Search Results - "Rivier, Catherine L."

Alcohol self-administration acutely stimulates the hypothalamic-pituitary-adrenal axis, but alcohol dependence leads to a dampened neuroendocrine state by Richardson, Heather N., Lee, Soon Y., O'Dell, Laura E., Koob, George F., Rivier, Catherine L.

“…Clinical studies link disruption of the neuroendocrine stress system with alcoholism, but remaining unknown is whether functional differences in the…”
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Corticotropin-releasing factor peptide antagonists: Design, characterization and potential clinical relevance by Rivier, Jean E, Rivier, Catherine L

“…Highlights • CRFs are mediators of gut, heart, skin, immune system and CNS homeostasis. • First antagonist α-helical CRF(9–41) is potent in the brain, less…”
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Regulation of the Hypothalamic-Pituitary-Adrenal Axis by Cytokines: Actions and Mechanisms of Action by TURNBULL, ANDREW V, RIVIER, CATHERINE L

“…ANDREW V. TURNBULL AND CATHERINE L. RIVIER The Clayton Foundation Laboratories for Peptide Biology, The Salk Institute, La Jolla, California; and North Western…”
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Urocortin 1 Inhibits Rat Leydig Cell Function by Rivier, Catherine L

“…Corticotropin-releasing factor (CRF) has previously been reported in rat testes in which it inhibits Leydig cells activity. However, recent studies in our…”
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Exposure to Repetitive Versus Varied Stress during Prenatal Development Generates Two Distinct Anxiogenic and Neuroendocrine Profiles in Adulthood by Richardson, Heather N, Zorrilla, Eric P, Mandyam, Chitra D, Rivier, Catherine L

“…Early life experiences can shape brain function and behavior in adulthood. The present study sought to elucidate the effects of repetitive, predictable vs…”
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Stress experienced in utero reduces sexual dichotomies in neurogenesis, microenvironment, and cell death in the adult rat hippocampus by Mandyam, Chitra D., Crawford, Elena F., Eisch, Amelia J., Rivier, Catherine L., Richardson, Heather N.

“…Hippocampal function and plasticity differ with gender, but the regulatory mechanisms underlying sex differences remain elusive and may be established early in…”
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Effects of naltrexone, duloxetine, and a corticotropin-releasing factor type 1 receptor antagonist on binge-like alcohol drinking in rats by Ji, Dong, Gilpin, Nicholas W, Richardson, Heather N, Rivier, Catherine L, Koob, George F

“…A ‘binge’ is defined by National Institute on Alcohol Abuse and Alcoholism as an excessive pattern of alcohol drinking that produces blood–alcohol levels…”
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Role of Corticotropin-Releasing Factor Receptors Type 1 and 2 in Modulating the Rat Adrenocorticotropin Response to Stressors by Rivier, Catherine L, Grigoriadis, Dimitri E, Rivier, Jean E

“…We investigated the contribution of corticotropin-releasing factor (CRF) receptors types 1 and 2 (CRF1 and CRF2) in mediating the ACTH response to shock,…”
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Nitric Oxide and Carbon Monoxide Have a Stimulatory Role in the Hypothalamic-Pituitary-Adrenal Response to Physico-Emotional Stressors in Rats by Kim, C. Kwon, Rivier, Catherine L.

“…Abstract We tested the hypothesis that nitric oxide and carbon monoxide, which are produced in the brain by nitric oxide synthase (NOS) and heme oxygenase…”
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A Hypothalamic-Testicular Neural Pathway Is Influenced by Brain Catecholamines, But Not Testicular Blood Flow by Selvage, Daniel J, Lee, Soon Y, Parsons, Loren H, Seo, Dong O, Rivier, Catherine L

“…We previously reported the existence of a descending multisynaptic, pituitary-independent, neural pathway between the hypothalamus and the testes in the male…”
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Comparison Between the Influence of the Systemic and Central Injection of Alcohol on Leydig Cell Activity by Selvage, Daniel J., Hales, D. Buchanan, Rivier, Catherine L.

“…: Background: Systemic alcohol exposure lowers plasma testosterone (T) levels in adult males, but the relative role of impaired luteinizing hormone…”
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Constrained Corticotropin Releasing Factor Antagonists (Astressin Analogues) with Long Duration of Action in the Rat by Rivier, Jean E, Kirby, Dean A, Lahrichi, Sabine L, Corrigan, Anne, Vale, Wylie W, Rivier, Catherine L

“…In an earlier report we identified specific modifications and substitutions of corticotropin releasing factor (CRF) that led to the discovery of antagonists…”
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Sprague-Dawley rats obtained from different vendors exhibit distinct adrenocorticotropin responses to inflammatory stimuli by Turnbull, A V, Rivier, C L

“…The purpose of this work was to compare the plasma adrenocorticotropin (ACTH), corticosterone and interleukin-6 (IL-6) responses that rats of the outbred…”
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Intracerebroventricular Passive Immunization. II. Intracerebroventricular Infusion of Neuropeptide Antisera Can Inhibit Neuropeptide Signaling in Peripheral Tissues by Turnbull, Andrew V, Rivier, Catherine L

“…The findings of the preceding article suggest that intracerebroventricular (icv) administration of small amounts (5 μl) of antisera to rats may produce…”
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Comparison between the influence of shocks and endotoxemia on the activation of brain cells that contain nitric oxide by Seo, Dong Ook, Lee, Soon, Rivier, Catherine L.

“…We sought to identify the brain circuitry that underlies the stimulatory role of nitric oxide (NO) role on the hypothalamic–pituitary–adrenal (HPA) axis…”
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Intracerebroventricular passive immunization. I. The effect of intracerebroventricular administration of an antiserum to tumor necrosis factor-alpha on the plasma adrenocorticotropin response to lipopolysaccharide in rats by Turnbull, A V, Rivier, C L

“…The present study tested the hypothesis that the cytokine tumor necrosis factor-alpha (TNF-alpha) is an important central nervous system mediator of the rat…”
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Interleukin-1β Regulates Pituitary Follistatin and Inhibin/Activin βB mRNA Levels and Attenuates FSH Secretion in Response to Activin-A by Bilezikjian, Louise M, Turnbull, Andrew V, Corrigan, Anne Z, Blount, Amy L, Rivier, Catherine L, Vale, Wylie W

“…Activins and follistatins regulate all levels of the reproductive axis, including the pituitary where they stimulate and inhibit FSH production, respectively…”
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Influence of Carbon Monoxide, and its Interaction with Nitric Oxide, on the Adrenocorticotropin Hormone Response of the Normal Rat to a Physico-Emotional Stress by Turnbull, Andrew V., Kim, C. Kwon, Lee, Soon, Rivier, Catherine L.

“…We determined whether the gas carbon monoxide (CO) altered the adrenocorticotropin hormone (ACTH) response to mild inescapable electrofootshocks, and whether…”
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Design of Monocyclic (1−3) and Dicyclic (1−3/4−10) Gonadotropin Releasing Hormone (GnRH) Antagonists by Rivier, Jean E, Porter, John, Cervini, Laura A, Lahrichi, Sabine L, Kirby, Dean A, Struthers, R. Scott, Koerber, Steven C, Rivier, Catherine L

“…Careful analysis of the NMR structures of cyclo(4−10)[Ac-Δ3Pro,dFpa,dTrp,Asp,dNal6,Dpr10]GnRH, dicyclo(4−10/5−8)[Ac-dNal1,dCpa2,dTrp3,…”
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Design of Potent Dicyclic (4−10/5−8) Gonadotropin Releasing Hormone (GnRH) Antagonists by Rivier, Jean E, Struthers, R. Scott, Porter, John, Lahrichi, Sabine L, Jiang, Guangcheng, Cervini, Laura A, Ibea, Michel, Kirby, Dean A, Koerber, Steven C, Rivier, Catherine L

“…With the ultimate goal of identifying a consensus bioactive conformation of GnRH antagonists, the compatibility of a number of side chain to side chain bridges…”
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