Search Results - "Rizoli, Sandro"
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Harmful or Physiologic: Diagnosing Fibrinolysis Shutdown in a Trauma Cohort With Rotational Thromboelastometry
Published in Anesthesia and analgesia (01-10-2018)“…BACKGROUND:Despite its central role in early trauma coagulopathy, abnormal fibrinolysis continues to be poorly understood. Excessive fibrinolysis is a known…”
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Effect of thromboelastography (TEG®) and rotational thromboelastometry (ROTEM®) on diagnosis of coagulopathy, transfusion guidance and mortality in trauma: descriptive systematic review
Published in Critical care (London, England) (27-09-2014)“…The understanding of coagulopathies in trauma has increased interest in thromboelastography (TEG®) and thromboelastometry (ROTEM®), which promptly evaluate the…”
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Detailed Description of All Deaths in Both the Shock and Traumatic Brain Injury Hypertonic Saline Trials of the Resuscitation Outcomes Consortium
Published in Annals of surgery (01-03-2015)“…OBJECTIVE:To identify causes and timing of mortality in trauma patients to determine targets for future studies. BACKGROUND:In trials conducted by the…”
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Thromboelastography and rotational thromboelastometry for the surgical intensivist: A narrative review
Published in The journal of trauma and acute care surgery (01-04-2019)“…Viscoelastic tests (VETs), specifically thromboelastography (TEG) and rotational thromboelastometry (ROTEM), are gaining popularity in the management of…”
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Catecholamines as outcome markers in isolated traumatic brain injury: the COMA-TBI study
Published in Critical care (London, England) (23-02-2017)“…Elevated catecholamine levels might be associated with unfavorable outcome after traumatic brain injury (TBI). We investigated the association between…”
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A systematic review on the rotational thrombelastometry (ROTEM®) values for the diagnosis of coagulopathy, prediction and guidance of blood transfusion and prediction of mortality in trauma patients
Published in Scandinavian journal of trauma, resuscitation and emergency medicine (03-10-2016)“…Inneholder sammendrag…”
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Inflammatory cytokine and chemokine profiles are associated with patient outcome and the hyperadrenergic state following acute brain injury
Published in Journal of neuroinflammation (16-02-2016)“…Traumatic brain injury (TBI) elicits intense sympathetic nervous system (SNS) activation with profuse catecholamine secretion. The resultant hyperadrenergic…”
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Improving Temporal Trends in Survival and Neurological Outcomes After Out-of-Hospital Cardiac Arrest
Published in Circulation Cardiovascular quality and outcomes (01-01-2018)“…Considerable effort has gone into improving outcomes from out-of-hospital cardiac arrest (OHCA). Studies suggest that survival is improving; however, prior…”
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The FASILA Score: A Novel Bio-Clinical Score to Predict Massive Blood Transfusion in Patients with Abdominal Trauma
Published in World journal of surgery (01-04-2020)“…Background Early identification of patients who may need massive blood transfusion remains a major challenge in trauma care. This study proposed a novel and…”
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Maturation process and international accreditation of trauma system in a rapidly developing country
Published in PloS one (10-12-2020)“…As trauma systems mature, they are expected to improve patient care, reduce in-hospital complications and optimize outcomes. Qatar has a single trauma center,…”
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The evolving role of extracellular vesicles (exosomes) as biomarkers in traumatic brain injury: Clinical perspectives and therapeutic implications
Published in Frontiers in aging neuroscience (06-10-2022)“…Developing effective disease-modifying therapies for neurodegenerative diseases (NDs) requires reliable diagnostic, disease activity, and progression…”
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Prehospital resuscitation with hypertonic saline-dextran modulates inflammatory, coagulation and endothelial activation marker profiles in severe traumatic brain injured patients
Published in Journal of neuroinflammation (18-01-2010)“…Traumatic brain injury (TBI) initiates interrelated inflammatory and coagulation cascades characterized by wide-spread cellular activation, induction of…”
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Sympathoadrenal Activation is Associated with Acute Traumatic Coagulopathy and Endotheliopathy in Isolated Brain Injury
Published in Shock (Augusta, Ga.) (01-09-2016)“…BACKGROUND:Acute coagulopathy after traumatic brain injury (TBI) involves a complex multifactorial hemostatic response that is poorly characterized…”
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Societal Costs of Inappropriate Emergency Department Thoracotomy
Published in Journal of the American College of Surgeons (2012)“…Background Emergency department (ED) thoracotomy can be lifesaving. It can also lead to resource waste and exposure to blood-borne infections. We investigated…”
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Reducing Time-to-Treatment Decreases Mortality of Trauma Patients with Acute Subdural Hematoma
Published in Annals of surgery (01-06-2011)“…To determine if reducing prehospital time and time-to-craniotomy is associated with decreased mortality in trauma patients with acute subdural hematomas…”
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Systemic and cerebro-cardiac biomarkers following traumatic brain injury: an interim analysis of randomized controlled clinical trial of early administration of beta blockers
Published in Scientific reports (23-08-2024)“…This is an interim analysis of the Beta-blocker (Propranolol) use in traumatic brain injury (TBI) based on the high-sensitive troponin status (BBTBBT) study…”
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The impact of hypothermia on outcomes in massively transfused patients
Published in The journal of trauma and acute care surgery (01-03-2019)“…Hypothermia is associated with poor outcomes after injury. The relationship between hypothermia during contemporary large volume resuscitation and blood…”
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TEG® and ROTEM® in trauma: similar test but different results?
Published in World journal of emergency surgery (22-08-2012)“…Transfusion in trauma is often empiric or based on traditional lab tests. Viscoelastic tests such as thromboelastography (TEG®) and rotational…”
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Seizure Prophylaxis in Young Patients Following Traumatic Brain Injury
Published in Journal of emergencies, trauma and shock (01-01-2024)“…Phenytoin is one of the commonly used anti.seizure medications in nontraumatic seizures. However, its utility and safety in young patients with traumatic brain…”
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Publications and retracted articles of COVID-19 pharmacotherapy-related research: A systematic review
Published in Science Progress (01-04-2021)“…The current COVID-19 pandemic situation has stimulated an unplanned clinical research paradigm which is evident from the surge of clinical trial registrations…”
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