Search Results - "Rivard, Nathalie"

G-quadruplex located in the 5′UTR of the BAG-1 mRNA affects both its cap-dependent and cap-independent translation through global secondary structure maintenance by Jodoin, Rachel, Carrier, Julie C, Rivard, Nathalie, Bisaillon, Martin, Perreault, Jean-Pierre

“…Abstract The anti-apoptotic BAG-1 protein isoforms are known to be overexpressed in colorectal tumors and are considered to be potential therapeutic targets…”
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TIRAP, TRAM, and Toll-Like Receptors: The Untold Story by Lannoy, Valérie, Côté-Biron, Anthony, Asselin, Claude, Rivard, Nathalie

“…Toll-like receptors (TLRs) are the most studied receptors among the pattern recognition receptors (PRRs). They act as microbial sensors, playing major roles in…”
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Cathepsin B promotes colorectal tumorigenesis, cell invasion, and metastasis by Bian, Benjamin, Mongrain, Sébastien, Cagnol, Sébastien, Langlois, Marie-Josée, Boulanger, Jim, Bernatchez, Gérald, Carrier, Julie C., Boudreau, François, Rivard, Nathalie

“…Cathepsin B is a cysteine proteinase that primarily functions as an endopeptidase within endolysosomal compartments in normal cells. However, during tumoral…”
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Loss of interleukin-17 receptor D promotes chronic inflammation-associated tumorigenesis by Girondel, Charlotte, Lévesque, Kim, Langlois, Marie-Josée, Pasquin, Sarah, Saba-El-Leil, Marc K., Rivard, Nathalie, Friesel, Robert, Servant, Marc J., Gauchat, Jean-François, Lesage, Sylvie, Meloche, Sylvain

“…Interleukin-17 receptor D (IL-17RD), also known as similar expression to Fgf genes (SEF), is proposed to act as a signaling hub that negatively regulates…”
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From viruses to cancer: exploring the role of the hepatitis C virus NS3 protein in carcinogenesis by Martineau, Carole-Anne, Rivard, Nathalie, Bisaillon, Martin

“…Hepatitis C virus (HCV) chronically infects approximately 170 million people worldwide and is a known etiological agent of hepatocellular carcinoma (HCC). The…”
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Phosphatases in toll-like receptors signaling: the unfairly-forgotten by Lannoy, Valérie, Côté-Biron, Anthony, Asselin, Claude, Rivard, Nathalie

“…Over the past 2 decades, pattern recognition receptors (PRRs) have been shown to be on the front line of many illnesses such as autoimmune, inflammatory, and…”
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Dual‐specificity phosphatase 6 deletion protects the colonic epithelium against inflammation and promotes both proliferation and tumorigenesis by Beaudry, Katia, Langlois, Marie‐Josée, Montagne, Amélie, Cagnol, Sébastien, Carrier, Julie C., Rivard, Nathalie

“…The Ras/mitogen‐activated protein kinase (MAPK) pathway controls fundamental cellular processes such as proliferation, differentiation, and apoptosis. The…”
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New and Unexpected Biological Functions for the Src-Homology 2 Domain-Containing Phosphatase SHP-2 in the Gastrointestinal Tract by Coulombe, Geneviève, Rivard, Nathalie

“…SHP-2 is a tyrosine phosphatase expressed in most embryonic and adult tissues. SHP-2 regulates many cellular functions including growth, differentiation,…”
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Constitutively active MEK1 is sufficient to induce epithelial‐to‐mesenchymal transition in intestinal epithelial cells and to promote tumor invasion and metastasis by Lemieux, Étienne, Bergeron, Sébastien, Durand, Véronique, Asselin, Claude, Saucier, Caroline, Rivard, Nathalie

“…Constitutive activation of the MAP kinase kinase MEK1 induces oncogenic transformation in intestinal epithelial cells. Loss of cell–cell adhesion followed by…”
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Epithelial Tyrosine Phosphatase SHP-2 Protects against Intestinal Inflammation in Mice by Coulombe, Geneviève, Leblanc, Caroline, Cagnol, Sébastien, Maloum, Faiza, Lemieux, Étienne, Perreault, Nathalie, Feng, Gen-Sheng, Boudreau, François, Rivard, Nathalie

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Epithelial Src homology region 2 domain–containing phosphatase‐1 restrains intestinal growth, secretory cell differentiation, and tumorigenesis by Leblanc, Caroline, Langlois, Marie‐Josée, Coulombe, Geneviève, Vaillancourt‐Lavigueur, Vanessa, Jones, Christine, Carrier, Julie C., Boudreau, François, Rivard, Nathalie

“…ABSTRACT Shp‐1 (Src homology region 2 domain‐containing protein tyrosine phosphatase‐1) is a phosphatase that is highly expressed in hematopoietic and…”
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E2F4 expression is required for cell cycle progression of normal intestinal crypt cells and colorectal cancer cells by Garneau, Hugo, Paquin, Marie-Christine, Carrier, Julie C., Rivard, Nathalie

“…The generation of knock‐out mice for E2F4 gene expression has suggested a role for this transcription factor in establishing and/or maintaining the intestinal…”
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Unveiling the Roles of Low-Density Lipoprotein Receptor-Related Protein 6 in Intestinal Homeostasis, Regeneration and Oncogenesis by Raisch, Jennifer, Côté-Biron, Anthony, Langlois, Marie-Josée, Leblanc, Caroline, Rivard, Nathalie

“…Intestinal epithelial self-renewal is tightly regulated by signaling pathways controlling stem cell proliferation, determination and differentiation. In…”
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The PTEN phosphatase controls intestinal epithelial cell polarity and barrier function: role in colorectal cancer progression by Langlois, Marie-Josée, Bergeron, Sébastien, Bernatchez, Gérald, Boudreau, François, Saucier, Caroline, Perreault, Nathalie, Carrier, Julie C, Rivard, Nathalie

“…The PTEN phosphatase acts on phosphatidylinositol 3,4,5-triphosphates resulting from phosphatidylinositol 3-kinase (PI3K) activation. PTEN expression has been…”
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Constitutive activation of the MEK/ERK pathway inhibits intestinal epithelial cell differentiation by Lemieux, Etienne, Boucher, Marie-Josée, Mongrain, Sébastien, Boudreau, François, Asselin, Claude, Rivard, Nathalie

“…The Ras/Raf/MEK/ERK cascade regulates intestinal epithelial cell proliferation. Indeed, while barely detectable in differentiated cells of the villi,…”
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Human Homolog of Disc-large Is Required for Adherens Junction Assembly and Differentiation of Human Intestinal Epithelial Cells by Laprise, Patrick, Viel, Alain, Rivard, Nathalie

“…We and others have shown that phosphatidylinositol 3-kinase (PI3K) is recruited to and activated by E-cadherin engagement. This PI3K activation is essential…”
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The serine protease inhibitor serpinE2 is a novel target of ERK signaling involved in human colorectal tumorigenesis by Bergeron, Sébastien, Lemieux, Etienne, Durand, Véronique, Cagnol, Sébastien, Carrier, Julie C, Lussier, Jacques G, Boucher, Marie-Josée, Rivard, Nathalie

“…Among the most harmful of all genetic abnormalities that appear in colorectal cancer (CRC) development are mutations of KRAS and its downstream effector BRAF…”
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Dual regulatory role for phosphatase and tensin homolog in specification of intestinal endocrine cell subtypes by Roy, Sébastien A B, Langlois, Marie-Josée, Carrier, Julie C, Boudreau, François, Rivard, Nathalie, Perreault, Nathalie

“…AIM：To investigate the impact of phosphatase and tensin homolog（Pten） in the specification of intestinal enteroendocrine subpopulations.METHODS：Using the…”
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Loss of cathepsin L activity promotes claudin-1 overexpression and intestinal neoplasia by Boudreau, François, Lussier, Carine R, Mongrain, Sébastien, Darsigny, Mathieu, Drouin, Julie L, Doyon, Geneviève, Suh, Eun Ran, Beaulieu, Jean-François, Rivard, Nathalie, Perreault, Nathalie

“…Intestinal epithelial integrity and polarity are maintained by cohesive interactions between cells via the formation of tight junctions. Irregularities in…”
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Abrogation of p27 by cDNA Antisense Suppresses Quiescence (G0 State) in Fibroblasts by Rivard, Nathalie, L'Allemain, Gilles, Bartek, Jiri, Pouysségur, Jacques

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