Search Results - "Rissman, R A"

CSF1R-mediated myeloid cell depletion shifts the ratio of motor cortical excitatory to inhibitory neurons in a multiple system atrophy model by Gauer, C., Battis, K., Schneider, Y., Florio, J.B., Mante, M., Kim, H.Y., Rissman, R.A., Hoffmann, A., Winkler, J.

“…Motor cortical circuit functions depend on the coordinated fine-tuning of two functionally diverse neuronal populations: glutamatergic pyramidal neurons…”
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How Aspects of Collective Action Relate to Implementation of Cooperative Management Among Private Landowners by Frater, Haley E., Holsman, R. H., Van Deelen, T. R., Nack, R. R., Rissman, A. R.

“…Forested land is increasingly owned in small parcels by family forest owners who are becoming less likely to conduct the management which supports ecosystems,…”
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Intranasal Insulin Reduces White Matter Hyperintensity Progression in Association with Improvements in Cognition and CSF Biomarker Profiles in Mild Cognitive Impairment and Alzheimer’s Disease by Kellar, D., Lockhart, S. N., Aisen, P., Raman, R., Rissman, R. A., Brewer, J., Craft, Suzanne

“…Background Intranasally administered insulin has shown promise in both rodent and human studies in Alzheimer’s disease; however, both effects and mechanisms…”
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Meditation and vacation effects have an impact on disease-associated molecular phenotypes by Epel, E S, Puterman, E, Lin, J, Blackburn, E H, Lum, P Y, Beckmann, N D, Zhu, J, Lee, E, Gilbert, A, Rissman, R A, Tanzi, R E, Schadt, E E

“…Meditation is becoming increasingly practiced, especially for stress-related medical conditions. Meditation may improve cellular health; however, studies have…”
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Corticotropin-Releasing Factor Receptors Differentially Regulate Stress-Induced Tau Phosphorylation by Rissman, Robert A, Lee, Kuo-Fen, Vale, Wylie, Sawchenko, Paul E

“…Hyperphosphorylation of the microtubule-associated protein tau is a key event in the development of Alzheimer's disease (AD) neuropathology. Acute stress can…”
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Relationship between Plasma P-Tau217 and Amyloid PET in Racial and Ethnic Underrepresented Groups (RE-URG) Compared with Non RE-URG in LEARN and A4 by Molina-Henry, Doris, Langford, O., Donohue, M. C., Raman, R., Aisen, P., Johnson, K. A., Rissman, R. A., Sperling, R.

“…Background Individuals from diverse racial and ethnic groups are severely underrepresented in Alzheimer’s disease trials in part due to disproportionate…”
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Maximizing the Utility of Alzheimer’s Disease Trial Data: Sharing of Baseline A4 and LEARN Data by Jimenez-Maggiora, Gustavo A., Schulz, A. P., Donohue, M. C., Qiu, H., Jaiswal, S. N., Adegoke, O., Gallardo, R., Baryshnikava, O., Rissman, R. A., Abdel-Latif, S., Sperling, R. A., Aisen, P. S.

“…Background The Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Disease (A4) and Longitudinal Evaluation of Amyloid Risk and Neurodegeneration (LEARN)…”
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The Trial-Ready Cohort for Preclinical/Prodromal Alzheimer’s Disease (TRC-PAD) Project: An Overview by Aisen, P. S., Sperling, R. A., Cummings, J., Donohue, M. C., Langford, O., Jimenez-Maggiora, G. A., Rissman, R. A., Rafii, M. S., Walter, S., Clanton, T., Raman, R.

“…The Trial-Ready Cohort for Preclinical/prodromal Alzheimer’s Disease (TRC-PAD) project is a collaborative effort to establish an efficient mechanism for…”
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Longitudinal Phospho-tau217 Predicts Amyloid Positron Emission Tomography in Asymptomatic Alzheimer’s Disease by Rissman, Robert A., Donohue, M. C., Langford, O., Raman, R., Abdel-Latif, S., Yaari, R., Holdridge, K. C., Sims, J. R., Molina-Henry, D., Jimenez-Maggiora, G., Johnson, K. A., Aisen, P. S., Sperling, R. A.

“…Background Blood-based AD biomarkers such as plasma P-tau217 are increasingly used in clinical trials as a screening tool. Objectives To assess the utility of…”
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Amyloid and Tau Prediction of Cognitive and Functional Decline in Unimpaired Older Individuals: Longitudinal Data from the A4 and LEARN Studies by Sperling, Reisa A., Donohue, M. C., Rissman, R. A., Johnson, K. A., Rentz, D. M., Grill, J. D., Heidebrink, J. L., Jenkins, C., Jimenez-Maggiora, G., Langford, O., Liu, A., Raman, R., Yaari, R., Holdridge, K. C., Sims, J. R., Aisen, P. S.

“…Background Converging evidence suggests that markers of Alzheimer’s disease (AD) pathology in cognitively unimpaired older individuals are associated with high…”
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The AlzMatch Pilot Study - Feasibility of Remote Blood Collection of Plasma Biomarkers for Preclinical Alzheimer’s Disease Trials by Walter, Sarah, Langford, O., Jimenez-Maggiora, G. A., Abdel-Latif, S., Rissman, R. A., Grill, J. D., Karlawish, J., Atri, A., Bruschi, S., Hussen, K., Donohue, M. C., Marshall, G. A., Jicha, G., Racke, M., Turner, R. S., van Dyck, C. H., Venkatesh, V., Yarasheski, K. E., Sperling, R., Cummings, J., Aisen, P. S., Raman, R.

“…Background Advances in plasma biomarkers to detect Alzheimer’s disease (AD) biology allows researchers to improve the efficiency of participant recruitment…”
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The Role of Caspase Cleavage of Tau in Alzheimer Disease Neuropathology by Cotman, Carl W, Poon, Wayne W, Rissman, Robert A, Blurton-Jones, Mathew

“…Alzheimer disease (AD) is characterized by the accumulation of amyloid plaques and neurofibrillary tangles within selective brain regions. In addition, cell…”
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Urocortin Expression in Rat Brain: Evidence Against a Pervasive Relationship of Urocortin-Containing Projections With Targets Bearing Type 2 CRF Receptors by Bittencourt, Jackson C., Vaughan, Joan, Arias, Carlos, Rissman, Robert A., Vale, Wylie W., Sawchenko, Paul E.

“…Histochemical and axonal transport methods were used to clarify the central organization of cells and fibers that express urocortin (UCN), a recently…”
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The distribution of melanin-concentrating hormone in the monkey brain ( Cebus apella) by Bittencourt, Jackson C, Frigo, Lúcio, Rissman, Robert A, Casatti, Cláudio A, Nahon, Jean-Louis, Bauer, Jarbas A

“…Melanin-concentrating hormone was identified in the brain of Cebus monkey using immunohistochemical and in situ hybridization. MCH-immunoreactive neurons were…”
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Biochemical analysis of GABAA receptor subunits α1, α5, β1, β2 in the hippocampus of patients with Alzheimer's disease neuropathology by RISSMAN, R. A, MISHIZEN-EBERZ, A. J, CARTER, T. L, WOLFE, B. B, DE BLAS, A. L, MIRALLES, C. P, IKONOMOVIC, M. D, ARMSTRONG, D. M

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Biochemical analysis of GABA(A) receptor subunits alpha 1, alpha 5, beta 1, beta 2 in the hippocampus of patients with Alzheimer's disease neuropathology by Rissman, R A, Mishizen-Eberz, A J, Carter, T L, Wolfe, B B, De Blas, A L, Miralles, C P, Ikonomovic, M D, Armstrong, D M

“…Alzheimer's disease (AD) is characterized by selective vulnerability of specific neuronal populations within particular brain regions. For example, hippocampal…”
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Plasma biomarkers for Alzheimer’s Disease in relation to neuropathology and cognitive change by Smirnov, Denis S., Ashton, Nicholas J., Blennow, Kaj, Zetterberg, Henrik, Simrén, Joel, Lantero-Rodriguez, Juan, Karikari, Thomas K., Hiniker, Annie, Rissman, Robert A., Salmon, David P., Galasko, Douglas

“…Plasma biomarkers related to amyloid, tau, and neurodegeneration (ATN) show great promise for identifying these pathological features of Alzheimer’s Disease…”
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Ecological worldview, agricultural or natural resource-based activities, and geography affect perceived importance of ecosystem services by Wardropper, C.B., Mase, A.S., Qiu, J., Kohl, P., Booth, E.G., Rissman, A.R.

“…•All ecosystem services were rated at least "somewhat important" on average.•Females and those working in agriculture gave agricultural ES high…”
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Learnings about the complexity of extracellular tau aid development of a blood-based screen for Alzheimer's disease by Chen, Zhicheng, Mengel, David, Keshavan, Ashvini, Rissman, Robert A., Billinton, Andrew, Perkinton, Michael, Percival-Alwyn, Jennifer, Schultz, Aaron, Properzi, Michael, Johnson, Keith, Selkoe, Dennis J., Sperling, Reisa A., Patel, Purvish, Zetterberg, Henrik, Galasko, Douglas, Schott, Jonathan M., Walsh, Dominic M.

“…The tau protein plays a central role in Alzheimer's disease (AD), and there is huge interest in measuring tau in blood and cerebrospinal fluid (CSF). We…”
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Comparing biological markers of Alzheimer's disease across blood fraction and platforms: Comparing apples to oranges by O'Bryant, Sid E, Lista, Simone, Rissman, Robert A, Edwards, Melissa, Zhang, Fan, Hall, James, Zetterberg, Henrik, Lovestone, Simon, Gupta, Veer, Graff-Radford, Neill, Martins, Ralph, Jeromin, Andreas, Waring, Stephen, Oh, Esther, Kling, Mitchel, Baker, Laura D, Hampel, Harald

“…Abstract Introduction This study investigated the comparability of potential Alzheimer's disease (AD) biomarkers across blood fractions and assay platforms…”
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