Search Results - "Riva, Marco A."

The serotonin-BDNF duo: Developmental implications for the vulnerability to psychopathology by HOMBERG, Judith Regina, MOLTENI, Raffaella, CALABRESE, Francesca, RIVA, Marco A

“…Serotonin (5-HT) and brain-derived neurotrophin factor (BDNF) are known to modulate behavioral responses to stress and to mediate the therapeutic efficacy of…”
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Genome-wide DNA Methylation Changes in a Mouse Model of Infection-Mediated Neurodevelopmental Disorders by Richetto, Juliet, Massart, Renaud, Weber-Stadlbauer, Ulrike, Szyf, Moshe, Riva, Marco A, Meyer, Urs

“…Abstract Background Prenatal exposure to infectious or inflammatory insults increases the risk of neurodevelopmental disorders. Using a well-established mouse…”
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Stress in Puberty Unmasks Latent Neuropathological Consequences of Prenatal Immune Activation in Mice by Giovanoli, Sandra, Engler, Harald, Engler, Andrea, Richetto, Juliet, Voget, Mareike, Willi, Roman, Winter, Christine, Riva, Marco A., Mortensen, Preben B., Schedlowski, Manfred, Meyer, Urs

“…Prenatal infection and exposure to traumatizing experiences during peripuberty have each been associated with increased risk for neuropsychiatric disorders…”
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Prenatal Immune Activation Induces Maturation-Dependent Alterations in the Prefrontal GABAergic Transcriptome by RICHETTO, Juliet, CALABRESE, Francesca, RIVA, Marco A, MEYER, Urs

“…Neuronal dysfunctions in the cortical GABAergic system have been widely documented in neuropsychiatric disorders with prenatal infectious etiologies, including…”
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Brain-derived neurotrophic factor: a bridge between inflammation and neuroplasticity by Calabrese, Francesca, Rossetti, Andrea C, Racagni, Giorgio, Gass, Peter, Riva, Marco A, Molteni, Raffaella

“…Cytokines are key regulatory mediators involved in the host response to immunological challenges, but also play a critical role in the communication between…”
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Neuronal plasticity: A link between stress and mood disorders by Calabrese, Francesca, Molteni, Raffaella, Racagni, Giorgio, Riva, Marco A

“…Summary Although stress represents the major environmental element of susceptibility for mood disorders, the relationship between stress and disease remains to…”
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Role for the kinase SGK1 in stress, depression, and glucocorticoid effects on hippocampal neurogenesis by Anacker, Christoph, Cattaneo, Annamaria, Musaelyan, Ksenia, Zunszain, Patricia A., Horowitz, Mark, Molteni, Raffaella, Luoni, Alessia, Calabrese, Francesca, Tansey, Katherine, Gennarelli, Massimo, Thuret, Sandrine, Price, Jack, Uher, Rudolf, Riva, Marco A., Pariante, Carmine M.

“…Stress and glucocorticoid hormones regulate hippocampal neurogenesis, but the molecular mechanisms mediating these effects are poorly understood. Here we…”
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Glucocorticoid Receptor and FKBP5 Expression Is Altered Following Exposure to Chronic Stress: Modulation by Antidepressant Treatment by GUIDOTTI, Gianluigi, CALABRESE, Francesca, ANACKER, Christoph, RACAGNI, Giorgio, PARIANTE, Carmine M, RIVA, Marco A

“…Major depression is thought to originate from the interaction between susceptibility genes and adverse environmental events, in particular stress. The…”
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Glucocorticoid-Related Molecular Signaling Pathways Regulating Hippocampal Neurogenesis by ANACKER, Christoph, CATTANEO, Annamaria, PRICE, Jack, RIVA, Marco A, GENNARELLI, Massimo, PARIANTE, Carmine M, LUONI, Alessia, MUSAELYAN, Ksenia, ZUNSZAIN, Patricia A, MILANESI, Elena, RYBKA, Joanna, BERRY, Alessandra, CIRULLI, Francesca, THURET, Sandrine

“…Stress and glucocorticoid hormones regulate hippocampal neurogenesis, but the molecular mechanisms underlying their effects are unknown. We, therefore,…”
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Anti-Stress Properties of Atypical Antipsychotics by Sanson, Alice, Riva, Marco A

“…Stress exposure represents a major environmental risk factor for schizophrenia and other psychiatric disorders, as it plays a pivotal role in the etiology as…”
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CREB, neurogenesis and depression by Gass, Peter, Riva, Marco A.

“…The transcription factor CREB has been implicated in signalling pathways relevant for pathogenesis and therapy of depression. CREB is upregulated and activated…”
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Towards Novel Treatments for Schizophrenia: Molecular and Behavioural Signatures of the Psychotropic Agent SEP-363856 by Begni, Veronica, Sanson, Alice, Luoni, Alessia, Sensini, Federica, Grayson, Ben, Munni, Syeda, Neill, Joanna C, Riva, Marco A

“…Schizophrenia is a complex psychopathology whose treatment is still challenging. Given the limitations of existing antipsychotics, there is urgent need for…”
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BDNF Overexpression in the Ventral Hippocampus Promotes Antidepressant- and Anxiolytic-Like Activity in Serotonin Transporter Knockout Rats by Diniz, Danielle M., Calabrese, Francesca, Brivio, Paola, Riva, Marco A., Grandjean, Joanes, Homberg, Judith R.

“…BDNF plays a pivotal role in neuroplasticity events, vulnerability and resilience to stress-related disorders, being decreased in depressive patients and…”
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Lurasidone Exerts Antidepressant Properties in the Chronic Mild Stress Model through the Regulation of Synaptic and Neuroplastic Mechanisms in the Rat Prefrontal Cortex by Luoni, Alessia, Macchi, Flavia, Papp, Mariusz, Molteni, Raffaella, Riva, Marco A.

“…Background: Major depression is associated with several alterations, including reduced neuronal plasticity and impaired synaptic function, which represent an…”
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Prenatal maternal factors in the development of cognitive impairments in the offspring by Richetto, Juliet, Riva, Marco A

“…Abstract Different environmental factors acting during sensitive prenatal periods can have a negative impact on neurodevelopment and predispose the individual…”
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Gene-environment interaction in major depression: focus on experience-dependent biological systems by Lopizzo, Nicola, Bocchio Chiavetto, Luisella, Cattane, Nadia, Plazzotta, Giona, Tarazi, Frank I, Pariante, Carmine M, Riva, Marco A, Cattaneo, Annamaria

“…Major depressive disorder (MDD) is a multifactorial and polygenic disorder, where multiple and partially overlapping sets of susceptibility genes interact each…”
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Definition, assessment and treatment of cognitive impairment associated with schizophrenia: expert opinion and practical recommendations by Vita, Antonio, Barlati, Stefano, Cavallaro, Roberto, Mucci, Armida, Riva, Marco A, Rocca, Paola, Rossi, Alessandro, Galderisi, Silvana

“…A considerable proportion of patients with schizophrenia perform below population norms on standardized neuropsychological tests, and the performance of those…”
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Involvement of the IL-6 Signaling Pathway in the Anti-Anhedonic Effect of the Antidepressant Agomelatine in the Chronic Mild Stress Model of Depression by Rossetti, Andrea C., Paladini, Maria Serena, Brüning, Cesar Augusto, Spero, Vittoria, Cattaneo, Maria Grazia, Racagni, Giorgio, Papp, Mariusz, Riva, Marco A., Molteni, Raffaella

“…Neuroinflammation has emerged as an important factor in the molecular underpinnings of major depressive disorder (MDD) pathophysiology and in the mechanism of…”
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Bdnf-Nrf-2 crosstalk and emotional behavior are disrupted in a sex-dependent fashion in adolescent mice exposed to maternal stress or maternal obesity by Musillo, Chiara, Creutzberg, Kerstin C., Collacchi, Barbara, Ajmone-Cat, Maria Antonietta, De Simone, Roberta, Lepre, Marcello, Amrein, Irmgard, Riva, Marco A., Berry, Alessandra, Cirulli, Francesca

“…Maternal obesity has been recognized as a stressor affecting the developing fetal brain, leading to long-term negative outcomes comparable to those resulting…”
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Schizophrenia and "unmet needs": From diagnosis to care in Italy by Galderisi, Silvana, Riva, Marco A, Girardi, Paolo, Amore, Mario, Carpiniello, Bernardo, Aguglia, Eugenio, Fagiolini, Andrea, Mucci, Armida, Vita, Antonio

“…Schizophrenia is a leading cause of disability. People living with schizophrenia (PLWS) present unemployment, social isolation, excess mortality and morbidity,…”
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