Search Results - "Rivard, G.‐É."

Consequences of intra-articular bleeding in haemophilia: science to clinical practice and beyond by FORSYTH, A. L., RIVARD, G.-É., VALENTINO, L. A., ZOURIKIAN, N., HOFFMAN, M., MONAHAN, P. E., VAN MEEGEREN, M. E. R., FORRIOL, F.

“…Blood in the joint causes a number of physiological and pathological events that eventually lead to haemophilic arthropathy. Animal models show that blood in…”
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A prospective surveillance study of inhibitor development in haemophilia A patients following a population switch to a third‐generation B‐domain‐deleted recombinant factor VIII by Dubé, E., Bonnefoy, A., Merlen, C., Castilloux, J.‐F., Cloutier, S., Demers, C., Sabapathy, C. A., St‐Louis, J., Vezina, C., Warner, M., Rivard, G.‐É.

“…Introduction Following a provincial tender, most subjects with haemophilia A in Quebec switched their treatment to a third‐generation recombinant…”
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Incidence of hypotension and acute hypotensive transfusion reactions following platelet concentrate transfusions by Du Pont-Thibodeau, G., Robitaille, N., Gauvin, F., Thibault, L., Rivard, G.-É., Lacroix, J., Tucci, M.

“…Background and objectives Platelet concentrates (PCs) are associated with transfusion reactions involving hypotension, particularly bradykinin‐mediated acute…”
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Magnetic resonance imaging and joint outcomes in boys with severe hemophilia A treated with tailored primary prophylaxis in Canada by KRAFT, J., BLANCHETTE, V., BABYN, P., FELDMAN, B., CLOUTIER, S., ISRAELS, S., PAI, M., RIVARD, G.‐E., GOMER, S., McLIMONT, M., MOINEDDIN, R., DORIA, A. S.

“…Background/objectives: Tailored primary prophylaxis (TPP) is a reduced‐intensity treatment program for hemophiliacs with the goal of preventing arthropathy…”
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Chitosan–glycerol phosphate/blood implants elicit hyaline cartilage repair integrated with porous subchondral bone in microdrilled rabbit defects by Hoemann, C.D., Ph.D, Sun, J., M.D., M.Sc, McKee, M.D., Ph.D, Chevrier, A., Ph.D, Rossomacha, E., M.D., Ph.D, Rivard, G.-E., M.D, Hurtig, M., D.V.M, Buschmann, M.D., Ph.D

“…Summary Objective We have previously shown that microfractured ovine defects are repaired with more hyaline cartilage when the defect is treated with in situ…”
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A retrospective cohort study of cancer incidence among patients treated with radiosynoviorthesis by INFANTE-RIVARD, C., RIVARD, G.-E., DEROME, F., CUSSON, A., WINIKOFF, R., CHARTRAND, R., GUAY, J.-P.

“…Radiosynoviorthesis (RS) is an intra‐articular injection of a radioactive colloid for the treatment of synovitis administered most often to patients with…”
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The GBA p.Trp378Gly mutation is a probable French‐Canadian founder mutation causing Gaucher disease and synucleinopathies by Ruskey, J.A., Zhou, S., Santiago, R., Franche, L.‐A., Alam, A., Roncière, L., Spiegelman, D., Fon, E.A., Trempe, J.‐F., Kalia, L.V., Postuma, R.B., Dupre, N., Rivard, G.‐E., Assouline, S., Amato, D., Gan‐Or, Z.

“…Biallelic GBA mutations cause Gaucher disease (GD), and heterozygous carriers are at risk for synucleinopathies. No founder GBA mutations in French‐Canadians…”
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Standardization of thromboelastography: a report from the TEG-ROTEM working group by CHITLUR, M., SORENSEN, B., RIVARD, G. E., YOUNG, G., INGERSLEV, J., OTHMAN, M., NUGENT, D., KENET, G., ESCOBAR, M., LUSHER, J.

“…Laboratory evaluation of bleeding disorders has been performed with the standard clotting assays such as the PT and PTT for several decades. Our improved…”
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Solidification mechanisms of chitosan–glycerol phosphate/blood implant for articular cartilage repair by Marchand, C, Rivard, G.-E, Sun, J, Hoemann, C.D

“…Summary Objective Chitosan–glycerol phosphate (chitosan-GP) is a unique polymer solution that is mixed with whole blood and solidified over microfractured or…”
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An 'ice age' concept? The use of ice in the treatment of acute haemarthrosis in haemophilia by Forsyth, A. L., Zourikian, N., Rivard, G.-E., Valentino, L. A.

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An evaluation of the stability of factor VIII inhibitors in plasma and plasma dried on filter paper discs stored at room temperature by Winikoff, R., Boulanger, A., St Louis, J., Lacroix, S., Rivard, G.-É.

“…The transportation of plasma specimens to specialized haemophilia centre laboratories for anti‐factor VIII inhibitor titre determination is often necessary…”
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Evaluation of the profile of thrombin generation during the process of whole blood clotting as assessed by thrombelastography by RIVARD, G. E., BRUMMEL‐ZIEDINS, K. E., MANN, K. G., FAN, L., HOFER, A., COHEN, E.

“…The objective of this study was to evaluate the possibility of linking the tracing of whole blood clotting in a thrombelastograph® (TEG®) hemostasis system…”
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Tailored prophylaxis in severe hemophilia A: interim results from the first 5 years of the Canadian Hemophilia Primary Prophylaxis Study by FELDMAN, B. M., PAI, M., RIVARD, G. E., ISRAELS, S., POON, M.‐C., DEMERS, C., ROBINSON, S., LUKE, K.‐H., WU, J. K. M., GILL, K., LILLICRAP, D., BABYN, P., MCLIMONT, M., BLANCHETTE, V. S.

“…Background: Prophylactic treatment for severe hemophilia A is likely to be more effective than treatment when bleeding occurs, however, prophylaxis is costly…”
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C3, C5, and factor B bind to chitosan without complement activation by Marchand, C., Bachand, J., Périnêt, J., Baraghis, E., Lamarre, M., Rivard, G. E., De Crescenzo, G., Hoemann, C. D.

“…Chitosan is a polycationic and biocompatible polysaccharide composed of glucosamine and N‐acetyl glucosamine that is chemotactic for neutrophils and stimulates…”
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Effects of moderate-intensity physical exercise on pharmacokinetics of factor VIII and von Willebrand factor in young adults with severe haemophilia A: a pilot study by Zourikian, N., Merlen, C., Bonnefoy, A., St-Louis, J., Rivard, G. E.

“…Introduction In persons with severe haemophilia A (pwshA), infused factor VIII (FVIII) half‐life can vary according to such determinants as blood group, von…”
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Intravenous injection of autologous amniotic fluid induces transient thrombocytopenia in a gravid rabbit model of amniotic fluid embolism by Rannou, B., Rivard, G.-E., Gains, M. J., Bédard, C.

“…Background Amniotic fluid embolism (AFE) is a rare but catastrophic complication of pregnancy characterized by severe hypotension, cardiovascular collapse, and…”
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Optimization of storage conditions for diluted working solutions of porcine factor VIII and performance of the Bethesda assay for the determination of antiporcine FVIII inhibitor titres by Winikoff, R., Boulanger, A., Robinson, P., ST-Louis, J., Lacroix, S., Rivard, G.-É.

“…The use of porcine factor VIII (FVIII) (Hyate:C, Ipsen) has proven to be very successful in treating patients with FVIII inhibitors. The best way to predict…”
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Immune tolerance induction in haemophilia A patients with inhibitors by treatment with recombinant factor VIII: a retrospective non-interventional study by Rivard, G. E., Rothschild, C., Toll, T., Achilles, K.

“…Summary Immune tolerance induction (ITI) can overcome inhibitory factor VIII (FVIII) antibodies in haemophilia A patients receiving FVIII replacement therapy…”
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Generic and disease-specific quality of life among youth and young men with Hemophilia in Canada by St-Louis, J, Urajnik, D J, Ménard, F, Cloutier, S, Klaassen, R J, Ritchie, B, Rivard, G E, Warner, M, Blanchette, V, Young, N L

“…This study was undertaken to explore the longitudinal patterns of health-related quality of life (HRQoL) among youth and young adults with Hemophilia A (HA)…”
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Consensus recommendations for use of central venous access devices in haemophilia by Ewenstein, B. M., Valentino, L. A., Journeycake, J. M., Tarantino, M. D., Shapiro, A. D., Blanchette, V. S., Hoots, W. K., Buchanan, G. R., Manco-Johnson, M. J., Rivard, G.-E., Miller, K. L., Geraghty, S., Maahs, J. A., Stuart, R., Dunham, T., Navickis, R. J.

“…Venous access is essential for delivery of haemophilia factor concentrate. Wherever possible, peripheral veins remain the route of choice, and the use of…”
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