Search Results - "Rizzolo, Kamran"

The PDGF signaling pathway controls multiple steroid-producing lineages by Schmahl, Jennifer, Rizzolo, Kamran, Soriano, Philippe

“…The platelet-derived growth factor (PDGF) signaling pathway regulates numerous lineages of mesenchymal cell origin during development and in the adult. The…”
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Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex by Rizzolo, Kamran, Yu, Angela Yeou Hsiung, Ologbenla, Adedeji, Kim, Sa Rang, Zhu, Haojie, Ishimori, Koichiro, Thibault, Guillaume, Leung, Elisa, Zhang, Yi Wen, Teng, Mona, Haniszewski, Marta, Miah, Noha, Phanse, Sadhna, Minic, Zoran, Lee, Sukyeong, Caballero, Julio Diaz, Babu, Mohan, Tsai, Francis T. F., Saio, Tomohide, Houry, Walid A.

“…A functional association is uncovered between the ribosome-associated trigger factor (TF) chaperone and the ClpXP degradation complex. Bioinformatic analyses…”
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Reversible inhibition of the ClpP protease via an N-terminal conformational switch by Vahidi, Siavash, Ripstein, Zev A., Bonomi, Massimiliano, Yuwen, Tairan, Mabanglo, Mark F., Juravsky, Jordan B., Rizzolo, Kamran, Velyvis, Algirdas, Houry, Walid A., Vendruscolo, Michele, Rubinstein, John L., Kay, Lewis E.

“…Protein homeostasis is critically important for cell viability. Key to this process is the refolding of misfolded or aggregated proteins by molecular…”
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Author Correction: Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex by Rizzolo, Kamran, Yu, Angela Yeou Hsiung, Ologbenla, Adedeji, Kim, Sa Rang, Zhu, Haojie, Ishimori, Koichiro, Thibault, Guillaume, Leung, Elisa, Zhang, Yi Wen, Teng, Mona, Haniszewski, Marta, Miah, Noha, Phanse, Sadhna, Minic, Zoran, Lee, Sukyeong, Caballero, Julio Diaz, Babu, Mohan, Tsai, Francis T. F., Saio, Tomohide, Houry, Walid A.

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Features of the Chaperone Cellular Network Revealed through Systematic Interaction Mapping by Rizzolo, Kamran, Huen, Jennifer, Kumar, Ashwani, Phanse, Sadhna, Vlasblom, James, Kakihara, Yoshito, Zeineddine, Hussein A., Minic, Zoran, Snider, Jamie, Wang, Wen, Pons, Carles, Seraphim, Thiago V., Boczek, Edgar Erik, Alberti, Simon, Costanzo, Michael, Myers, Chad L., Stagljar, Igor, Boone, Charles, Babu, Mohan, Houry, Walid A.

“…A comprehensive view of molecular chaperone function in the cell was obtained through a systematic global integrative network approach based on physical…”
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ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores by Mabanglo, Mark F., Leung, Elisa, Vahidi, Siavash, Seraphim, Thiago V., Eger, Bryan T., Bryson, Steve, Bhandari, Vaibhav, Zhou, Jin Lin, Mao, Yu-Qian, Rizzolo, Kamran, Barghash, Marim M., Goodreid, Jordan D., Phanse, Sadhna, Babu, Mohan, Barbosa, Leandro R. S., Ramos, Carlos H. I., Batey, Robert A., Kay, Lewis E., Pai, Emil F., Houry, Walid A.

“…Bacterial ClpP is a highly conserved, cylindrical, self-compartmentalizing serine protease required for maintaining cellular proteostasis. Small molecule…”
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Functional Cooperativity between the Trigger Factor Chaperone and the ClpXP Proteolytic Complex by Houry, Walid, Rizzolo, Kamran

“…A functional association is uncovered between the ribosome‐associated trigger factor (TF) chaperone and the ClpXP degradation complex. Bioinformatic analyses…”
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Flipping the switch by Rizzolo, Kamran, Mitrea, Diana M.

“…Biomolecular condensates form and dissolve in response to a wide range of signals. A new study reports a solubility-based phosphoproteome-profiling approach,…”
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Multiple functionalities of molecular chaperones revealed through systematic mapping of their interaction networks by Rizzolo, Kamran, Houry, Walid A.

“…Chaperones are a highly interactive group of proteins that function globally in many cellular processes involved in maintaining protein homeostasis…”
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Acyldepsipeptide Analogs Dysregulate Human Mitochondrial ClpP Protease Activity and Cause Apoptotic Cell Death by Wong, Keith S, Mabanglo, Mark F, Seraphim, Thiago V, Mollica, Antonio, Mao, Yu-Qian, Rizzolo, Kamran, Leung, Elisa, Moutaoufik, Mohamed T, Hoell, Larissa, Phanse, Sadhna, Goodreid, Jordan, Barbosa, Leandro R S, Ramos, Carlos H I, Babu, Mohan, Mennella, Vito, Batey, Robert A, Schimmer, Aaron D, Houry, Walid A

“…Acyldepsipeptides (ADEPs) are potential antibiotics that dysregulate the activity of the highly conserved tetradecameric bacterial ClpP protease, leading to…”
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Computational Analysis of the Chaperone Interaction Networks by Kumar, Ashwani, Rizzolo, Kamran, Zilles, Sandra, Babu, Mohan, Houry, Walid A

“…We provide computational protocols to identify chaperone interacting proteins using a combination of both physical (protein-protein) and genetic (gene-gene or…”
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Novel function discovery with GeneMANIA: a new integrated resource for gene function prediction in Escherichia coli by Vlasblom, James, Zuberi, Khalid, Rodriguez, Harold, Arnold, Roland, Gagarinova, Alla, Deineko, Viktor, Kumar, Ashwani, Leung, Elisa, Rizzolo, Kamran, Samanfar, Bahram, Chang, Luke, Phanse, Sadhna, Golshani, Ashkan, Greenblatt, Jack F, Houry, Walid A, Emili, Andrew, Morris, Quaid, Bader, Gary, Babu, Mohan

“…The model bacterium Escherichia coli is among the best studied prokaryotes, yet nearly half of its proteins are still of unknown biological function. This is…”
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A scalable, fully automated process for construction of sequence-ready barcoded libraries for 454 by Lennon, Niall J, Lintner, Robert E, Anderson, Scott, Alvarez, Pablo, Barry, Andrew, Brockman, William, Daza, Riza, Erlich, Rachel L, Giannoukos, Georgia, Green, Lisa, Hollinger, Andrew, Hoover, Cindi A, Jaffe, David B, Juhn, Frank, McCarthy, Danielle, Perrin, Danielle, Ponchner, Karen, Powers, Taryn L, Rizzolo, Kamran, Robbins, Dana, Ryan, Elizabeth, Russ, Carsten, Sparrow, Todd, Stalker, John, Steelman, Scott, Weiand, Michael, Zimmer, Andrew, Henn, Matthew R, Nusbaum, Chad, Nicol, Robert

“…We present an automated, high throughput library construction process for 454 technology. Sample handling errors and cross-contamination are minimized via…”
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ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores by Mabanglo, Mark F, Leung, Elisa, Vahidi, Siavash, Seraphim, Thiago V, Eger, Bryan T, Bryson, Steve, Bhandari, Vaibhav, Zhou, Jin Lin, Mao, Yu-Qian, Rizzolo, Kamran, Barghash, Marim M, Goodreid, Jordan D, Phanse, Sadhna, Babu, Mohan, Barbosa, Leandro R S, Ramos, Carlos H I, Batey, Robert A, Kay, Lewis E, Pai, Emil F, Houry, Walid A

“…Bacterial ClpP is a highly conserved, cylindrical, self-compartmentalizing serine protease required for maintaining cellular proteostasis. Small molecule…”
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Chaperone Systems in Model Organisms by Rizzolo Roustayan, Kamran Daniel

“…Molecular chaperones are typically promiscuous interacting proteins that function globally in the cell for quality control and maintenance of protein…”
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Genetic dissection of virulence and immune-eliciting functions and characterization of the immune response of the Pseudomonas syringae HopZ1 Type III effector family by Rizzolo Roustayan, Kamran Daniel

“…Successful pathogens like Pseudomonas syringae translocate type III effector proteins (T3SE) into host cells. Plant hosts react by specifically recognizing…”
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