Search Results - "Rivers, Emanuel P"

Host gene expression classifiers diagnose acute respiratory illness etiology by Tsalik, Ephraim L, Henao, Ricardo, Nichols, Marshall, Burke, Thomas, Ko, Emily R, McClain, Micah T, Hudson, Lori L, Mazur, Anna, Freeman, Debra H, Veldman, Tim, Langley, Raymond J, Quackenbush, Eugenia B, Glickman, Seth W, Cairns, Charles B, Jaehne, Anja K, Rivers, Emanuel P, Otero, Ronny M, Zaas, Aimee K, Kingsmore, Stephen F, Lucas, Joseph, Fowler, Jr, Vance G, Carin, Lawrence, Ginsburg, Geoffrey S, Woods, Christopher W

“…Acute respiratory infections caused by bacterial or viral pathogens are among the most common reasons for seeking medical care. Despite improvements in…”
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Metabolomic derangements are associated with mortality in critically ill adult patients by Rogers, Angela J, McGeachie, Michael, Baron, Rebecca M, Gazourian, Lee, Haspel, Jeffrey A, Nakahira, Kiichi, Fredenburgh, Laura E, Hunninghake, Gary M, Raby, Benjamin A, Matthay, Michael A, Otero, Ronny M, Fowler, Vance G, Rivers, Emanuel P, Woods, Christopher W, Kingsmore, Stephen, Langley, Ray J, Choi, Augustine M K

“…To identify metabolomic biomarkers predictive of Intensive Care Unit (ICU) mortality in adults. Comprehensive metabolomic profiling of plasma at ICU admission…”
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A host-based RT-PCR gene expression signature to identify acute respiratory viral infection by Zaas, Aimee K, Burke, Thomas, Chen, Minhua, McClain, Micah, Nicholson, Bradly, Veldman, Timothy, Tsalik, Ephraim L, Fowler, Vance, Rivers, Emanuel P, Otero, Ronny, Kingsmore, Stephen F, Voora, Deepak, Lucas, Joseph, Hero, Alfred O, Carin, Lawrence, Woods, Christopher W, Ginsburg, Geoffrey S

“…Improved ways to diagnose acute respiratory viral infections could decrease inappropriate antibacterial use and serve as a vital triage mechanism in the event…”
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The influence of early hemodynamic optimization on biomarker patterns of severe sepsis and septic shock by Rivers, Emanuel P, Kruse, James A, Jacobsen, Gordon, Shah, Kant, Loomba, Manisha, Otero, Ronny, Childs, Ed W

“…BACKGROUND:Despite abundant experimental studies of biomarker patterns in early severe sepsis and septic shock, human data are few. Further, the impact of the…”
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Severe Sepsis and Septic Shock: Review of the Literature and Emergency Department Management Guidelines by Nguyen, H. Bryant, Rivers, Emanuel P., Abrahamian, Fredrick M., Moran, Gregory J., Abraham, Edward, Trzeciak, Stephen, Huang, David T., Osborn, Tiffany, Stevens, Dennis, Talan, David A.

“…Severe sepsis and septic shock are as common and lethal as other acute life-threatening conditions that emergency physicians routinely confront such as acute…”
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Counterpoint: Should Lactate Clearance Be Substituted for Central Venous Oxygen Saturation as Goals of Early Severe Sepsis and Septic Shock Therapy? No by Rivers, Emanuel P., MD, MPH, FCCP, Elkin, Ronald, MD, Cannon, Chad M., MD

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Multiplex PCR To Diagnose Bloodstream Infections in Patients Admitted from the Emergency Department with Sepsis by Tsalik, Ephraim L, Jones, Daphne, Nicholson, Bradly, Waring, Lynette, Liesenfeld, Oliver, Park, Lawrence P, Glickman, Seth W, Caram, Lauren B, Langley, Raymond J, van Velkinburgh, Jennifer C, Cairns, Charles B, Rivers, Emanuel P, Otero, Ronny M, Kingsmore, Stephen F, Lalani, Tahaniyat, Fowler, Vance G, Woods, Christopher W

“…Sepsis is caused by a heterogeneous group of infectious etiologies. Early diagnosis and the provision of appropriate antimicrobial therapy correlate with…”
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The Diagnostic Accuracy of Plasma Neutrophil Gelatinase–Associated Lipocalin in the Prediction of Acute Kidney Injury in Emergency Department Patients With Suspected Sepsis by Shapiro, Nathan I., MD, MPH, Trzeciak, Stephen, MD, MPH, Hollander, Judd E., MD, Birkhahn, Robert, MD, Otero, Ronny, MD, Osborn, Tiffany M., MD, Moretti, Eugene, MD, MHSc, Nguyen, H. Bryant, MD, Gunnerson, Kyle, MD, Milzman, David, MD, Gaieski, David F., MD, Goyal, Munish, MD, Cairns, Charles B., MD, Kupfer, Kenneth, PhD, Lee, Seok-Won, PhD, Rivers, Emanuel P., MD, MPH

“…Study objective We assess the diagnostic accuracy of plasma neutrophil gelatinase–associated lipocalin (NGAL) to predict acute kidney injury in emergency…”
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Validation of a host response test to distinguish bacterial and viral respiratory infection by Lydon, Emily C., Henao, Ricardo, Burke, Thomas W., Aydin, Mert, Nicholson, Bradly P., Glickman, Seth W., Fowler, Vance G., Quackenbush, Eugenia B., Cairns, Charles B., Kingsmore, Stephen F., Jaehne, Anja K., Rivers, Emanuel P., Langley, Raymond J., Petzold, Elizabeth, Ko, Emily R., McClain, Micah T., Ginsburg, Geoffrey S., Woods, Christopher W., Tsalik, Ephraim L.

“…Distinguishing bacterial and viral respiratory infections is challenging. Novel diagnostics based on differential host gene expression patterns are promising…”
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Early lactate clearance is associated with biomarkers of inflammation, coagulation, apoptosis, organ dysfunction and mortality in severe sepsis and septic shock by Nguyen, H Bryant, Loomba, Manisha, Yang, James J, Jacobsen, Gordon, Shah, Kant, Otero, Ronny M, Suarez, Arturo, Parekh, Hemal, Jaehne, Anja, Rivers, Emanuel P

“…Lactate clearance, a surrogate for the magnitude and duration of global tissue hypoxia, is used diagnostically, therapeutically and prognostically. This study…”
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Improving Outcomes for Severe Sepsis and Septic Shock: Tools for Early Identification of At-Risk Patients and Treatment Protocol Implementation by Rivers, Emanuel P., MD, MPH, Ahrens, Tom, DNS, RN, CCNS, FAAN

“…Sepsis is a significant problem, and septicemia is the 10th leading cause of death in the United States. Sepsis incidence is increasing, and the mortality rate…”
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Gene expression-based classifiers identify Staphylococcus aureus infection in mice and humans by Ahn, Sun Hee, Tsalik, Ephraim L, Cyr, Derek D, Zhang, Yurong, van Velkinburgh, Jennifer C, Langley, Raymond J, Glickman, Seth W, Cairns, Charles B, Zaas, Aimee K, Rivers, Emanuel P, Otero, Ronny M, Veldman, Tim, Kingsmore, Stephen F, Lucas, Joseph, Woods, Christopher W, Ginsburg, Geoffrey S, Fowler, Jr, Vance G

“…Staphylococcus aureus causes a spectrum of human infection. Diagnostic delays and uncertainty lead to treatment delays and inappropriate antibiotic use. A…”
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Relationship between Central and Peripheral Venous Oxygen Saturation and Lactate Levels: A Prospective Study by Goyal, Nikhil, MD, Taylor, Andrew R., MA, Rivers, Emanuel P., MD

“…Abstract Background Optimization of tissue oxygen delivery to meet consumption demands is important in the resuscitation of critically ill patients. Central…”
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Accelerated Critical Therapy Now in the Emergency Department Using an Early Intervention Team: The Impact of Early Critical Care Consultation for ICU Boarders by Jayaprakash, Namita, Pflaum-Carlson, Jacqueline, Gardner-Gray, Jayna, Hurst, Gina, Kinni, Harish, Tang, Amy, Coba, Victor, Rivers, Emanuel P

“…Evaluate the impact of an emergency department (ED)-based critical care consultation service, hypothesizing early consultation results in shorter hospital…”
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Evaluating the discriminating capacity of cell death (apoptotic) biomarkers in sepsis by Duplessis, Christopher, Gregory, Michael, Frey, Kenneth, Bell, Matthew, Truong, Luu, Schully, Kevin, Lawler, James, Langley, Raymond J, Kingsmore, Stephen F, Woods, Christopher W, Rivers, Emanuel P, Jaehne, Anja K, Quackenbush, Eugenia B, Fowler, Vance G, Tsalik, Ephraim L, Clark, Danielle

“…Sepsis biomarker panels that provide diagnostic and prognostic discrimination in sepsis patients would be transformative to patient care. We assessed the…”
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Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–Deficient Patients by The National Heart, Lung, and Blood Institute PETAL Clinical Trials Network

“…This randomized, placebo-controlled trial examined the potential benefits of vitamin D 3 supplementation in acute critical illness. Among patients with proven…”
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Early High-Dose Vitamin D 3 for Critically Ill, Vitamin D-Deficient Patients by Ginde, Adit A, Brower, Roy G, Caterino, Jeffrey M, Finck, Lani, Banner-Goodspeed, Valerie M, Grissom, Colin K, Hayden, Douglas, Hough, Catherine L, Hyzy, Robert C, Khan, Akram, Levitt, Joseph E, Park, Pauline K, Ringwood, Nancy, Rivers, Emanuel P, Self, Wesley H, Shapiro, Nathan I, Thompson, B Taylor, Yealy, Donald M, Talmor, Daniel

“…Vitamin D deficiency is a common, potentially reversible contributor to morbidity and mortality among critically ill patients. The potential benefits of…”
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Clinical Utility of B-Type Natriuretic Peptide in Early Severe Sepsis and Septic Shock by Rivers, Emanuel P., McCord, James, Otero, Ronny, Jacobsen, Gordon, Loomba, Manisha

“…B-type natriuretic peptide (BNP) has diagnostic, therapeutic, and prognostic utility in critically ill patients. For severe sepsis and septic shock patients in…”
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Centers for Medicare and Medicaid Services Measure Stewards’ Assessment of the Infectious Diseases Society of America’s Position Paper on SEP-1 by Townsend, Sean R, Rivers, Emanuel P, Duseja, Reena

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Rebuttal From Dr Rivers et al by Rivers, Emanuel P., MD, MPH, FCCP, Elkin, Ronald, MD, Cannon, Chad M., MD

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