Search Results - "Riul, Thalita B."
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1
Galectin-1 induces reversible phosphatidylserine exposure at the plasma membrane
Published in Molecular biology of the cell (01-03-2009)“…Cells normally undergo physiological turnover through the induction of apoptosis and phagocytic removal, partly through exposure of cell surface…”
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2
Leishmanicidal evaluation of tetrahydroprotoberberine and spirocyclic erythrina-alkaloids
Published in Molecules (Basel, Switzerland) (05-05-2014)“…Leishmaniasis is one of the World's most problematic diseases in developing countries. Traditional medicines to treat leishmaniasis have serious side effects,…”
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3
Binding of triazole-linked galactosyl arylsulfonamides to galectin-3 affects Trypanosoma cruzi cell invasion
Published in Bioorganic & medicinal chemistry (01-11-2017)“…[Display omitted] The synthesis of the O-3 triazole-linked galactosyl arylsulfonamides 1–7 as potential inhibitors of Trypanosoma cruzi cell invasion is…”
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4
A Synthetic MUC1 Glycopeptide Bearing [beta]GalNAc-Thr as a Tn Antigen Isomer Induces the Production of Antibodies against Tumor Cells
Published in Chembiochem : a European journal of chemical biology (16-03-2017)“…This study presents the synthesis of the novel protected O-glycosylated amino acid derivatives 1 and 2, containing [beta]GalNAc-SerOBn and [beta]GalNAc-ThrOBn…”
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5
Antibodies against Mucin-Based Glycopeptides Affect Trypanosoma cruzi Cell Invasion and Tumor Cell Viability
Published in Chembiochem : a European journal of chemical biology (07-07-2014)“…This study describes the synthesis of glycopeptides NHAc[βGal]‐(Thr)2‐[αGalNAc]‐(Thr)2‐[αGlcNAc]‐(Thr)2Gly‐OVA (1‐OVA) and…”
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6
Antithrombotic activity of Batroxase, a metalloprotease from Bothrops atrox venom, in a model of venous thrombosis
Published in International journal of biological macromolecules (01-02-2017)“…Snake venoms are great sources of bioactive molecules, which may be used as models for new drugs. Toxins that interfere in hemostasis have received…”
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7
A Synthetic MUC1 Glycopeptide Bearing βGalNAc‐Thr as a Tn Antigen Isomer Induces the Production of Antibodies against Tumor Cells
Published in Chembiochem : a European journal of chemical biology (16-03-2017)“…This study presents the synthesis of the novel protected O‐glycosylated amino acid derivatives 1 and 2, containing βGalNAc‐SerOBn and βGalNAc‐ThrOBn units,…”
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8
Proteomic and functional analysis identifies galectin-1 as a novel regulatory component of the cytotoxic granule machinery
Published in Cell death & disease (07-12-2017)“…Secretory granules released by cytotoxic T lymphocytes (CTLs) are powerful weapons against intracellular microbes and tumor cells. Despite significant…”
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9
Galatrox is a C-type lectin in Bothrops atrox snake venom that selectively binds LacNAc-terminated glycans and can induce acute inflammation
Published in Glycobiology (Oxford) (01-11-2014)“…Previous studies indicate that snake venom contains glycan-binding proteins (GBPs), although the binding specificity and biological activities of many of these…”
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10
rBaltMIP, a recombinant alpha-type myotoxin inhibitor from Bothrops alternatus (Rhinocerophis alternatus) snake, as a potential candidate to complement the antivenom therapy
Published in Toxicon (Oxford) (15-12-2016)“…Phospholipase A2 inhibitors (PLIs) are important targets in the search and development of new drugs. This study aimed at evaluating the potential of an…”
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11
In vitro Metabolism and Cytotoxicity of Parthenolide: The Complete Identification of the Major Oxidative Product and the Evaluation of Trypanocidal and Leishmanicidal Activities
Published in Journal of the Brazilian Chemical Society (2025)“…Parthenolide (PTN) is a secondary metabolite of the plant Tanacetum parthenium (L.) Schulz Bip. and is considered the chemical marker of this species. This…”
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12
Application of the Negishi Reaction in the Synthesis of Thiophene-Based Lignans Analogues with Leishmanicidal Effects
Published in Journal of the Brazilian Chemical Society (01-10-2014)“…Lignans represent a well-known group of natural products with anti-protozoal activity. In the literature there are many examples of the anti-parasitic activity…”
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