Search Results - "Ritter, Tobias"

A Perspective on Late-Stage Aromatic C–H Bond Functionalization by Zhang, Li, Ritter, Tobias

“…Late-stage functionalization of C–H bonds (C–H LSF) can provide a straightforward approach to the efficient synthesis of functionalized complex molecules…”
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Site-Selective C–H alkylation of Complex Arenes by a Two-Step Aryl Thianthrenation-Reductive Alkylation Sequence by Lansbergen, Beatrice, Granatino, Paola, Ritter, Tobias

“…Herein, we present an undirected para-selective two-step C–H alkylation of complex arenes useful for late-stage functionalization. The combination of a…”
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Introduction of Fluorine and Fluorine-Containing Functional Groups by Liang, Theresa, Neumann, Constanze N., Ritter, Tobias

“…Over the past decade, the most significant, conceptual advances in the field of fluorination were enabled most prominently by organo‐ and transition‐metal…”
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Radical Decarboxylative Carbometalation of Benzoic Acids: A Solution to Aromatic Decarboxylative Fluorination by Xu, Peng, López-Rojas, Priscila, Ritter, Tobias

“…Abundant aromatic carboxylic acids exist in great structural diversity from nature and synthesis. To date, the synthetically valuable decarboxylative…”
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Synthesis of Benzylic Alcohols by C–H Oxidation by Tanwar, Lalita, Börgel, Jonas, Ritter, Tobias

“…Selective methylene C–H oxidation for the synthesis of alcohols with a broad scope and functional group tolerance is challenging due to the high proclivity for…”
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Catalysis for fluorination and trifluoromethylation by Furuya, Takeru, Kamlet, Adam S., Ritter, Tobias

“…Fluorination to the fore When incorporated into organic compounds, fluorine atoms often impart useful properties. For example, fluorination improves the…”
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Vinyl Thianthrenium Tetrafluoroborate: A Practical and Versatile Vinylating Reagent Made from Ethylene by Juliá, Fabio, Yan, Jiyao, Paulus, Fritz, Ritter, Tobias

“…The use of vinyl electrophiles in synthesis has been hampered by the lack of access to a suitable reagent that is practical and of appropriate reactivity. In…”
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Site-selective and versatile aromatic C−H functionalization by thianthrenation by Berger, Florian, Plutschack, Matthew B., Riegger, Julian, Yu, Wanwan, Speicher, Samira, Ho, Matthew, Frank, Nils, Ritter, Tobias

“…Direct C–H functionalization can quickly increase useful structural and functional molecular complexity 1 – 3 . Site selectivity can sometimes be achieved…”
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Facile C–F Bond Formation through a Concerted Nucleophilic Aromatic Substitution Mediated by the PhenoFluor Reagent by Neumann, Constanze N, Ritter, Tobias

“…Conspectus Late-stage fluorination reactions aim to reduce the synthetic limitations of conventional organofluorine chemistry with respect to substrate scope…”
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Fluorination of Boronic Acids Mediated by Silver(I) Triflate by Furuya, Takeru, Ritter, Tobias

“…A regiospecific Ag-mediated fluorination reaction of aryl- and alkenylboronic acids and esters is reported. The fluorination reaction uses commercially…”
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Aryl Sulfonium Salts for Site‐Selective Late‐Stage Trifluoromethylation by Ye, Fei, Berger, Florian, Jia, Hao, Ford, Joseph, Wortman, Alan, Börgel, Jonas, Genicot, Christophe, Ritter, Tobias

“…Incorporation of the CF3 group into arenes has found increasing importance in drug discovery. Herein, we report the first photoredox‐catalyzed cross‐coupling…”
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Site‐Selective C−H Oxygenation via Aryl Sulfonium Salts by Sang, Ruocheng, Korkis, Stamatis E., Su, Wanqi, Ye, Fei, Engl, Pascal S., Berger, Florian, Ritter, Tobias

“…Herein, we report a two‐step process forming arene C−O bonds in excellent site‐selectivity at a late‐stage. The C−O bond formation is achieved by selective…”
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PhenoFluorMix: Practical Chemoselective Deoxyfluorination of Phenols by Fujimoto, Teppei, Ritter, Tobias

“…A practical deoxyfluorination with novel deoxyfluorinating reagent PhenoFluorMix, a mixture of N,N′-1,3-bis(2,6-diisopropylphenyl)chloroimidazolium chloride…”
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Regio‐ and Stereoselective Thianthrenation of Olefins To Access Versatile Alkenyl Electrophiles by Chen, Junting, Li, Jiakun, Plutschack, Matthew B., Berger, Florian, Ritter, Tobias

“…Herein, we report a regioselective alkenyl electrophile synthesis from unactivated olefins that is based on a direct and regioselective C−H thianthrenation…”
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Late-Stage Fluorination: From Fundamentals to Application by Campbell, Michael G, Ritter, Tobias

“…In this brief account, we review work from our lab with a focus on late-stage introduction of fluorine and fluorinated functional groups into small molecules…”
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Aromatic C-H amination in hexafluoroisopropanol by D'Amato, Erica M, Börgel, Jonas, Ritter, Tobias

“…We report a direct radical aromatic amination reaction that provides unprotected anilines with an improvement in the substrate scope compared to prior art…”
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Divergent Late‐Stage (Hetero)aryl C−H Amination by the Pyridinium Radical Cation by Ham, Won Seok, Hillenbrand, Julius, Jacq, Jérôme, Genicot, Christophe, Ritter, Tobias

“…(Hetero)arylamines constitute some of the most prevalent functional molecules, especially as pharmaceuticals. However, structurally complex aromatics currently…”
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Carbon–Fluorine Reductive Elimination from Nickel(III) Complexes by Lee, Heejun, Börgel, Jonas, Ritter, Tobias

“…We report a C−F reductive elimination from a characterized first‐row aryl metal fluoride complex. Reductive elimination from the presented nickel(III)…”
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Site‐Selective Late‐Stage Aromatic [18F]Fluorination via Aryl Sulfonium Salts by Xu, Peng, Zhao, Da, Berger, Florian, Hamad, Aboubakr, Rickmeier, Jens, Petzold, Roland, Kondratiuk, Mykhailo, Bohdan, Kostiantyn, Ritter, Tobias

“…Site‐selective functionalization of C−H bonds in small complex molecules is a long‐standing challenge in organic chemistry. Herein, we report a broadly…”
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C–N Cross-Couplings for Site-Selective Late-Stage Diversification via Aryl Sulfonium Salts by Engl, Pascal S, Häring, Andreas P, Berger, Florian, Berger, Georg, Pérez-Bitrián, Alberto, Ritter, Tobias

“…We report diverse C–N cross-coupling reactions of aryl thianthrenium salts that are formed site-selectively by direct C–H functionalization. The scope of…”
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