Search Results - "Rivlin, Noa"
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Mapping synaptic cortico‐claustral connectivity in the mouse
Published in Journal of comparative neurology (1911) (15-04-2017)“…The claustrum is an intriguing brain structure, featuring the highest connectivity per regional volume in the brain. It is a thin and elongated structure…”
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Correction to: An automated group‑housed oral fentanyl self‑administration method in mice
Published in Psychopharmacology (30-01-2024)Get full text
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p53 orchestrates between normal differentiation and cancer
Published in Seminars in cancer biology (01-06-2015)“…Abstract During recent years, it is becoming more and more evident that there is a tight connection between abnormal differentiation processes and cancer…”
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Mutant p53 facilitates somatic cell reprogramming and augments the malignant potential of reprogrammed cells
Published in The Journal of experimental medicine (27-09-2010)“…p53 deficiency enhances the efficiency of somatic cell reprogramming to a pluripotent state. As p53 is usually mutated in human tumors and many mutated forms…”
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Rescue of embryonic stem cells from cellular transformation by proteomic stabilization of mutant p53 and conversion into WT conformation
Published in Proceedings of the National Academy of Sciences - PNAS (13-05-2014)“…p53 is a well-known tumor suppressor that is mutated in over 50% of human cancers. These mutations were shown to exhibit gain of oncogenic function compared…”
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The Claustrum Supports Resilience to Distraction
Published in Current biology (10-09-2018)“…A barrage of information constantly assaults our senses, of which only a fraction is relevant at any given point in time. However, the neural circuitry…”
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Claustral Neurons Projecting to Frontal Cortex Mediate Contextual Association of Reward
Published in Current biology (21-09-2020)“…The claustrum is a small nucleus, exhibiting vast reciprocal connectivity with cortical, subcortical, and midbrain regions. Recent studies, including ours,…”
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Thymospheres Are Formed by Mesenchymal Cells with the Potential to Generate Adipocytes, but Not Epithelial Cells
Published in Cell reports (Cambridge) (24-10-2017)“…Evidence suggests that a stem-cell-driven differentiation hierarchy maintains the dynamic thymic epithelial cell (TEC) network that governs T lymphocyte…”
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Claustrum neurons projecting to the anterior cingulate restrict engagement during sleep and behavior
Published in Nature communications (26-06-2024)“…The claustrum has been linked to attention and sleep. We hypothesized that this reflects a shared function, determining responsiveness to stimuli, which spans…”
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p53 Regulates the Ras Circuit to Inhibit the Expression of a Cancer-Related Gene Signature by Various Molecular Pathways
Published in Cancer research (Chicago, Ill.) (15-03-2010)“…In this study, we focus on the analysis of a previously identified cancer-related gene signature (CGS) that underlies the cross talk between the p53 tumor…”
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COVID‐19 Breakthrough Infections in Vaccinated Patients With CLL in Israel
Published in HemaSphere (01-02-2023)Get full text
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An automated group-housed oral fentanyl self-administration method in mice
Published in Psychopharmacology (22-01-2024)“…Social factors play a critical role in human drug addiction, and humans often consume drugs together with their peers. In contrast, in traditional animal…”
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Mutations in the p53 Tumor Suppressor Gene: Important Milestones at the Various Steps of Tumorigenesis
Published in Genes & cancer (01-04-2011)“…Inactivation of the p53 tumor suppressor is a frequent event in tumorigenesis. In most cases, the p53 gene is mutated, giving rise to a stable mutant protein…”
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Claustral neurons projecting to frontal cortex restrict opioid consumption
Published in Current biology (10-07-2023)“…The synthetic opioid fentanyl is a major contributor to the current opioid addiction crisis. We report that claustral neurons projecting to the frontal cortex…”
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p53, a novel regulator of lipid metabolism pathways
Published in Journal of hepatology (01-03-2012)“…Background & Aims In this study we aimed at characterizing the regulation of hepatic metabolic pathways by the p53 transcription factor. Methods Analysis of…”
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Management and outcome of 500 multiple myeloma patients treated for first relapse outside clinical studies
Published in Annals of hematology (01-11-2023)“…Treatment options for multiple myeloma (MM) at 1st relapse are expanding. The current study compared common 2nd line regimens administered in a real-world…”
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Chemotherapeutic agents induce the expression and activity of their clearing enzyme CYP3A4 by activating p53
Published in Carcinogenesis (New York) (01-01-2013)“…Cytochrome P450 (P450) enzymes are abundantly expressed in the human liver where they hydroxylate organic substrates. In a microarray screen performed in human…”
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