Search Results - "Rivera, Brianna M."

CSF1R inhibitors induce a sex-specific resilient microglial phenotype and functional rescue in a tauopathy mouse model by Johnson, Noah R., Yuan, Peng, Castillo, Erika, Lopez, T. Peter, Yue, Weizhou, Bond, Annalise, Rivera, Brianna M., Sullivan, Miranda C., Hirouchi, Masakazu, Giles, Kurt, Aoyagi, Atsushi, Condello, Carlo

“…Microglia are central to pathogenesis in many neurological conditions. Drugs targeting colony-stimulating factor-1 receptor (CSF1R) to block microglial…”
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Emergence of distinct and heterogeneous strains of amyloid beta with advanced Alzheimer's disease pathology in Down syndrome by Maxwell, Alison M, Yuan, Peng, Rivera, Brianna M, Schaaf, Wilder, Mladinov, Mihovil, Prasher, Vee P, Robinson, Andrew C, DeGrado, William F, Condello, Carlo

“…Amyloid beta (Aβ) is thought to play a critical role in the pathogenesis of Alzheimer's disease (AD). Prion-like Aβ polymorphs, or "strains", can have varying…”
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Guam ALS-PDC is a distinct double-prion disorder featuring both tau and Aβ prions by Condello, Carlo, Ayers, Jacob I, Dalgard, Clifton L, Garcia Garcia, M Madhy, Rivera, Brianna M, Seeley, William W, Perl, Daniel P, Prusiner, Stanley B

“…The amyotrophic lateral sclerosis-parkinsonism dementia complex (ALS-PDC) of Guam is an endemic neurodegenerative disease that features widespread tau tangles,…”
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Amyloid β Proteoforms Elucidated by Quantitative LC/MS in the 5xFAD Mouse Model of Alzheimer’s Disease by Kandi, Soumya, Cline, Erika N., Rivera, Brianna M., Viola, Kirsten L., Zhu, Jiuhe, Condello, Carlo, LeDuc, Richard D., Klein, William L., Kelleher, Neil L., Patrie, Steven M.

“…Numerous Aβ proteoforms, identified in the human brain, possess differential neurotoxic and aggregation propensities. These proteoforms contribute in unknown…”
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AGED ALZHEIMER’S DISEASE BRAINS EXHIBIT NUMEROUS Aβ BUT ONLY FEW TAU PRIONS by Condello, Carlo, Aoyagi, Atsushi, Stöhr, Jan, Lee, Joanne C., Rivera, Brianna M., Woerman, Amanda L., Halliday, Glenda M., van Duinen, Sjoerd, Ingelsson, Martin, Lannfelt, Lars, Graff, Caroline, Bird, Thomas D., Dirk Keene, C., Seeley, William W., DeGrado, William F., Prusiner, Stanley B.

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P4‐233: AGED ALZHEIMER'S DISEASE BRAINS EXHIBIT NUMEROUS Aβ BUT ONLY FEW TAU PRIONS by Condello, Carlo, Aoyagi, Atsushi, Stöhr, Jan, Lee, Joanne C., Rivera, Brianna M., Woerman, Amanda L., Halliday, Glenda M., Duinen, Sjoerd, Ingelsson, Martin, Lannfelt, Lars, Graff, Caroline, Bird, Thomas D., Dirk Keene, C., Seeley, William W., DeGrado, William F., Prusiner, Stanley B.

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