Search Results - "Ritter, David M"

Prevalence of thoracoabdominal imaging findings in tuberous sclerosis complex by Ritter, David M, Fessler, Bailey K, Ebrahimi-Fakhari, Daniel, Wei, Jun, Franz, David N, Krueger, Darcy A, Trout, Andrew T, Towbin, Alexander J

“…Tuberous sclerosis complex (TSC) results in neurodevelopmental phenotypes, benign tumors, and cysts throughout the body. Recent studies show numerous rare…”
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A-Type KV Channels in Dorsal Root Ganglion Neurons: Diversity, Function, and Dysfunction by Zemel, Benjamin M., Ritter, David M., Covarrubias, Manuel, Muqeem, Tanziyah

“…A-type voltage-gated potassium (Kv) channels are major regulators of neuronal excitability that have been mainly characterized in the central nervous system…”
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Modeling-independent elucidation of inactivation pathways in recombinant and native A-type Kv channels by Fineberg, Jeffrey D, Ritter, David M, Covarrubias, Manuel

“…A-type voltage-gated K(+) (Kv) channels self-regulate their activity by inactivating directly from the open state (open-state inactivation [OSI]) or by…”
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Exploring the neurological features of individuals with germline PTEN variants: A multicenter study by Dhawan, Andrew, Baitamouni, Sarah, Liu, Darren, Busch, Robyn, Klaas, Patricia, Frazier, Thomas W, Srivastava, Siddharth, Parikh, Sumit, Hsich, Gary E, Friedman, Neil R, Ritter, David M, Hardan, Antonio Y, Martinez-Agosto, Julian A, Sahin, Mustafa, Eng, Charis

“…PTEN, a known tumor suppressor gene, is a mediator of neurodevelopment. Individuals with germline pathogenic variants in the PTEN gene, molecularly defined as…”
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Treatment of SCN4A‐induced myotonic crisis by Ritter, David M., Tian, Cuixia, Broomall, Eileen

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A-Type K V Channels in Dorsal Root Ganglion Neurons: Diversity, Function, and Dysfunction by Zemel, Benjamin M, Ritter, David M, Covarrubias, Manuel, Muqeem, Tanziyah

“…A-type voltage-gated potassium (Kv) channels are major regulators of neuronal excitability that have been mainly characterized in the central nervous system…”
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Mammalian Target of Rapamycin Inhibitor Levels Decrease Under Cenobamate Treatment by Becker, Lena-Luise, Agricola, Karen, Ritter, David M., Krueger, Darcy A., Franz, David Neal

“…Everolimus therapy has been approved in Tuberous Sclerosis Complex (TSC), for drug-resistant epilepsy as adjunctive therapy. A novel anti-seizure medication is…”
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Impact of Race in Missed Appointments in Pediatric Neurology Resident Clinic at a Large Tertiary Medical Center by Albor, Lauren C., Horn, Paul S., Venkatesan, Charu, Ritter, David M.

“…Missed medical appointments are a common problem across specialties. The discontinuity of care leads to unplanned health care utilization, increased costs, and…”
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In Silico Predictions of KCNQ Variant Pathogenicity in Epilepsy by Ritter, David M., Horn, Paul S., Holland, Katherine D.

“…Variants in KCNQ2 and KCNQ3 may cause benign neonatal familial seizures and early infantile epileptic encephalopathy. Previous reports suggest that in silico…”
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Dysregulation of Kv3.4 channels in dorsal root ganglia following spinal cord injury by Ritter, David M, Zemel, Benjamin M, Hala, Tamara J, O'Leary, Michael E, Lepore, Angelo C, Covarrubias, Manuel

“…Spinal cord injury (SCI) patients develop chronic pain involving poorly understood central and peripheral mechanisms. Because dysregulation of the…”
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Diabetes in Individuals With Tuberous Sclerosis Complex Treated With mTOR Inhibitors by Agricola, Karen, Stires, Gabrielle, Krueger, Darcy A., Capal, Jamie K., Franz, David N., Ritter, David M.

“…Tuberous sclerosis complex (TSC) is a genetic disorder that is manifested in multiple body systems. A mammalian target of rapamycin (mTOR) inhibitor (mTORi),…”
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Modulation of Kv3.4 channel N‐type inactivation by protein kinase C shapes the action potential in dorsal root ganglion neurons by Ritter, David M., Ho, Cojen, O’Leary, Michael E., Covarrubias, Manuel

“…Non‐technical summary  The orchestrated activity of an ensemble of voltage‐gated ion channels determines the initiation, shape and duration of the action…”
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Acute Ataxia and Paresthesia in a Healthy 5-year-old Girl by Taylor, Richard J., Ritter, David M., Frazier, Maria E., Zackoff, Matthew W.

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Estradiol- and Progesterone-Associated Changes in microRNA-Induced Silencing and Reduced Antiseizure Efficacy of an Antagomir in Female Mice by Tiwari, Durgesh, Rajathi, Valerine, Rymer, Jeffrey K, Beasley, Lindsay N, McGann, Amanda M, Bunk, Alexander T, Parkins, Emma V, Rice, McKenzie F, Smith, Katie E, Ritter, David M, White, Angela R, Doerning, Carolyn M, Gross, Christina

“…About one-third of individuals living with epilepsy have treatment-resistant seizures. Alternative therapeutic strategies are thus urgently needed. One…”
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Preventative treatment of tuberous sclerosis complex with sirolimus: Phase I safety and efficacy results by Capal, Jamie K., Ritter, David M., Franz, David Neal, Griffith, Molly, Currans, Kristn, Kent, Bridget, Martina Bebin, E., Northrup, Hope, Koenig, Mary Kay, Mizuno, Tomoyuki, Vinks, Alexander A., Galandi, Stephanie L., Zhang, Wujuan, Setchell, Kenneth D.R., Kremer, Kelly M., Prada, Carlos M., Greiner, Hansel M., Holland‐Bouley, Katherine, Horn, Paul S., Krueger, Darcy A.

“…Abstract Objective Tuberous sclerosis complex (TSC) results from overactivity of the mechanistic target of rapamycin (mTOR). Sirolimus and everolimus are mTOR…”
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Kv3.4 channel function and dysfunction in nociceptors by Ritter, David M, Zemel, Benjamin M, Lepore, Angelo C, Covarrubias, Manuel

“…Recently, we reported the isolation of the Kv3.4 current in dorsal root ganglion (DRG) neurons and described dysregulation of this current in a spinal cord…”
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Kv3.4 channel function and modulation in nociceptors: Novel insights into the pathophysiology of neuropathic pain by Ritter, David M

“…Chronic neuropathic pain affects millions of people worldwide; however, there remain few effective treatments for this condition. This is especially true in…”
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Reducing properties of potassium silyl by Williams, Victor A, Ritter, David M

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Electron-diffraction investigations of the molecular structures of cis- and trans-1,2-dimethyldiborane by Hedberg, Lise, Hedberg, Kenneth, Kohler, David A., Ritter, David M., Schomaker, Verner

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Treatment of SCN4A-induced myotonic crisis by Ritter, David M, Tian, Cuixia, Broomall, Eileen

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