Search Results - "Rizzo, Gabrielle"

A novel approach to interrogating the effects of chemical warfare agent exposure using organ-on-a-chip technology and multiomic analysis by Goralski, Tyler D P, Jenkins, Conor C, Angelini, Daniel J, Horsmon, Jennifer R, Dhummakupt, Elizabeth S, Rizzo, Gabrielle M, Simmons, Brooke L, Liem, Alvin T, Roth, Pierce A, Karavis, Mark A, Hill, Jessica M, Sekowski, Jennifer W, Glover, Kyle P

“…Organ-on-a-chip platforms are utilized in global bioanalytical and toxicological studies as a way to reduce materials and increase throughput as compared to in…”
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Proteomic Characterization of Immunoglobulin Content in Dermal Interstitial Fluid by Arévalo, Maria T, Rizzo, Gabrielle M, Polsky, Ronen, Glaros, Trevor, Mach, Phillip M

“…Microneedles have been demonstrated to be a minimally invasive technique for sampling dermal interstitial fluid (ISF). Shotgun quantitative proteomics has…”
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Multiomic analysis of Lewisite exposed human dermal equivalent tissues by Dhummakupt, Elizabeth S., Jenkins, Conor C., Rizzo, Gabrielle M., Clay, Allison E., Horsmon, Jennifer R., Goralski, Tyler D.P., Renner, Julie A., Angelini, Daniel J.

“…Lewisite (Military Code: L) is an arsenical vesicant chemical warfare agent (CWA) that was developed in the United States during World War I. Even though its…”
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Normalization of organ-on-a-Chip samples for mass spectrometry based proteomics and metabolomics via Dansylation-based assay by Gallagher, Erin M., Rizzo, Gabrielle M., Dorsey, Russell, Dhummakupt, Elizabeth S., Moran, Theodore S., Mach, Phillip M., Jenkins, Conor C.

“…Mass spectrometry based ‘omics pairs well with organ-on-a-chip-based investigations, which often have limited cellular material for sampling. However, a common…”
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On‐substrate derivatization for detection of highly volatile G‐series chemical warfare agents via paper spray mass spectrometry by Mach, Phillip M., Dhummakupt, Elizabeth S., Carmany, Daniel O., McBride, Ethan M., Busch, Michael W., Demond, Paul S., Rizzo, Gabrielle M., Hollinshead, Donna E., Glaros, Trevor

“…Rationale The analysis of chemical warfare agents (CWAs) from ambient atmosphere presents an analytical challenge due to their ease of degradation and…”
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Discovery of treatment for nerve agents targeting a new metabolic pathway by Glaros, Trevor, Dhummakupt, Elizabeth S., Rizzo, Gabrielle M., McBride, Ethan, Carmany, Daniel O., Wright, Linnzi K. M., Forster, Jeffry S., Renner, Julie A., Moretz, Ruth W., Dorsey, Russell, Marten, Mark R., Huso, Walker, Doan, Alexander, Dorsey, Carrie D., Phillips, Christopher, Benton, Bernard, Mach, Phillip M.

“…The inhibition of acetylcholinesterase is regarded as the primary toxic mechanism of action for chemical warfare agents. Recently, there have been numerous…”
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On-substrate Enzymatic Reaction to Determine Acetylcholinesterase Activity in Whole Blood by Paper Spray Mass Spectrometry by Carmany, Daniel O., Mach, Phillip M., Rizzo, Gabrielle M., Dhummakupt, Elizabeth S., McBride, Ethan M., Sekowski, Jennifer W., Benton, Bernard, Demond, Paul S., Busch, Michael W., Glaros, Trevor

“…Currently, all assays measuring acetylcholinesterase (AChE) activity following a suspected nerve agent exposure leverage methodologies that fail to identify…”
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Proteomic, Metabolomic, and Lipidomic Analyses of Lung Tissue Exposed to Mustard Gas by Dhummakupt, Elizabeth, Jenkins, Conor, Rizzo, Gabrielle, Melka, Allison, Carmany, Daniel, Prugh, Amber, Horsmon, Jennifer, Renner, Julie, Angelini, Daniel

“…Sulfur mustard (HD) poses a serious threat due to its relatively simple production process. Exposure to HD in the short-term causes an inflammatory response,…”
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Proteomic and Metabolomic Profiling Identify Plasma Biomarkers for Exposure to Ultra-low Levels of Carfentanil by Dhummakupt, Elizabeth S, Rizzo, Gabrielle M, Feasel, Michael, Mach, Phillip M, Tran, Bao Q, Carmany, Daniel O, Demond, Paul S, McBride, Ethan M, Maughan, Michele, Sekowski, Jennifer W, Glaros, Trevor

“…Abstract Despite the recent epidemic of fentanyl abuse, there are few validated assays capable of rapidly detecting these compounds. In order to improve the…”
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Supplemental Ascorbate Diminishes DNA Damage Yet Depletes Glutathione and Increases Acute Liver Failure in a Mouse Model of Hepatic Antioxidant System Disruption by Miller, Colin G, Kundert, Jean A, Prigge, Justin R, Amato, Julie A, Perez, Allison E, Coppo, Lucia, Rizzo, Gabrielle N, Kavanaugh, Michael P, Orlicky, David J, Shearn, Colin T, Schmidt, Edward E

“…Cellular oxidants are primarily managed by the thioredoxin reductase-1 (TrxR1)- and glutathione reductase (Gsr)-driven antioxidant systems. In mice having…”
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Purification and Proteomic Analysis of Alphavirus Particles from Sindbis Virus Grown in Mammalian and Insect Cells by Hernandez, Raquel, Glaros, Trevor, Rizzo, Gabrielle, Ferreira, Davis F

“…Current mass spectrometry (MS) methods and new instrumentation now allow for more accurate identification of proteins in low abundance than previous protein…”
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Paper spray ionization: Applications and perspectives by McBride, Ethan M., Mach, Phillip M., Dhummakupt, Elizabeth S., Dowling, Sarah, Carmany, Daniel O., Demond, Paul S., Rizzo, Gabrielle, Manicke, Nicholas E., Glaros, Trevor

“…Paper spray ionization has grown to become one of the most successful ambient ionization methods within the past decade. Requiring little to no sample…”
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Cover Image by Mach, Phillip M., Dhummakupt, Elizabeth S., Carmany, Daniel O., McBride, Ethan M., Busch, Michael W., Demond, Paul S., Rizzo, Gabrielle M., Hollinshead, Donna E., Glaros, Trevor

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A novel approach to interrogating the effects of chemical warfare agent exposure using organ-on-a-chip technology and multiomic analysis by Tyler D P Goralski, Conor C Jenkins, Daniel J Angelini, Jennifer R Horsmon, Elizabeth S Dhummakupt, Gabrielle M Rizzo, Brooke L Simmons, Alvin T Liem, Pierce A Roth, Mark A Karavis, Jessica M Hill, Jennifer W Sekowski, Kyle P Glover

“…Organ-on-a-chip platforms are utilized in global bioanalytical and toxicological studies as a way to reduce materials and increase throughput as compared to in…”
Get full text