Search Results - "Ritchey, E"

Genome-Wide Analysis of RNA Secondary Structure by Bevilacqua, Philip C, Ritchey, Laura E, Su, Zhao, Assmann, Sarah M

“…Single-stranded RNA molecules fold into extraordinarily complicated secondary and tertiary structures as a result of intramolecular base pairing. In vivo,…”
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NusG-dependent RNA polymerase pausing is a common feature of riboswitch regulatory mechanisms by Jayasinghe, Oshadhi T, Ritchey, Laura E, Breil, Thomas, Newman, Paxton, Yakhnin, Helen, Babitzke, Paul

“…Abstract Transcription by RNA polymerase is punctuated by transient pausing events. Pausing provides time for RNA folding and binding of regulatory factors to…”
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mRNA structural elements immediately upstream of the start codon dictate dependence upon eIF4A helicase activity by Waldron, Joseph A, Tack, David C, Ritchey, Laura E, Gillen, Sarah L, Wilczynska, Ania, Turro, Ernest, Bevilacqua, Philip C, Assmann, Sarah M, Bushell, Martin, Le Quesne, John

“…The RNA helicase eIF4A1 is a key component of the translation initiation machinery and is required for the translation of many pro-oncogenic mRNAs. There is…”
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Prognostic factors of brain metastasis and survival among HER2-positive metastatic breast cancer patients: a systematic literature review by Hackshaw, Michelle D., Danysh, Heather E., Henderson, Mackenzie, Wang, Eric, Tu, Nora, Islam, Zahidul, Ladner, Amy, Ritchey, Mary E., Salas, Maribel

“…Abstract Background Patients with breast cancer who overexpress the human epidermal growth factor receptor 2 (HER2) and subsequently develop brain metastasis…”
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Increased risk of falls and fractures in patients with psychosis and Parkinson disease by Forns, Joan, Layton, J Bradley, Bartsch, Jennifer, Turner, Mary Ellen, Dempsey, Colleen, Anthony, Mary, Ritchey, Mary E, Demos, George

“…Evaluate whether the risk of falls and fractures differs between patients with Parkinson disease with psychosis (PDP) and patients with Parkinson disease (PD)…”
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Risks of Uterine Perforation and Expulsion Associated With Intrauterine Devices by Fassett, Michael J, Reed, Susan D, Rothman, Kenneth J, Pisa, Federica, Schoendorf, Juliane, Wahdan, Yesmean, Peipert, Jeffrey F, Gatz, Jennifer, Ritchey, Mary E, Armstrong, Mary Anne, Raine-Bennett, Tina, Postlethwaite, Debbie, Getahun, Darios, Shi, Jiaxiao M, Xie, Fagen, Chiu, Vicki Y, Im, Theresa M, Takhar, Harpreet S, Wang, Jinyi, Anthony, Mary S

“…The APEX-IUD (Association of Perforation and Expulsion of Intrauterine Devices) study evaluated the association of postpartum timing of intrauterine device…”
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Effect of turning frequency and season on composting materials from swine high-rise facilities by Cook, K.L., Ritchey, E.L., Loughrin, J.H., Haley, M., Sistani, K.R., Bolster, C.H.

“…•High-rise swine facilities permit liquid slurries to be converted to compostable solids.•Swine high-rise materials compost well in windrows despite low…”
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Intravenous Immunoglobulin Treatment Patterns and Outcomes in Patients with Chronic Inflammatory Demyelinating Polyradiculoneuropathy: A US Claims Database Analysis by Anderson-Smits, Colin, Ritchey, Mary E., Huang, Zhongwen, Chavan, Shailesh, Souayah, Nizar, Ay, Hakan, Layton, J. Bradley

“…Introduction Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a rare progressive or relapsing inflammatory disease. Intravenous…”
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Intravenous Immunoglobulin Initiation in Patients with Chronic Inflammatory Demyelinating Polyradiculoneuropathy: A US Claims-based Cohort Study by Layton, J. Bradley, Ritchey, Mary E., Huang, Zhongwen, Chavan, Shailesh, Ay, Hakan, Souayah, Nizar, Anderson-Smits, Colin

“…Introduction Intravenous immunoglobulin (IVIG) is recommended as first-line therapy for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), an…”
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Assessment of Codispensing Patterns of Mirabegron and Prespecified CYP2D6 Substrates in Patients with Overactive Bladder by Wang, Jingjun, Ritchey, Mary E., Reynolds, Kamika, Carbonneau, Madeleine, Carrera, Adam, Goti, Noelia, Horn, John R., Girman, Cynthia J.

“…Background Patients with overactive bladder (OAB) experience sudden, intense urges to urinate, which may include urge urinary incontinence and nocturia…”
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CYP2D6 Substrate Dispensing Among Patients Dispensed Mirabegron: An Administrative Claims Analysis by Ritchey, Mary E., Wang, Jingjun, Young, Jessica C., Chandra, Rajat, Carrera, Adam, Goti, Noelia, Horn, John R., Girman, Cynthia J.

“…Background Overactive bladder (OAB) is characterized by the presence of bothersome urinary symptoms. Pharmacologic treatment options for OAB include…”
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Data sources and applied methods for paclitaxel safety signal discernment by Gressler, Laura Elisabeth, Avila-Tang, Erika, Mao, Jialin, Avalos-Pacheco, Alejandra, Shaya, Fadia T, Torosyan, Yelizaveta, Liebeskind, Alexander, Kinard, Madris, Mack, Christina D, Normand, Sharon-Lise, Ritchey, Mary E, Marinac-Dabic, Danica

“…Following the identification of a late mortality signal, the Food and Drug Administration (FDA) convened an advisory panel that concluded that additional…”
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Use of Contrave, Naltrexone with Bupropion, Bupropion, or Naltrexone and Major Adverse Cardiovascular Events: A Systematic Literature Review by Dahlberg, Sarah, Chang, Ellen T, Weiss, Sheila R, Dopart, Pamela, Gould, Errol, Ritchey, Mary E

“…Naltrexone/Bupropion extended release (ER; Contrave) is an extended-release, fixed-dose combination medication of naltrexone (8 mg) and bupropion (90 mg) for…”
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The pattern of expression of guanine nucleotide-binding protein β3 in the retina is conserved across vertebrate species by Ritchey, E.R, Bongini, R.E, Code, K.A, Zelinka, C, Petersen-Jones, S, Fischer, A.J

“…Abstract Guanine nucleotide-binding protein β3 (GNB3) is an isoform of the β subunit of the heterotrimeric G protein second messenger complex that is commonly…”
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From Clinical Phenotype to Genotypic Modelling: Incidence and Prevalence of Recessive Dystrophic Epidermolysis Bullosa (RDEB) by Eichstadt, Shaundra, Tang, Jean Y, Solis, Daniel C, Siprashvili, Zurab, Marinkovich, M Peter, Whitehead, Nedra, Schu, Matthew, Fang, Fang, Erickson, Stephen W, Ritchey, Mary E, Colao, Max, Spratt, Kaye, Shaygan, Amir, Ahn, Mark J, Sarin, Kavita Y

“…Recessive dystrophic epidermolysis bullosa (RDEB) is an inherited genetic disorder characterized by recurrent and chronic open wounds with significant…”
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Structure-seq2: sensitive and accurate genome-wide profiling of RNA structure in vivo by Ritchey, Laura E, Su, Zhao, Tang, Yin, Tack, David C, Assmann, Sarah M, Bevilacqua, Philip C

“…RNA serves many functions in biology such as splicing, temperature sensing, and innate immunity. These functions are often determined by the structure of RNA…”
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Genome-wide RNA structurome reprogramming by acute heat shock globally regulates mRNA abundance by Su, Zhao, Tang, Yin, Ritchey, Laura E., Tack, David C., Zhu, Mengmeng, Bevilacqua, Philip C., Assmann, Sarah M.

“…The heat shock response is crucial for organism survival in natural environments. RNA structure is known to influence numerous processes related to gene…”
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Can Weight of Evidence, Quantitative Bias, and Bounding Methods Evaluate Robustness of Real-world Evidence for Regulator and Health Technology Assessment Decisions on Medical Interventions? by Rosen, Emma M, Ritchey, Mary E, Girman, Cynthia J

“…High-quality evidence is crucial for health care intervention decision-making. These decisions frequently use nonrandomized data, which can be more vulnerable…”
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Identification and validation of uterine perforation, intrauterine device expulsion, and breastfeeding in four health care systems with electronic health records by Anthony, Mary S, Armstrong, Mary Anne, Getahun, Darios, Scholes, Delia, Gatz, Jennifer, Schulze-Rath, Renate, Postlethwaite, Debbie, Merchant, Maqdooda, Alabaster, Amy L, Chillemi, Giulia, Raine-Bennett, Tina, Xie, Fagen, Chiu, Vicki Y, Im, Theresa M, Takhar, Harpreet S, Fassett, Michael, Grafton, Jane, Cronkite, David, Ichikawa, Laura, Reed, Susan D, Hui, Siu Lui, Ritchey, Mary E, Saltus, Catherine W, Andrews, Elizabeth B, Rothman, Kenneth J, Asiimwe, Alex, Lynen, Richard, Schoendorf, Juliane

“…To validate algorithms identifying uterine perforations and intrauterine device (IUD) expulsions and to ascertain availability of breastfeeding status at the…”
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Incidence of pneumonitis/interstitial lung disease induced by HER2-targeting therapy for HER2-positive metastatic breast cancer by Hackshaw, Michelle D., Danysh, Heather E., Singh, Jasmeet, Ritchey, Mary E., Ladner, Amy, Taitt, Corina, Camidge, D. Ross, Iwata, Hiroji, Powell, Charles A.

“…Purpose Anti-human epidermal growth factor receptor 2 (HER2) therapies are associated with interstitial lung disease (ILD), also referred to as pneumonitis. In…”
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