Search Results - "Rivas, A."

Significant sparse polygenic risk scores across 813 traits in UK Biobank by Tanigawa, Yosuke, Qian, Junyang, Venkataraman, Guhan, Justesen, Johanne Marie, Li, Ruilin, Tibshirani, Robert, Hastie, Trevor, Rivas, Manuel A

“…We present a systematic assessment of polygenic risk score (PRS) prediction across more than 1,500 traits using genetic and phenotype data in the UK Biobank…”
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Two-dimensional density-matrix topological fermionic phases: topological Uhlmann numbers by Viyuela, O, Rivas, A, Martin-Delgado, M A

“…We construct a topological invariant that classifies density matrices of symmetry-protected topological orders in two-dimensional fermionic systems. As it is…”
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Early Adaptation and Acquired Resistance to CDK4/6 Inhibition in Estrogen Receptor-Positive Breast Cancer by Herrera-Abreu, Maria Teresa, Palafox, Marta, Asghar, Uzma, Rivas, Martín A, Cutts, Rosalind J, Garcia-Murillas, Isaac, Pearson, Alex, Guzman, Marta, Rodriguez, Olga, Grueso, Judit, Bellet, Meritxell, Cortés, Javier, Elliott, Richard, Pancholi, Sunil, Baselga, José, Dowsett, Mitch, Martin, Lesley-Ann, Turner, Nicholas C, Serra, Violeta

“…Small-molecule inhibitors of the CDK4/6 cell-cycle kinases have shown clinical efficacy in estrogen receptor (ER)-positive metastatic breast cancer, although…”
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Uhlmann phase as a topological measure for one-dimensional fermion systems by Viyuela, O, Rivas, A, Martin-Delgado, M A

“…We introduce the Uhlmann geometric phase as a tool to characterize symmetry-protected topological phases in one-dimensional fermion systems, such as…”
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A cross-population atlas of genetic associations for 220 human phenotypes by Sakaue, Saori, Kanai, Masahiro, Tanigawa, Yosuke, Karjalainen, Juha, Kurki, Mitja, Koshiba, Seizo, Narita, Akira, Konuma, Takahiro, Yamamoto, Kenichi, Akiyama, Masato, Ishigaki, Kazuyoshi, Suzuki, Akari, Suzuki, Ken, Obara, Wataru, Yamaji, Ken, Takahashi, Kazuhisa, Asai, Satoshi, Takahashi, Yasuo, Suzuki, Takao, Shinozaki, Nobuaki, Yamaguchi, Hiroki, Minami, Shiro, Murayama, Shigeo, Yoshimori, Kozo, Nagayama, Satoshi, Obata, Daisuke, Higashiyama, Masahiko, Masumoto, Akihide, Koretsune, Yukihiro, Ito, Kaoru, Terao, Chikashi, Yamauchi, Toshimasa, Komuro, Issei, Kadowaki, Takashi, Tamiya, Gen, Yamamoto, Masayuki, Nakamura, Yusuke, Kubo, Michiaki, Murakami, Yoshinori, Yamamoto, Kazuhiko, Kamatani, Yoichiro, Palotie, Aarno, Rivas, Manuel A., Daly, Mark J., Matsuda, Koichi, Okada, Yukinori

“…Current genome-wide association studies do not yet capture sufficient diversity in populations and scope of phenotypes. To expand an atlas of genetic…”
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Chemistry and microstructure of C-supported Ru catalyst nanoparticles: A correlative study by Rivas, Nicolás A. Rivas, Manjón, Alba Garzón, Vega-Paredes, Miquel, Kim, Se-Ho, Gault, Baptiste, Jun, Hosun, Jung, Chanwon, Berova, Viktoriya, Hengge, Katharina, Jurzinsky, Tilman, Scheu, Christina

“…•3-D visualization of impurities within Ru nanoparticles used as catalysts for fuel cell applications.•Interpretation of atom probe results by electron…”
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Density-matrix Chern insulators: Finite-temperature generalization of topological insulators by Rivas, A., Viyuela, O., Martin-Delgado, M. A.

“…Thermal noise can destroy topological insulators (Tl). However, we demonstrate how TIs can be made stable in dissipative systems. To that aim, we introduce the…”
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Effects of heat stress on animal physiology, metabolism, and meat quality: A review by Gonzalez-Rivas, Paula A., Chauhan, Surinder S., Ha, Minh, Fegan, Narelle, Dunshea, Frank R., Warner, Robyn D.

“…Heat stress is one of the most stressful events in the life of livestock with harmful consequences for animal health, productivity and product quality…”
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Genetics of 35 blood and urine biomarkers in the UK Biobank by Sinnott-Armstrong, Nasa, Tanigawa, Yosuke, Amar, David, Mars, Nina, Benner, Christian, Aguirre, Matthew, Venkataraman, Guhan Ram, Wainberg, Michael, Ollila, Hanna M., Kiiskinen, Tuomo, Havulinna, Aki S., Pirruccello, James P., Qian, Junyang, Shcherbina, Anna, Rodriguez, Fatima, Assimes, Themistocles L., Agarwala, Vineeta, Tibshirani, Robert, Hastie, Trevor, Ripatti, Samuli, Pritchard, Jonathan K., Daly, Mark J., Rivas, Manuel A.

“…Clinical laboratory tests are a critical component of the continuum of care. We evaluate the genetic basis of 35 blood and urine laboratory measurements in the…”
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EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop by Béguelin, Wendy, Rivas, Martín A., Calvo Fernández, María T., Teater, Matt, Purwada, Alberto, Redmond, David, Shen, Hao, Challman, Matt F., Elemento, Olivier, Singh, Ankur, Melnick, Ari M.

“…The EZH2 histone methyltransferase is required for B cells to form germinal centers (GC). Here we show that EZH2 mediates GC formation through repression of…”
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The C:N:P stoichiometry of organisms and ecosystems in a changing world: A review and perspectives by Sardans, J., Rivas-Ubach, A., Peñuelas, J.

“…This study examined the literature in ISI Web of Science to identify the effects that the main drivers of global change have on the nutrient concentrations and…”
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Association of accelerometer-derived sleep measures with lifetime psychiatric diagnoses: A cross-sectional study of 89,205 participants from the UK Biobank by Wainberg, Michael, Jones, Samuel E, Beaupre, Lindsay Melhuish, Hill, Sean L, Felsky, Daniel, Rivas, Manuel A, Lim, Andrew S P, Ollila, Hanna M, Tripathy, Shreejoy J

“…Sleep problems are both symptoms of and modifiable risk factors for many psychiatric disorders. Wrist-worn accelerometers enable objective measurement of sleep…”
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Time trajectories in the transcriptomic response to exercise - a meta-analysis by Amar, David, Lindholm, Malene E., Norrbom, Jessica, Wheeler, Matthew T., Rivas, Manuel A., Ashley, Euan A.

“…Exercise training prevents multiple diseases, yet the molecular mechanisms that drive exercise adaptation are incompletely understood. To address this, we…”
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Clinical outcome and prognostic factors of patients with Richter syndrome: real‐world study of the Spanish Chronic Lymphocytic Leukemia Study Group (GELLC) by Abrisqueta, Pau, Delgado, Julio, Alcoceba, Miguel, Oliveira, Ana Carla, Loscertales, Javier, Hernández‐Rivas, Jose A., Ferrà, Christelle, Cordoba, Raul, Yáñez, Lucrecia, Medina, Angeles, Motlló, Cristina, Iacoboni, Gloria, Villacampa, Guillermo, González, Marcos, Bosch, Francesc

“…Summary Richter syndrome (RS) is an uncommon evolution of chronic lymphocytic leukaemia (CLL) with a dismal prognosis. Clinical‐biological features predicting…”
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A fast and scalable framework for large-scale and ultrahigh-dimensional sparse regression with application to the UK Biobank by Qian, Junyang, Tanigawa, Yosuke, Du, Wenfei, Aguirre, Matthew, Chang, Chris, Tibshirani, Robert, Rivas, Manuel A, Hastie, Trevor

“…The UK Biobank is a very large, prospective population-based cohort study across the United Kingdom. It provides unprecedented opportunities for researchers to…”
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Significant shared heritability underlies suicide attempt and clinically predicted probability of attempting suicide by Ruderfer, Douglas M., Walsh, Colin G., Aguirre, Matthew W., Tanigawa, Yosuke, Ribeiro, Jessica D., Franklin, Joseph C., Rivas, Manuel A.

“…Suicide accounts for nearly 800,000 deaths per year worldwide with rates of both deaths and attempts rising. Family studies have estimated substantial…”
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Antimicrobial potential of macro and microalgae against pathogenic and spoilage microorganisms in food by Pina-Pérez, M.C., Rivas, A., Martínez, A., Rodrigo, D.

“…•Algae is a promising genera with valuable application in human feeding.•Antimicrobial potential of bioactives from algae remain as a niche of research.•Novel…”
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TNFα-Induced Mucin 4 Expression Elicits Trastuzumab Resistance in HER2-Positive Breast Cancer by Mercogliano, María F, De Martino, Mara, Venturutti, Leandro, Rivas, Martín A, Proietti, Cecilia J, Inurrigarro, Gloria, Frahm, Isabel, Allemand, Daniel H, Deza, Ernesto Gil, Ares, Sandra, Gercovich, Felipe G, Guzmán, Pablo, Roa, Juan C, Elizalde, Patricia V, Schillaci, Roxana

“…Although trastuzumab administration improved the outcome of HER2-positive breast cancer patients, resistance events hamper its clinical benefits. We…”
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The power of gene-based rare variant methods to detect disease-associated variation and test hypotheses about complex disease by Moutsianas, Loukas, Agarwala, Vineeta, Fuchsberger, Christian, Flannick, Jason, Rivas, Manuel A, Gaulton, Kyle J, Albers, Patrick K, McVean, Gil, Boehnke, Michael, Altshuler, David, McCarthy, Mark I

“…Genome and exome sequencing in large cohorts enables characterization of the role of rare variation in complex diseases. Success in this endeavor, however,…”
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Disentangling the Anacondas: Revealing a New Green Species and Rethinking Yellows by Rivas, Jesús A, De La Quintana, Paola, Mancuso, Marco, Pacheco, Luis F, Rivas, Gilson A, Mariotto, Sandra, Salazar-Valenzuela, David, Baihua, Marcelo Tepeña, Baihua, Penti, Burghardt, Gordon M, Vonk, Freek J, Hernandez, Emil, García-Pérez, Juán Elías, Fry, Bryan G, Corey-Rivas, Sarah

“…Anacondas, genus Eunectes, are a group of aquatic snakes with a wide distribution in South America. The taxonomic status of several species has been uncertain…”
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