoyama, Shigeru, Salmina, Alla, Hashii, Minako, Hoshi, Naoto, Zhang, Jia-Sheng, Knijnik, Rimma, Noda, Mami, Zhong, Zen-Guo, Jin, Duo, Higashida, Kazuhiro, Takeda, Hisashi, Akita, Tenpei, Kuba, Kenji, Yamagishi, Sayaka, Shimizu, Noriaki, Takasawa, Shin, Okamoto, Hiroshi, Robbins, Jon

“…The role of cyclic ADP-ribose (cADPR) and its synthetic enzyme, CD38, as a downstream signal of muscarinic acetylcholine receptors (mAChRs) was examined in…”
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The role of ryanodine receptors in the cyclic ADP ribose modulation of the M-like current in rodent m1 muscarinic receptor-transformed NG108-15 cells by Bowden, Sarah E. H., Selyanko, Alexander A., Robbins, Jon

“…The role of cyclic ADP ribose and ryanodine receptors in the inhibition of the M-like current ( I K(M,ng) ) by acetylcholine was investigated in m1 muscarinic…”
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KCNQ potassium channels: physiology, pathophysiology, and pharmacology by Robbins, Jon

“…KCNQ genes encode a growing family of six transmembrane domains, single pore-loop, K + channel α-subunits that have a wide range of physiological correlates…”
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Probing the Regulation of M (Kv7) Potassium Channels in Intact Neurons with Membrane-Targeted Peptides by Robbins, Jon, Marsh, Stephen J, Brown, David A

“…M-type (Kv7) potassium channels are closed by Gq/11 G-protein-coupled receptors. Several membrane- or channel-associated molecules have been suggested to…”
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Editorial by Robbins, Jon

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The actions of Pasteurella multocida toxin on neuronal cells by Surguy, Susan M., Duricki, Denise A., Reilly, Joanne M., Lax, Alistair J., Robbins, Jon

“…Pasteurella multocida toxin (PMT) activates the G-proteins Gαi(1-3), Gαq, Gα11, Gα12 and Gα13 by deamidation of specific glutamine residues. A number of these…”
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Adenosine induces a cholinergic tracheal reflex contraction in guinea pigs in vivo via an adenosine A1 receptor-dependent mechanism by Reynolds, Sandra M, Docherty, Reginald, Robbins, Jon, Spina, Domenico, Page, Clive P

“…1 Pharmaceutical Science Research Division, The Sackler Institute of Pulmonary Pharmacology, School of Biomedical and Health Science, King's College London,…”
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Nanostructured electrodes for biocompatible CMOS integrated circuits by Graham, Anthony H.D., Bowen, Chris R., Robbins, Jon, Lalev, Georgi, Marken, Frank, Taylor, John

“…This paper reports on the adaptation of standard complementary metal oxide semiconductor (CMOS) integrated circuit (IC) technology for biocompatibility,…”
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New prototype assembly methods for biosensor integrated circuits by Graham, Anthony H.D, Bowen, Chris R, Surguy, Susan M, Robbins, Jon, Taylor, John

“…Abstract Two new prototype assembly methods have been evaluated for biosensors that combine an integrated circuit (IC) sensor with a culture chamber. The first…”
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Neuronal cell biocompatibility and adhesion to modified CMOS electrodes by Graham, Anthony H. D, Bowen, Chris R, Taylor, John, Robbins, Jon

“…The use of CMOS (Complementary Metal Oxide Semiconductor) integrated circuits to create electrodes for biosensors, implants and drug-discovery has several…”
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