Search Results - "Roark, Kasie"
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1
Aryl Hydrocarbon Receptor Regulates Muc2 Production Independently of IL-22 during Colitis
Published in International journal of molecular sciences (01-02-2024)“…We previously reported that an aryl hydrocarbon receptor (AhR) ligand, indole-3-carbinol (I3C), was effective at reducing colitis severity through immune…”
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Journal Article -
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Regulation of Bacteroides acidifaciens by the aryl hydrocarbon receptor in IL-22-producing immune cells has sex-dependent consequential impact on colitis
Published in Frontiers in immunology (20-08-2024)“…Colitis is an inflammatory bowel disease (IBD) characterized by immune cell dysregulation and alterations in the gut microbiome. In our previous report, we…”
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Journal Article -
3
Aryl hydrocarbon receptor ligand supplementation impacts colitis-associated depressive-like behavior
Published in The Journal of immunology (1950) (01-05-2024)“…Abstract Colitis is an inflammatory bowel disease (IBD) with increased incidences of depression in patients. The mechanisms that define this comorbidity remain…”
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Journal Article -
4
Depressive-like behavior associated with colitis is altered after treatment with aryl hydrocarbon receptor ligand
Published in The Journal of immunology (1950) (01-05-2023)“…Abstract Colitis is a chronic inflammatory disease with no cure and an overall reduction in patient quality of life. Due to decreased mucous production and…”
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Journal Article -
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ARYL HYDROCARBON RECEPTOR REGULATES GENES IN COLONIC EPITHELIAL CELLS TO MITIGATE COLITIS SEVERITY IN THE DSS-INDUCED MURINE MODEL
Published in The Journal of immunology (1950) (01-05-2023)“…Abstract Current treatment of ulcerative colitis (UC) leaves a clear unmet need to target the colonic epithelial cells (CECs). In our previous study we found…”
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Journal Article -
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Investigation of the aryl hydrocarbon receptor’s role in colitis as it relates to observed disease-specific sex differences
Published in The Journal of immunology (1950) (01-05-2023)“…Abstract Colitis is an inflammatory bowel disease (IBD) characterized by chronic inflammation in the colon. Studies suggest that there are differences between…”
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Journal Article -
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Exploration Into the Relationship Between Colitis and Depression: A Potential Role for the Aryl Hydrocarbon Receptor
Published 01-01-2023“…Inflammatory Bowel Disease (IBD) is a group of chronic gastrointestinal disorders with unclear etiology comprised of two defined disorders – Crohn’s Disease…”
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Dissertation