Design and scale-up of chemical reactors for nanoparticle precipitation

In recent years there has been a growing interest in production on an industrial scale of particles with size in the sub‐micron range (40‐200 nm). This can be done by controlling particle formation in order to nucleate very small particles and by tailoring the particle surface in order to avoid part...

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Bibliographic Details
Published in:	AIChE journal Vol. 52; no. 5; pp. 1877 - 1887
Main Authors:	Marchisio, Daniele L., Rivautella, Liliana, Barresi, Antonello A.
Format:	Journal Article
Language:	English
Published:	Hoboken Wiley Subscription Services, Inc., A Wiley Company 01-05-2006 Wiley Subscription Services American Institute of Chemical Engineers
Subjects:	Applied sciences barium sulfate CFD Chemical engineering confined impinging jet reactor Exact sciences and technology Fluid dynamics modeling Nanoparticles precipitation Reactors scale-up CFD barium sulfate Computational fluid dynamics Nanoparticle Scale effect scale-up confined impinging jet reactor Modeling Turbulent mixing Aggregation Design Extrapolation precipitation Chemical reactor nanoparticles Production
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Summary:	In recent years there has been a growing interest in production on an industrial scale of particles with size in the sub‐micron range (40‐200 nm). This can be done by controlling particle formation in order to nucleate very small particles and by tailoring the particle surface in order to avoid particle aggregation and produce stable suspensions. In this work we focus on the role of turbulent mixing on particle formation in confined impinging jet reactors. In particular, we show how computational fluid dynamics and simple precipitation models could be used to derive scale‐up criteria for the production of nanoparticles. © 2006 American Institute of Chemical Engineers AIChE J, 2006
Bibliography:	Ministry of Education, University and Research ark:/67375/WNG-T6QPHZ2N-6 istex:637AC38310B8EAF2DBCA33A4C4EF34F5B7486789 ArticleID:AIC10786 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23
ISSN:	0001-1541 1547-5905
DOI:	10.1002/aic.10786