Search Results - "Rizvi, Yasmeen"
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The simultaneous effect of green ability-motivation-opportunity and transformational leadership in environment management: the mediating role of green culture
Published in Benchmarking : an international journal (29-03-2021)“…PurposeManagers and management studies have for long assumed the separation of humans and nature that led to criticisms due to overexploitation of resources…”
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Adavosertib Enhances Antitumor Activity of Trastuzumab Deruxtecan in HER2-Expressing Cancers
Published in Clinical cancer research (01-11-2023)“…Cyclin E (CCNE1) has been proposed as a biomarker of sensitivity to adavosertib, a Wee1 kinase inhibitor, and a mechanism of resistance to HER2-targeted…”
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Serum Glucocorticoid-Regulated Kinase 1 Blocks CKD-Induced Muscle Wasting Via Inactivation of FoxO3a and Smad2/3
Published in Journal of the American Society of Nephrology (01-09-2016)“…Muscle proteolysis in CKD is stimulated when the ubiquitin-proteasome system is activated. Serum glucocorticoid-regulated kinase 1 (SGK-1) is involved in…”
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Combined MEK/MDM2 inhibition demonstrates antitumor efficacy in TP53 wild-type thyroid and colorectal cancers with MAPK alterations
Published in Scientific reports (24-01-2022)“…Most tumors with activating MAPK (mitogen-activated protein kinase) pathway alterations respond poorly to MEK inhibitors alone. Here, we evaluated combination…”
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Human Capital Development Role of HR during Mergers and Acqusitions
Published in The South East Asian journal of management (08-04-2016)Get full text
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Combined inhibition of DDR1 and CDK4/6 induces synergistic effects in ER-positive, HER2-negative breast cancer with PIK3CA/AKT1 mutations
Published in Oncogene (01-07-2021)“…Molecular alterations in the PI3K/AKT pathway occur frequently in hormone receptor-positive breast tumors. Patients with ER-positive, HER2-negative metastatic…”
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From anthropocentrism to sustaincentrism: case study on beverage companies in India
Published in Holistic approach to environment (17-06-2021)“…Business organizations have been facing an unprecedented level of criticisms for being one of the prime contributors to the deterioration of environmental…”
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A Novel Dual Kinase Function of the RET Proto-oncogene Negatively Regulates Activating Transcription Factor 4-mediated Apoptosis
Published in The Journal of biological chemistry (01-05-2015)“…The RET proto-oncogene, a tyrosine kinase receptor, is widely known for its essential role in cell survival. Germ line missense mutations, which give rise to…”
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Oncogenic and osteolytic functions of histone demethylase NO66 in castration-resistant prostate cancer
Published in Oncogene (01-06-2019)“…Epigenetic changes that cause dysregulated gene expression during progression of androgen-independent prostate cancer (PCa) and metastatic skeletal lesions…”
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Co-clinical Trial of Novel Bispecific Anti-HER2 Antibody Zanidatamab in Patient-Derived Xenografts
Published in Cancer discovery (01-05-2024)“…Zanidatamab is a bispecific human epidermal growth factor receptor 2 (HER2)-targeted antibody that has demonstrated antitumor activity in a broad range of…”
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Interactions of PPAR-alpha and adenosine receptors in hypoxia-induced angiogenesis
Published in Vascular pharmacology (01-11-2013)“…Abstract Hypoxia and adenosine are known to upregulate angiogenesis; however, the role of peroxisome proliferator-activated receptor alpha (PPARα) in…”
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Corporate social responsibility and psychological capital during the COVID-19 pandemic: perspectives from India
Published in Social responsibility journal (18-10-2023)“…Purpose This paper aims to examine the relationship between employees’ perception of corporate social responsibility (CSR) practices in Indian business…”
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Transformation of Learning from Real to Virtual: An Exploratory-Descriptive Analysis of Issues and Challenges
Published in Journal of research in innovative teaching (01-01-2021)“…Purpose: As online teaching/learning is a new phenomenon with reference to regular degree programs in institutions of higher education in India (the situation…”
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Epigenetically upregulating TROP2 and SLFN11 enhances therapeutic efficacy of TROP2 antibody drug conjugate sacitizumab govitecan
Published in NPJ breast cancer (11-08-2023)“…TROP2 antibody drug conjugates (ADCs) are under active development. We seek to determine whether we can enhance activity of TROP2 ADCs by increasing TROP2…”
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Learned Helplessness at the Workplace and Its Impact on Work Involvement: An Empirical Analysis
Published in Global business review (18-12-2020)“…In today’s work environment that is characterized by rapid advancements in technology, globalization, liberalization, workforce diversity and increasing…”
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Abstract PS18-37: Loss of Trop2 protein in metaplastic carcinoma of breast by IHC
Published in Cancer research (Chicago, Ill.) (15-02-2021)“…Abstract Background: Trop2 (trophoblast cell surface antigen) is a transmembrane calcium transducer which has been associated with tumor growth, aggressiveness…”
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Utilizing Patient-derived Xenografts to Model Precision Oncology for Biliary Tract Cancer
Published in Clinical cancer research (08-11-2024)“…Abstract Purpose: Biliary tract cancers (BTCs), which are rare and aggressive malignancies, are rich in clinically actionable molecular alterations. A major…”
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Heterogeneous Profile of ROR1 Protein Expression across Tumor Types
Published in Cancers (15-05-2024)“…The Wnt receptor ROR1 has generated increased interest as a cancer therapeutic target. Research on several therapeutic approaches involving this receptor is…”
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Interactions of peroxisome proliferator‐activated receptor alpha (PPARá) and adenosine receptors (AR) in angiogenesis
Published in The FASEB journal (01-04-2011)“…Hypoxia (HYP) stimulates angiogenesis (ANG) by promoting expression of many pro‐angiogenic genes, including AR. The role of PPARα in ANG is controversial…”
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Abstract P058: Anti-tumor activity of ATR inhibitor BAY 1895344 in patient-derived xenograft (PDX) models with DNA damage response (DDR) pathway alterations
Published in Molecular cancer therapeutics (01-12-2021)“…Abstract Introduction: The ATR (ataxia-telangiectasia and Rad3 related protein) kinase inhibitor BAY 1895344 is currently in clinical development for the…”
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