Search Results - "Robb, Frank T."
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genomic basis of trophic strategy in marine bacteria
Published in Proceedings of the National Academy of Sciences - PNAS (15-09-2009)“…Many marine bacteria have evolved to grow optimally at either high (copiotrophic) or low (oligotrophic) nutrient concentrations, enabling different species to…”
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Identification and characterization of a multidomain hyperthermophilic cellulase from an archaeal enrichment
Published in Nature communications (05-07-2011)“…Despite extensive studies on microbial and enzymatic lignocellulose degradation, relatively few Archaea are known to deconstruct crystalline cellulose. Here we…”
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Life on the fringe: microbial adaptation to growth on carbon monoxide [version 1; peer review: 3 approved]
Published in F1000 research (2018)“…Microbial adaptation to extreme conditions takes many forms, including specialized metabolism which may be crucial to survival in adverse conditions. Here, we…”
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Aspartic acid racemization constrains long-term viability and longevity of endospores
Published in FEMS microbiology ecology (01-10-2019)“…ABSTRACT Certain microorganisms survive long periods of time as endospores to cope with adverse conditions. Since endospores are metabolically inactive, the…”
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Evidence for horizontal gene transfer of anaerobic carbon monoxide dehydrogenases
Published in Frontiers in microbiology (01-01-2012)“…Carbon monoxide (CO) is commonly known as a toxic gas, yet both cultivation studies and emerging genome sequences of bacteria and archaea establish that CO is…”
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Novel Extracellular Electron Transfer Channels in a Gram-Positive Thermophilic Bacterium
Published in Frontiers in microbiology (11-01-2021)“…Biogenic transformation of Fe minerals, associated with extracellular electron transfer (EET), allows microorganisms to exploit high-potential refractory…”
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Structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium
Published in Nature communications (10-10-2017)“…The chaperonins (CPNs) are megadalton sized hollow complexes with two cavities that open and close to encapsulate non-native proteins. CPNs are assigned to two…”
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Detection of circular polarization in light scattered from photosynthetic microbes
Published in Proceedings of the National Academy of Sciences - PNAS (12-05-2009)“…The identification of a universal biosignature that could be sensed remotely is critical to the prospects for success in the search for life elsewhere in the…”
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The Complete Genome Sequence of Hyperthermophile Dictyoglomus turgidum DSM 6724™ Reveals a Specialized Carbohydrate Fermentor
Published in Frontiers in microbiology (20-12-2016)“…Here we report the complete genome sequence of the chemoorganotrophic, extremely thermophilic bacterium, , which is a Gram negative, strictly anaerobic…”
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A modulator domain controlling thermal stability in the Group II chaperonins of Archaea
Published in Archives of biochemistry and biophysics (01-08-2011)“…► Hyperthermophilic chaperonins (Cpn) are highly stable yet conserved with other archaeal HSP60s. ► The C-termini contain highly charged sections, divergent…”
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A human CCT5 gene mutation causing distal neuropathy impairs hexadecamer assembly in an archaeal model
Published in Scientific reports (27-10-2014)“…Chaperonins mediate protein folding in a cavity formed by multisubunit rings. The human CCT has eight non-identical subunits and the His147Arg mutation in one…”
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Archaeal-like chaperonins in bacteria
Published in Proceedings of the National Academy of Sciences - PNAS (23-11-2010)“…Chaperonins (CPN) are ubiquitous oligomeric protein machines that mediate the ATP-dependent folding of polypeptide chains. These chaperones have not only been…”
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Life in hot carbon monoxide: the complete genome sequence of Carboxydothermus hydrogenoformans Z-2901
Published in PLoS genetics (01-11-2005)“…We report here the sequencing and analysis of the genome of the thermophilic bacterium Carboxydothermus hydrogenoformans Z-2901. This species is a model for…”
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Corrigendum: Regulation of multiple carbon monoxide consumption pathways in anaerobic bacteria
Published in Frontiers in microbiology (05-07-2018)“…[This corrects the article on p. 147 in vol. 2, PMID: 21808633.]…”
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Pawnobiome: manipulation of the hologenome within one host generation and beyond
Published in Frontiers in microbiology (2015)Get full text
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Oligomerization of an archaeal group II chaperonin is mediated by N-terminal salt bridges
Published in Biochemical and biophysical research communications (23-09-2011)“…Group II chaperonins (Cpns) consist of two back-to-back octameric rings. The structural basis for progressive assembly of the hexadecamer remains unclear. To…”
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Purification, crystallization, and preliminary X-ray crystallographic analysis of the Group III chaperonin from Carboxydothermus hydrogenoformans
Published in The journal of microbiology (01-06-2016)“…Chaperonins (CPNs) are megadalton sized ATP-dependent nanomachines that facilitate protein folding through complex cycles of complex allosteric articulation…”
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Bridging human chaperonopathies and microbial chaperonins
Published in Communications biology (15-03-2019)“…Chaperonins are molecular chaperones that play critical physiological roles, but they can be pathogenic. Malfunctional chaperonins cause chaperonopathies of…”
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Prokaryotic Chaperonins as Experimental Models for Elucidating Structure-Function Abnormalities of Human Pathogenic Mutant Counterparts
Published in Frontiers in molecular biosciences (09-01-2017)“…All archaea have a chaperonin of Group II (thermosome) in their cytoplasm and some have also a chaperonin of Group I (GroEL; Cpn60; Hsp60). Conversely, all…”
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An exceptionally stable Group II chaperonin from the hyperthermophile Pyrococcus furiosus
Published in Archives of biochemistry and biophysics (01-06-2009)“…The hyperthermophilic archaeon Pyrococcus furiosus (Pf) grows optimally at 100 °C and encodes single genes for the Group II chaperonin (Cpn), Pf Cpn and…”
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