Search Results - "Robaire, Sandra A."

Design of an in vitro biocatalytic cascade for the manufacture of islatravir by Huffman, Mark A, Fryszkowska, Anna, Alvizo, Oscar, Borra-Garske, Margie, Campos, Kevin R, Canada, Keith A, Devine, Paul N, Duan, Da, Forstater, Jacob H, Grosser, Shane T, Halsey, Holst M, Hughes, Gregory J, Jo, Junyong, Joyce, Leo A, Kolev, Joshua N, Liang, Jack, Maloney, Kevin M, Mann, Benjamin F, Marshall, Nicholas M, McLaughlin, Mark, Moore, Jeffrey C, Murphy, Grant S, Nawrat, Christopher C, Nazor, Jovana, Novick, Scott, Patel, Niki R, Rodriguez-Granillo, Agustina, Robaire, Sandra A, Sherer, Edward C, Truppo, Matthew D, Whittaker, Aaron M, Verma, Deeptak, Xiao, Li, Xu, Yingju, Yang, Hao

“…Enzyme-catalyzed reactions have begun to transform pharmaceutical manufacturing, offering levels of selectivity and tunability that can dramatically improve…”
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Green and sustainable metrics: Charting the course for green-by-design small molecule API synthesis by Rose, Harrison B., Kosjek, Birgit, Armstrong, Brittany M., Robaire, Sandra A.

“…Sustainable small molecule Active Pharmaceutical Ingredient (API) manufacturing starts at the onset of route development by employing a Green-by-Design…”
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Driving Aspirational Process Mass Intensity Using Simple Structure-Based Prediction by Sherer, Edward C., Bagchi, Ansuman, Kosjek, Birgit, Maloney, Kevin M., Peng, Zhengwei, Robaire, Sandra A., Sheridan, Robert P., Metwally, Essam, Campeau, Louis-Charles

“…An important metric for gauging the impact that a synthetic route has on chemical resources, cost, and sustainability is process mass intensity (PMI)…”
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Development of a Biocatalytic Aerobic Oxidation for the Manufacturing Route to Islatravir by Shaw, Megan H., Fryszkowska, Anna, Alvizo, Oscar, Attadgie, Ilana, Borra-Garske, Margie, Devine, Paul N., Duan, Da, Grosser, Shane T., Forstater, Jacob H., Hughes, Gregory J., Maloney, Kevin M., Margelefsky, Eric L., Mattern, Keith A., Miller, Margaret T., Nawrat, Christopher C., Nazor, Jovana, Orth, Peter, Ouimet, Claire M., Robaire, Sandra A., Ruccolo, Serge, Schwalm, Erica L., Verma, Deeptak, Xiao, Li, Zhang, Victoria

“…Biocatalytic oxidations have the potential to address many synthetic challenges, enabling the selective synthesis of chiral intermediates, such as carbonyl…”
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