Search Results - "Rizwan, Mohammed Z."
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Hyperleptinemia as a contributing factor for the impairment of glucose intolerance in obesity
Published in The FASEB journal (01-02-2021)“…Obesity has emerged as a major risk factor for insulin resistance leading to the development of type 2 diabetes (T2D). The condition is characterized by high…”
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2
RFamide-Related Peptide Neurons Modulate Reproductive Function and Stress Responses
Published in The Journal of neuroscience (20-01-2021)“…RF-amide related peptide 3 (RFRP-3) is a neuropeptide thought to inhibit central regulation of fertility. We investigated whether alterations in RFRP neuronal…”
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RFamide-Related Peptide-3 Receptor Gene Expression in GnRH and Kisspeptin Neurons and GnRH-Dependent Mechanism of Action
Published in Endocrinology (Philadelphia) (01-08-2012)“…RFamide-related peptide-3 (RFRP-3) is known to inhibit the activity of GnRH neurons. It is not yet clear whether its G protein-coupled receptors, GPR147 and…”
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4
Central and Peripheral Effects of RFamide-Related Peptide-3 on Luteinizing Hormone and Prolactin Secretion in Rats
Published in Endocrinology (Philadelphia) (01-04-2009)“…Hypothalamic RFamide-related peptide-3 (RFRP-3) neurons inhibit LH secretion via a central action. A direct hypophysiotropic action on the gonadotropes has…”
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5
Hypothalamic leptin sensitivity and health benefits of time‐restricted feeding are dependent on the time of day in male mice
Published in The FASEB journal (01-11-2019)“…Synchronization between biologic clocks and metabolism is crucial for most species. Here, we examined the ability of leptin, important in the control of energy…”
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A New Zealand green-lipped mussel oil-enriched high-fat diet exhibits beneficial effects on body weight and metabolism in mice
Published in British journal of nutrition (14-05-2021)“…To induce diet-induced obesity (DIO) in rodents, diets high in saturated fat and/or carbohydrates are commonly used. In the laboratory, standardised diets…”
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Dietary wheat gluten induces astro‐ and microgliosis in the hypothalamus of male mice
Published in Journal of neuroendocrinology (01-08-2023)“…Gluten, which is found in cereals such as wheat, rye and barley, makes up a major dietary component in most western nations, and has been shown to promote body…”
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8
Conditional Deletion of β-Catenin in the Mediobasal Hypothalamus Impairs Adaptive Energy Expenditure in Response to High-Fat Diet and Exacerbates Diet-Induced Obesity
Published in The Journal of neuroscience (03-04-2024)“…β-Catenin is a bifunctional molecule that is an effector of the wingless-related integration site (Wnt) signaling to control gene expression and contributes to…”
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9
Chronic Light Cycle Disruption Alters Central Insulin and Leptin Signaling as well as Metabolic Markers in Male Mice
Published in Endocrinology (Philadelphia) (01-10-2019)“…Abstract Recent evidence suggests that the circadian timing system plays a role in energy and glucose homeostasis, and disruptions to this system are a risk…”
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10
Leptin regulates glucose homeostasis via the canonical Wnt pathway in the zebrafish
Published in The FASEB journal (01-03-2022)“…Leptin is best known for its role in adipostasis, but it also regulates blood glucose levels. The molecular mechanism by which leptin controls glucose…”
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Cells Expressing RFamide-Related Peptide-1/3, the Mammalian Gonadotropin-Inhibitory Hormone Orthologs, Are Not Hypophysiotropic Neuroendocrine Neurons in the Rat
Published in Endocrinology (Philadelphia) (01-03-2009)“…An RFamide peptide named gonadotropin-inhibitory hormone, which directly inhibits gonadotropin synthesis and secretion from the anterior pituitary gland, has…”
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12
Insulin Action on GABA Neurons Is a Critical Regulator of Energy Balance But Not Fertility in Mice
Published in Endocrinology (Philadelphia) (01-11-2014)“…Insulin signaling in the brain plays an important role in the central regulation of energy homeostasis and fertility, such that mice exhibiting brain-specific…”
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“Insulin-like” effects of palmitate compromise insulin signalling in hypothalamic neurons
Published in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology (01-08-2019)“…Saturated fatty acids are implicated in the development of metabolic diseases, including obesity and type 2 diabetes. There is evidence, however, that…”
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Leptin Signaling Is Not Required for Anorexigenic Estradiol Effects in Female Mice
Published in Endocrinology (Philadelphia) (01-05-2016)“…Estradiol and leptin are critical hormones in the regulation of body weight. The aim of this study was to determine whether this cross talk between leptin…”
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15
Stabilization of beta catenin in hypothalamic cell lines
Published in Obesity research & clinical practice (01-05-2019)Get full text
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