Search Results - "Rivera‐Mancilla, Eduardo"
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Intracellular pathways of calcitonin gene‐related peptide‐induced relaxation of human coronary arteries: A key role for Gβγ subunit instead of cAMP
Published in British journal of pharmacology (01-08-2024)“…Background and Purpose Calcitonin gene‐related peptide (CGRP) is a potent vasodilator. While its signalling is assumed to be mediated via increases in cAMP,…”
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Streptozotocin‐induced diabetes in rats modifies the role D2, D3 and D4 dopamine receptors play in cardiac sympathetic inhibition
Published in Basic & clinical pharmacology & toxicology (01-10-2022)“…Background Diabetes mellitus is associated with abnormalities in peripheral/central catecholaminergic systems, including changes in catecholamine levels and…”
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Differential cardiac sympatho‐inhibitory responses produced by the agonists B‐HT 933, quinpirole and immepip in normoglycaemic and diabetic pithed rats
Published in Clinical and experimental pharmacology & physiology (01-08-2018)“…Summary This study compared the cardiac sympatho‐inhibitory responses produced by agonists at α2‐adrenergic (B‐HT 933), dopamine D2‐like (quinpirole) and…”
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Blockade of 5‐HT2 receptors with sarpogrelate uncovers 5‐HT7 receptors inhibiting the tachycardic sympathetic drive in pithed rats
Published in Clinical and experimental pharmacology & physiology (01-03-2020)“…Our group has previously shown in pithed rats that the cardiac sympathetic drive, which produces tachycardic responses, is inhibited by 5‐HT via the activation…”
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Metabolic Aspects of Migraine: Association With Obesity and Diabetes Mellitus
Published in Frontiers in neurology (09-06-2021)“…Migraine is a disabling neurovascular disorder, characterized by moderate to severe unilateral headaches, nausea, photophobia, and/or phonophobia, with a…”
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Prolactin and oxytocin: potential targets for migraine treatment
Published in Journal of headache and pain (27-03-2023)“…Migraine is a severe neurovascular disorder of which the pathophysiology is not yet fully understood. Besides the role of inflammatory mediators that interact…”
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Functional Analysis of TRPA1, TRPM3, and TRPV1 Channels in Human Dermal Arteries and Their Role in Vascular Modulation
Published in Pharmaceuticals (Basel, Switzerland) (25-01-2024)“…Transient receptor potential (TRP) channels are pivotal in modulating vascular functions. In fact, topical application of cinnamaldehyde or capsaicin (TRPA1…”
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Blockade of 5-HT 2 receptors with sarpogrelate uncovers 5-HT 7 receptors inhibiting the tachycardic sympathetic drive in pithed rats
Published in Clinical and experimental pharmacology & physiology (01-03-2020)“…Our group has previously shown in pithed rats that the cardiac sympathetic drive, which produces tachycardic responses, is inhibited by 5-HT via the activation…”
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The role of α1- and α2-adrenoceptor subtypes in the vasopressor responses induced by dihydroergotamine in ritanserin-pretreated pithed rats
Published in Journal of headache and pain (11-10-2017)“…Background Dihydroergotamine (DHE) is an acute antimigraine agent that displays affinity for dopamine D 2 -like receptors, serotonin 5-HT 1/2 receptors and α 1…”
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CGRP inhibitors for migraine prophylaxis: a safety review
Published in Expert opinion on drug safety (02-10-2020)“…Since calcitonin gene-related peptide (CGRP) plays an important role in the pathophysiology of migraine via the activation of the trigeminovascular system, the…”
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Streptozotocin‐induced diabetes in rats modifies the role D 2 , D 3 and D 4 dopamine receptors play in cardiac sympathetic inhibition
Published in Basic & clinical pharmacology & toxicology (01-10-2022)“…Abstract Background Diabetes mellitus is associated with abnormalities in peripheral/central catecholaminergic systems, including changes in catecholamine…”
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Headache onset after vaccination against SARS-CoV-2: a systematic literature review and meta-analysis
Published in Journal of headache and pain (31-03-2022)“…Background Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are used to reduce the risk of developing Coronavirus Disease 2019…”
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The role of purinergic P2Y12 and P2Y13 receptors in ADPβS-induced inhibition of the cardioaccelerator sympathetic drive in pithed rats
Published in Purinergic signalling (01-03-2020)“…ATP is a cotransmitter released with other neurotransmitters from sympathetic nerves, where it stimulates purinergic receptors. Purinergic adenosine P 1…”
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Activation of Dopamine D3 Receptor Subtypes Inhibits the Neurogenic Systemic Vasodilation Induced by Stimulation of the Perivascular CGRPergic Discharge
Published in ACS chemical neuroscience (21-08-2019)“…The sensory nervous system controls cardiovascular homeostasis via capsaicin-sensitive neurons that release calcitonin gene-related peptide (CGRP), which…”
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The role of purinergic P2Y 12 and P2Y 13 receptors in ADPβS-induced inhibition of the cardioaccelerator sympathetic drive in pithed rats
Published in Purinergic signalling (01-03-2020)“…ATP is a cotransmitter released with other neurotransmitters from sympathetic nerves, where it stimulates purinergic receptors. Purinergic adenosine P…”
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Activation of Dopamine D 3 Receptor Subtypes Inhibits the Neurogenic Systemic Vasodilation Induced by Stimulation of the Perivascular CGRPergic Discharge
Published in ACS chemical neuroscience (21-08-2019)“…The sensory nervous system controls cardiovascular homeostasis via capsaicin-sensitive neurons that release calcitonin gene-related peptide (CGRP), which…”
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Pharmacological evidence that histamine H3 receptors inhibit the vasodepressor responses by selective stimulation of the rat perivascular sensory CGRPergic outflow
Published in European journal of pharmacology (05-05-2015)“…This study has investigated whether pharmacological activation of Gi/o coupled histamine H3/H4 receptors inhibits the rat vasodepressor sensory outflow. For…”
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The role of α^sub 1^- and α^sub 2^-adrenoceptor subtypes in the vasopressor responses induced by dihydroergotamine in ritanserin-pretreated pithed rats
Published in Journal of headache and pain (01-10-2017)“…Dihydroergotamine (DHE) is an acute antimigraine agent that displays affinity for dopamine D2-like receptors, serotonin 5-HT1/2 receptors and…”
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Journal Article -
20
The role of α 1 - and α 2 -adrenoceptor subtypes in the vasopressor responses induced by dihydroergotamine in ritanserin-pretreated pithed rats
Published in Journal of headache and pain (11-10-2017)“…Dihydroergotamine (DHE) is an acute antimigraine agent that displays affinity for dopamine D -like receptors, serotonin 5-HT receptors and α /α -adrenoceptors…”
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