Search Results - "Ritola, Kimberly D."
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Parallel, Redundant Circuit Organization for Homeostatic Control of Feeding Behavior
Published in Cell (05-12-2013)“…Neural circuits for essential natural behaviors are shaped by selective pressure to coordinate reliable execution of flexible goal-directed actions. However,…”
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A Designer AAV Variant Permits Efficient Retrograde Access to Projection Neurons
Published in Neuron (Cambridge, Mass.) (19-10-2016)“…Efficient retrograde access to projection neurons for the delivery of sensors and effectors constitutes an important and enabling capability for neural circuit…”
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3
A Brainstem-Spinal Cord Inhibitory Circuit for Mechanical Pain Modulation by GABA and Enkephalins
Published in Neuron (Cambridge, Mass.) (22-02-2017)“…Pain thresholds are, in part, set as a function of emotional and internal states by descending modulation of nociceptive transmission in the spinal cord…”
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Molecular characterization of projection neuron subtypes in the mouse olfactory bulb
Published in eLife (22-07-2021)“…Projection neurons (PNs) in the mammalian olfactory bulb (OB) receive input from the nose and project to diverse cortical and subcortical areas. Morphological…”
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Rescue of behavioral and electrophysiological phenotypes in a Pitt-Hopkins syndrome mouse model by genetic restoration of Tcf4 expression
Published in eLife (10-05-2022)“…Pitt-Hopkins syndrome (PTHS) is a neurodevelopmental disorder caused by monoallelic mutation or deletion in the ( ) gene. Individuals with PTHS typically…”
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Dual-isoform hUBE3A gene transfer improves behavioral and seizure outcomes in Angelman syndrome model mice
Published in JCI insight (22-10-2021)“…Loss of the maternal UBE3A allele causes Angelman syndrome (AS), a debilitating neurodevelopmental disorder. Here, we devised an AS treatment strategy based on…”
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The organization and development of cortical interneuron presynaptic circuits are area specific
Published in Cell reports (Cambridge) (09-11-2021)“…Parvalbumin and somatostatin inhibitory interneurons gate information flow in discrete cortical areas that compute sensory and cognitive functions. Despite the…”
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Cell culture–produced hepatitis C virus does not infect peripheral blood mononuclear cells
Published in Hepatology (Baltimore, Md.) (01-12-2008)“…Hepatitis C virus (HCV) replicates primarily in the liver, but HCV RNA has been observed in association with other tissues and cells including B and T…”
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Single-capsid identification of full and empty status of recombinant adeno-associated viruses via resistive pulse sensing
Published in Sensors and actuators reports (01-12-2024)“…•Fabrication in a plastic using nano-injection molding a sensor with mixed-scale structures (nm → mm) with successful enclosure of the fluidic network via…”
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Vav2 Is an Activator of Cdc42, Rac1, and RhoA
Published in The Journal of biological chemistry (07-04-2000)“…Vav and Vav2 are members of the Dbl family of proteins that act as guanine nucleotide exchange factors (GEFs) for Rho family proteins. Whereas Vav expression…”
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Clonal B cells in patients with hepatitis C virus–associated mixed cryoglobulinemia contain an expanded anergic CD21low B-cell subset
Published in Blood (19-05-2011)“…Hepatitis C virus (HCV) is associated with the B-cell lymphoproliferative disorders mixed cryoglobulinemia (MC) and non-Hodgkin lymphoma. We have previously…”
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