Search Results - "Rivas, Paulo"

Naturally acquired antibody response to a Plasmodium falciparum chimeric vaccine candidate GMZ2.6c and its components (MSP-3, GLURP, and Pfs48/45) in individuals living in Brazilian malaria-endemic areas by Baptista, Barbara Oliveira, de Souza, Ana Beatriz Lopes, Riccio, Evelyn Kety Pratt, Bianco-Junior, Cesare, Totino, Paulo Renato Rivas, Martins da Silva, João Hermínio, Theisen, Michael, Singh, Susheel Kumar, Amoah, Linda Eva, Ribeiro-Alves, Marcelo, Souza, Rodrigo Medeiros, Lima-Junior, Josué Costa, Daniel-Ribeiro, Cláudio Tadeu, Pratt-Riccio, Lilian Rose

“…The GMZ2.6c malaria vaccine candidate is a multi-stage Plasmodium falciparum chimeric protein which contains a fragment of the sexual-stage Pfs48/45-6C protein…”
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Recombinant Plasmodium vivax circumsporozoite surface protein allelic variants: antibody recognition by individuals from three communities in the Brazilian Amazon by Soares, Isabela Ferreira, López-Camacho, César, Rodrigues-da-Silva, Rodrigo Nunes, da Silva Matos, Ada, de Oliveira Baptista, Barbara, Totino, Paulo Renato Rivas, de Souza, Rodrigo Medeiros, Harrison, Kate, Gimenez, Alba Marina, de Freitas, Elisângela Oliveira, Kim, Young Chan, Oliveira-Ferreira, Joseli, Daniel-Ribeiro, Cláudio Tadeu, Reyes-Sandoval, Arturo, Pratt-Riccio, Lilian Rose, Lima-Junior, Josué da Costa

“…Circumsporozoite protein (CSP) variants of P. vivax , besides having variations in the protein repetitive portion, can differ from each other in aspects such…”
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Plasmodium vivax metacaspase 1 (PvMCA1) catalytic domain is conserved in field isolates from Brazilian Amazon by de Souza, Hugo Amorim dos Santos, Escafa, Victor Fernandes, Blanco, Carolina Moreira, Baptista, Bárbara de Oliveira, de Barros, Jenifer Peixoto, Riccio, Evelyn Ketty Pratt, Rodrigues, Aline Beatriz Mello, Melo, Gisely Cardoso de, Lacerda, Marcus Vinícius Guimarães de, de Souza, Rodrigo Medeiros, Lima-Junior, Josué da Costa, Guimarães, Ana Carolina Ramos, da Mota, Fabio Faria, da Silva, João Hermínio Martins, Daniel-Ribeiro, Cláudio Tadeu, Pratt-Riccio, Lilian Rose, Totino, Paulo Renato Rivas

“…In the present study, we investigated the genetic diversity of Plasmodium vivax metacaspase 1 ( Pv MCA1) catalytic domain in two municipalities of the main…”
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Antibody Responses Against Plasmodium vivax TRAP Recombinant and Synthetic Antigens in Naturally Exposed Individuals From the Brazilian Amazon by Matos, Ada da Silva, Rodrigues-da-Silva, Rodrigo Nunes, Soares, Isabela Ferreira, Baptista, Barbara de Oliveira, de Souza, Rodrigo Medeiros, Bitencourt-Chaves, Lana, Totino, Paulo Renato Rivas, Sánchez-Arcila, Juan Camilo, Daniel-Ribeiro, Cláudio Tadeu, López-Camacho, César, Reyes-Sandoval, Arturo, Pratt-Riccio, Lilian Rose, Lima-Junior, Josué da Costa

“…Thrombospondin-related adhesive protein (TRAP) is essential for sporozoite motility and the invasion of mosquitoes' salivary gland and vertebrate's hepatocyte…”
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Eryptosis of non-parasitized erythrocytes is related to anemia in Plasmodium berghei low parasitema malaria of Wistar rats by Totino, Paulo Renato Rivas, de Souza, Hugo Amorim dos Santos, Correa, Edmar Henrique Costa, Daniel-Ribeiro, Cláudio Tadeu, Ferreira-da-Cruz, Maria de Fátima

“…It is known that premature elimination of non-parasitized RBCs (nRBCs) plays an important role in the pathogenesis of malarial anemia, in which suicidal death…”
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Chloroquine and mefloquine resistance profiles are not related to the circumsporozoite protein (CSP) VK210 subtypes in field isolates of Plasmodium vivax from Manaus, Brazilian Amazon by Pratt-Riccio, Lilian Rose, Baptista, Bárbara de Oliveira, Torres, Vanessa Rodrigues, Bianco-Junior, Cesare, Perce-Da-Silva, Daiana de Souza, Riccio, Evelyn Kety Pratt, Lima-Junior, Josué da Costa, Totino, Paulo Renato Rivas, Cassiano, Gustavo Capatti, Storti-Melo, Luciane Moreno, Machado, Ricardo Luiz Dantas, de Oliveira-Ferreira, Joseli, Banic, Dalma Maria, Carvalho, Leonardo José de Moura, Daniel-Ribeiro, Cláudio Tadeu

“…The central repetitive region (CRR) of the Plasmodium vivax circumsporozoite surface protein (CSP) is composed of a repetitive sequence that is characterised…”
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Refractoriness of eryptotic red blood cells to Plasmodium falciparum infection: a putative host defense mechanism limiting parasitaemia by Totino, Paulo Renato Rivas, Daniel-Ribeiro, Cláudio Tadeu, Ferreira-da-Cruz, Maria de Fátima

“…Recently, we have described that apoptosis-like process of red blood cells (RBC) - eryptosis - in malaria is not restricted to parasitized cells, occurring…”
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Detection of Signal Regulatory Protein α in Saimiri sciureus (Squirrel Monkey) by Anti-Human Monoclonal Antibody by de Souza, Hugo Amorim Dos Santos, Costa-Correa, Edmar Henrique, Bianco-Junior, Cesare, Andrade, Márcia Cristina Ribeiro, Lima-Junior, Josué da Costa, Pratt-Riccio, Lilian Rose, Daniel-Ribeiro, Cláudio Tadeu, Totino, Paulo Renato Rivas

“…Non-human primates (NHP) are suitable models for studying different aspects of the human system, including pathogenesis and protective immunity to many…”
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Plasmodium falciparum: Erythrocytic stages die by autophagic-like cell death under drug pressure by Totino, Paulo Renato Rivas, Daniel-Ribeiro, Cláudio Tadeu, Corte-Real, Suzana, Ferreira-da-Cruz, Maria de Fátima

“…It has been reported that an apoptotic cell death process can occur with protozoans, but no consensus on Plasmodium susceptibility to apoptosis was reached…”
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Plasmodium falciparum, but not P. vivax, can induce erythrocytic apoptosis by Totino, Paulo Renato Rivas, Magalhães, Aline das Dores, Alves, Eliana Brasil, Costa, Monica Regina Farias, de Lacerda, Marcus Vinícius Guimarães, Daniel-Ribeiro, Cláudio Tadeu, Ferreira-da-Cruz, Maria de Fátima

“…Apoptosis can occur in red blood cells (RBC) and seems to be involved in hematologic disorders related to many diseases. In malaria it is known that…”
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Apoptosis of non-parasitised red blood cells in Plasmodium yoelii malaria by Totino, Paulo Renato Rivas, Pinna, Raquel Alves, Oliveira, Ana Cecilia Amado Xavier de, Banic, Dalma Maria, Daniel-Ribeiro, Cláudio Tadeu, Ferreira-da-Cruz, Maria de Fátima

“…Recently, while studying erythrocytic apoptosis during Plasmodium yoelii infection, we observed an increase in the levels of non-parasitised red blood cell…”
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Eryptosis as a New Insight in Malaria Pathogenesis by Scovino, Aline Miranda, Totino, Paulo Renato Rivas, Morrot, Alexandre

“…Eryptosis is a programmed cell death-like process that occurs in red blood cells. Although the red blood cells are anucleated, there are similarities between…”
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Asymptomatic infection in individuals from the municipality of Barcelos (Brazilian Amazon) is not associated with the anti-Plasmodium falciparum glycosylphosphatidylinositol antibody response by Gomes, Larissa Rodrigues, Totino, Paulo Renato Rivas, Sanchez, Maria Carmen Arroyo, Daniel, Elsa Paula da Silva Kaingona, Macedo, Cristiana Santos de, Fortes, Filomeno, Coura, José Rodrigues, Santi, Silvia Maria Di, Werneck, Guilherme Loureiro, Suárez-Mutis, Martha Cecilia, Ferreira-da-Cruz, Maria de Fátima, Daniel-Ribeiro, Cláudio Tadeu

“…Anti-glycosylphosphatidylinositol (GPI) antibodies (Abs) may reflect and mediate, at least partially, anti-disease immunity in malaria by neutralising the…”
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Antibodies against the Plasmodium falciparum glutamate-rich protein from naturally exposed individuals living in a Brazilian malaria-endemic area can inhibit in vitro parasite growth by Pratt-Riccio, Lilian Rose, Bianco, Jr, Cesare, Totino, Paulo Renato Rivas, Perce-Da-Silva, Daiana De Souza, Silva, Luciene Aquino, Riccio, Evelyn Kety Pratt, Ennes-Vidal, Vítor, Neves-Ferreira, Ana Gisele Costa, Perales, Jonas, Da Rocha, Surza Lucia Gonçalves, Dias-Da-Silva, Fabrício, Ferreira-da-Cruz, Maria de Fátima, Daniel-Ribeiro, Cláudio Tadeu, De Oliveira-Ferreira, Joseli, Theisen, Michael, Carvalho, Leonardo José De Moura, Banic, Dalma Maria

“…The glutamate-rich protein (GLURP) is an exoantigen expressed in all stages of the Plasmodium falciparum life cycle in humans. Anti-GLURP antibodies can…”
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Characterization of T and B cell epitopes in PvCyRPA by studying the naturally acquired immune response in Brazilian Amazon communities by Soares, Isabela Ferreira, de Oliveira Baptista, Barbara, da Silva Matos, Ada, Rodrigues-da-Silva, Rodrigo Nunes, Kujbida Junior, Mario Antonio, Albrecht, Letusa, Rodolphi, Cinthia Magalhães, Scopel, Kézia Katiani Gorza, Alencar, Ana Luiza Carneiro, de Souza, Rodrigo Medeiros, dos Santos de Souza, Hugo Amorim, Riccio, Evelyn Kety Pratt, de Barros, Jenifer Peixoto, Totino, Paulo Renato Rivas, Daniel-Ribeiro, Cláudio Tadeu, Pratt-Riccio, Lilian Rose, Lima-Junior, Josué da Costa

“…Plasmodium vivax , a challenging species to eliminate, causes millions of malaria cases globally annually. Developing an effective vaccine is crucial in the…”
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Construction, Expression, and Evaluation of the Naturally Acquired Humoral Immune Response against Plasmodium vivax RMC-1, a Multistage Chimeric Protein by Matos, Ada da Silva, Soares, Isabela Ferreira, Baptista, Barbara de Oliveira, de Souza, Hugo Amorim Dos Santos, Chaves, Lana Bitencourt, Perce-da-Silva, Daiana de Souza, Riccio, Evelyn Kety Pratt, Albrecht, Letusa, Totino, Paulo Renato Rivas, Rodrigues-da-Silva, Rodrigo Nunes, Daniel-Ribeiro, Cláudio Tadeu, Pratt-Riccio, Lilian Rose, Lima-Junior, Josué da Costa

“…The PvCelTOS, PvCyRPA, and Pvs25 proteins play important roles during the three stages of the lifecycle. In this study, we designed and expressed a recombinant…”
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Immunogenicity of synthetic peptide constructs based on PvMSP9E795-A808, a linear B-cell epitope of the P. vivax Merozoite Surface Protein-9 by Rodrigues-da-Silva, Rodrigo Nunes, Correa-Moreira, Daniely, Soares, Isabela Ferreira, de-Luca, Paula Melo, Totino, Paulo Renato Rivas, Morgado, Fernanda Nazaré, Oliveira Henriques, Maria das Graças de, Peixoto Candea, André Luis, Singh, Balwan, Galinski, Mary R., Moreno, Alberto, Oliveira-Ferreira, Joseli, Lima-Junior, Josué da Costa

“…•PvMSp9E795-A808 synthetic constructs were immunogenic in mice.•IgG1, IgG2a and IgG2b were prevalent in humoral response induced by synthetic peptides.•T-cell…”
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Immunogenicity of PvCyRPA, PvCelTOS and Pvs25 chimeric recombinant protein of Plasmodium vivax in murine model by Matos, Ada da Silva, Soares, Isabela Ferreira, Rodrigues-da-Silva, Rodrigo Nunes, Rodolphi, Cinthia Magalhães, Albrecht, Letusa, Donassolo, Rafael Amaral, Lopez-Camacho, Cesar, Ano Bom, Ana Paula Dinis, Neves, Patrícia Cristina da Costa, Conte, Fernando de Paiva, Pratt-Riccio, Lilian Rose, Daniel-Ribeiro, Cláudio Tadeu, Totino, Paulo Renato Rivas, Lima-Junior, Josué da Costa

“…In the Americas, is the predominant causative species of malaria, a debilitating and economically significant disease. Due to the complexity of the malaria…”
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Plasmodium vivax ookinete surface protein (Pvs25) is highly conserved among field isolates from five different regions of the Brazilian Amazon by Chaves, Lana Bitencourt, Perce-da-Silva, Daiana de Souza, Totino, Paulo Renato Rivas, Riccio, Evelyn Kety Pratt, Baptista, Barbara de Oliveira, de Souza, Ana Beatriz Lopes, Rodrigues-da-Silva, Rodrigo Nunes, Machado, Ricardo Luiz Dantas, de Souza, Rodrigo Medeiros, Daniel-Ribeiro, Cláudio Tadeu, Banic, Dalma Maria, Pratt-Riccio, Lilian Rose, Lima-Junior, Josué da Costa

“…The Plasmodium vivax Ookinete Surface Protein (Pvs25) is one of the leading malaria Transmission-Blocking Vaccine candidates based on its high immunogenicity…”
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Immunogenicity of synthetic peptide constructs based on PvMSP9 E795-A808 , a linear B-cell epitope of the P. vivax Merozoite Surface Protein-9 by Rodrigues-da-Silva, Rodrigo Nunes, Correa-Moreira, Daniely, Soares, Isabela Ferreira, de-Luca, Paula Melo, Totino, Paulo Renato Rivas, Morgado, Fernanda Nazaré, Oliveira Henriques, Maria das Graças de, Peixoto Candea, André Luis, Singh, Balwan, Galinski, Mary R, Moreno, Alberto, Oliveira-Ferreira, Joseli, Lima-Junior, Josué da Costa

“…Plasmodium vivax Merozoite Surface Protein-9 (PvMSP-9) is a malaria vaccine candidate naturally immunogenic in humans and able to induce high antibody titers…”
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