Search Results - "Rita Emma, Maria"

Potential Uses of Olive Oil Secoiridoids for the Prevention and Treatment of Cancer: A Narrative Review of Preclinical Studies by Emma, Maria Rita, Augello, Giuseppa, Di Stefano, Vita, Azzolina, Antonina, Giannitrapani, Lydia, Montalto, Giuseppe, Cervello, Melchiorre, Cusimano, Antonella

“…The Mediterranean diet (MD) is a combination of foods mainly rich in antioxidants and anti-inflammatory nutrients that have been shown to have many…”
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Biocompatible Lipid Nanoparticles as Carriers To Improve Curcumin Efficacy in Ovarian Cancer Treatment by Bondì, Maria Luisa, Emma, Maria Rita, Botto, Chiara, Augello, Giuseppa, Azzolina, Antonina, Di Gaudio, Francesca, Craparo, Emanuela Fabiola, Cavallaro, Gennara, Bachvarov, Dimcho, Cervello, Melchiorre

“…Curcumin is a natural molecule with proved anticancer efficacy on several human cancer cell lines. However, its clinical application has been limited due to…”
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NUPR1 protects liver from lipotoxic injury by improving the endoplasmic reticulum stress response by Teresa Borrello, Maria, Rita Emma, Maria, Listi, Angela, Rubis, Marion, Coslet, Sergiu, Augello, Giuseppa, Cusimano, Antonella, Cabibi, Daniela, Porcasi, Rossana, Giannitrapani, Lydia, Soresi, Maurizio, Pantuso, Gianni, Blyth, Karen, Montalto, Giuseppe, Pin, Christopher, Cervello, Melchiorre, Iovanna, Juan

“…Non‐alcoholic fatty liver (NAFL) and related syndromes affect one‐third of the adult population in industrialized and developing countries. Lifestyle and…”
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Pivotal roles of glycogen synthase-3 in hepatocellular carcinoma by Cervello, Melchiorre, Augello, Giuseppa, Cusimano, Antonella, Emma, Maria Rita, Balasus, Daniele, Azzolina, Antonina, McCubrey, James A., Montalto, Giuseppe

“…Hepatocellular carcinoma (HCC) is one of the most common cancers in the world, and represents the second most frequently cancer and third most common cause of…”
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Effects of the Mutant TP53 Reactivator APR-246 on Therapeutic Sensitivity of Pancreatic Cancer Cells in the Presence and Absence of WT-TP53 by Abrams, Stephen L, Duda, Przemysław, Akula, Shaw M, Steelman, Linda S, Follo, Matilde L, Cocco, Lucio, Ratti, Stefano, Martelli, Alberto M, Montalto, Giuseppe, Emma, Maria Rita, Cervello, Melchiorre, Rakus, Dariusz, Gizak, Agnieszka, McCubrey, James A

“…The TP53 tumor suppressor is mutated in ~75% of pancreatic cancers. The mutant TP53 protein in pancreatic ductal adenocarcinomas (PDAC) promotes tumor growth…”
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The NUPR1/p73 axis contributes to sorafenib resistance in hepatocellular carcinoma by Augello, Giuseppa, Emma, Maria Rita, Azzolina, Antonina, Puleio, Roberto, Condorelli, Lucia, Cusimano, Antonella, Giannitrapani, Lydia, McCubrey, James A., Iovanna, Juan Lucio, Cervello, Melchiorre

“…The multikinase inhibitor sorafenib was the first drug approved by the FDA for treating patients with advanced hepatocellular carcinoma (HCC). However,…”
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Lipid nanocarriers containing sorafenib inhibit colonies formation in human hepatocarcinoma cells by Bondì, Maria Luisa, Botto, Chiara, Amore, Erika, Emma, Maria Rita, Augello, Giuseppa, Craparo, Emanuela Fabiola, Cervello, Melchiorre

“…[Display omitted] Here, the potential of two nanostructured lipid carriers (NLC) for controlled release of sorafenib was evaluated. The obtained systems showed…”
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Nanoparticles of a polyaspartamide-based brush copolymer for modified release of sorafenib: In vitro and in vivo evaluation by Cervello, Melchiorre, Pitarresi, Giovanna, Volpe, Antonella Bavuso, Porsio, Barbara, Balasus, Daniele, Emma, Maria Rita, Azzolina, Antonina, Puleio, Roberto, Loria, Guido Ruggero, Puleo, Stefano, Giammona, Gaetano

“…In this paper, we describe the preparation of polymeric nanoparticles (NPs) loaded with sorafenib for the treatment of hepatocellular carcinoma (HCC). A…”
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Synthetic peptide-labelled micelles for active targeting of cells overexpressing EGF receptors by Tesauro, Diego, Mastro, Raffaella, Cusimano, Antonella, Emma, Maria Rita, Cervello, Melchiorre

“…The goal of nanomedicine is to transport drugs to pathological tissues, reducing side effects while increasing targeting and efficacy. Aggregates grafted by…”
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Targeting HSP90 with the small molecule inhibitor AUY922 (luminespib) as a treatment strategy against hepatocellular carcinoma by Augello, Giuseppa, Emma, Maria Rita, Cusimano, Antonella, Azzolina, Antonina, Mongiovì, Sarah, Puleio, Roberto, Cassata, Giovanni, Gulino, Alessandro, Belmonte, Beatrice, Gramignoli, Roberto, Strom, Stephen C., McCubrey, James A., Montalto, Giuseppe, Cervello, Melchiorre

“…Hepatocellular carcinoma (HCC) is a highly malignant tumor that responds very poorly to existing therapies, most probably due to its extraordinary inter‐ and…”
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Preclinical evaluation of antitumor activity of the proteasome inhibitor MLN2238 (ixazomib) in hepatocellular carcinoma cells by Augello, Giuseppa, Modica, Martina, Azzolina, Antonina, Puleio, Roberto, Cassata, Giovanni, Emma, Maria Rita, Di Sano, Caterina, Cusimano, Antonella, Montalto, Giuseppe, Cervello, Melchiorre

“…Hepatocellular carcinoma (HCC) is one of the common malignancies and is an increasingly important cause of cancer death worldwide. Surgery, chemotherapy, and…”
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A PTEN inhibitor displays preclinical activity against hepatocarcinoma cells by Augello, Giuseppa, Puleio, Roberto, Emma, Maria Rita, Cusimano, Antonella, Loria, Guido R, McCubrey, James A, Montalto, Giuseppe, Cervello, Melchiorre

“…Phosphatase and tensin homolog (PTEN) gene is considered a tumor suppressor gene. However, PTEN mutations rarely occur in hepatocellular carcinoma (HCC),…”
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Association Between MICA Gene Variants and the Risk of Hepatitis C Virus-Induced Hepatocellular Cancer in a Sicilian Population Sample by Augello, Giuseppa, Balasus, Daniele, Fusilli, Caterina, Mazza, Tommaso, Emma, Maria Rita, Giannitrapani, Lydia, Agliastro, Rosalia, Cervello, Melchiorre, Montalto, Giuseppe

“…There are currently no biomarkers that predict hepatocellular carcinoma (HCC) risk in patients with hepatitis C virus (HCV)-related cirrhosis. We investigated…”
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Apoptosis and cell growth arrest in A375 human melanoma cells by diorganotin(IV) and triorganotin(IV) complexes of [meso-Tetra(4-sulfonatophenyl)porphine] manganese(III)chloride by ASSUNTA COSTA, Maria, ZITO, Francesca, EMMA, Maria Rita, PELLERITO, Lorenzo, FIORE, Tiziana, PELLERITO, Claudia, BARBIERI, Giovanna

“…In previous studies we have demonstrated that two derivatives of meso-Tetra(4-sulfonatophenyl)porphine (TPPS), (Bu2Sn)2TPPS and (Bu3Sn)4TPPS, cause apoptotic…”
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A PTEN inhibitor displays preclinical activity against hepatocarcinoma cells by Augello, Giuseppa, Puleio, Roberto, Emma, Maria Rita, Cusimano, Antonella, Loria, Guido R., McCubrey, James A., Montalto, Giuseppe, Cervello, Melchiorre

“…Phosphatase and tensin homolog (PTEN) gene is considered a tumor suppressor gene. However, PTEN mutations rarely occur in hepatocellular carcinoma (HCC),…”
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