Search Results - "Riss, L."

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  1. 1

    Use of multiple assay endpoints to investigate the effects of incubation time, dose of toxin, and plating density in cell-based cytotoxicity assays by Riss, Terry L, Moravec, Richard A

    Published in Assay and drug development technologies (01-02-2004)
    “…Here we show the results of comparing cell viability, cytotoxicity, and apoptosis assays for measuring the time- and dose-dependent toxic effects of tamoxifen…”
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  2. 2

    Cell-based bioluminescent assays for all three proteasome activities in a homogeneous format by Moravec, Richard A., O’Brien, Martha A., Daily, William J., Scurria, Michael A., Bernad, Laurent, Riss, Terry L.

    Published in Analytical biochemistry (15-04-2009)
    “…A luminescent method to individually measure the chymotrypsin-like, trypsin-like, or caspase-like activities of the proteasome in cultured cells was developed…”
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  3. 3

    New Bioluminogenic Substrates for Monoamine Oxidase Assays by Zhou, Wenhui, Valley, Michael P, Shultz, John, Hawkins, Erika M, Bernad, Laurent, Good, Troy, Good, Dave, Riss, Terry L, Klaubert, Dieter H, Wood, Keith V

    Published in Journal of the American Chemical Society (15-03-2006)
    “…Novel bioluminogenic substrates were designed for probing monoamine oxidase (MAO) activity based on a simple and effective β-elimination strategy. By modifying…”
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  4. 4

    Poly (ADP-ribose) polymerase cleavage monitored in situ in apoptotic cells by O'Brien, M A, Moravec, R A, Riss, T L

    Published in BioTechniques (01-04-2001)
    “…During apoptosis, the activation of a family of cysteine proteases, or caspases, results in proteolytic cleavage of numerous substrates. Antibody probes…”
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  5. 5

    "Multiplexed viability, cytotoxicity, and caspase activity assays" by Niles, Andrew L, Riss, Terry L

    “…Multiplexed assay chemistries provide for multiple measurements of cellular parameters within a single assay well. This experimental practice is not only more…”
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  6. 6

    Applying spaced practice in the schools to teach math vocabulary by Petersen‐Brown, Shawna, Lundberg, Ashlee R., Ray, Jannine E., Dela Paz, Iwalani N., Riss, Carrington L., Panahon, Carlos J.

    Published in Psychology in the schools (01-06-2019)
    “…Spaced practice, or the distribution of practice opportunities across time, is a well‐known and effective practice for improving retention. However, spaced…”
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  7. 7

    Treating Cells as Reagents to Design Reproducible Assays by Riss, Terry L, Moravec, Richard A, Duellman, Sarah J, Niles, Andrew L

    Published in SLAS discovery (01-12-2021)
    “…The reproducibility of high-throughput cell-based assays is dependent on having a consistent source of cells for each experiment. Developing an understanding…”
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  8. 8

    Apoptosis as a biomarker in chemoprevention trials by Riss, Terry L

    Published in Urology (Ridgewood, N.J.) (01-04-2001)
    “…Monitoring apoptosis in histologic samples is becoming increasingly important as more effort is applied to the study of therapeutic modulators of cell death in…”
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  9. 9

    A homogeneous assay to measure live and dead cells in the same sample by detecting different protease markers by Niles, Andrew L., Moravec, Richard A., Eric Hesselberth, P., Scurria, Michael A., Daily, William J., Riss, Terry L.

    Published in Analytical biochemistry (15-07-2007)
    “…A method to simultaneously determine the relative numbers of live and dead cells in culture by introducing a combination of two fluorogenic substrates or a…”
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  10. 10

    Calcium alginate beads as a slow-release system for delivering angiogenic molecules in vivo and in vitro by Downs, E C, Robertson, N E, Riss, T L, Plunkett, M L

    Published in Journal of cellular physiology (01-08-1992)
    “…A method previously used in this laboratory for entrapment of tumor cells in alginate beads has been extended to provide a slow release delivery system for…”
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  11. 11

    In vitro viability and cytotoxicity testing and same-well multi-parametric combinations for high throughput screening by Niles, Andrew L, Moravec, Richard A, Riss, Terry L

    Published in Current chemical genomics (11-06-2009)
    “…In vitro cytotoxicity testing has become an integral aspect of drug discovery because it is a convenient, costeffective, and predictive means of characterizing…”
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  12. 12

    Cytotoxicity testing: measuring viable cells, dead cells, and detecting mechanism of cell death by Riss, Terry L, Moravec, Richard A, Niles, Andrew L

    “…Testing the effects of compounds on the viability of cells grown in culture is widely used as a predictor of potential toxic effects in whole animals. Among…”
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    Bioluminescent assays for ADMET by Cali, James J, Niles, Andrew, Valley, Michael P, O'Brien, Martha A, Riss, Terry L, Shultz, John

    “…Bioluminescent assays couple a limiting component of a luciferase-catalyzed photon-emitting reaction to a variable parameter of interest, while holding the…”
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  17. 17

    A bioluminescent assay for monoamine oxidase activity by Valley, Michael P., Zhou, Wenhui, Hawkins, Erika M., Shultz, John, Cali, James J., Worzella, Tracy, Bernad, Laurent, Good, Troy, Good, Dave, Riss, Terry L., Klaubert, Dieter H., Wood, Keith V.

    Published in Analytical biochemistry (15-12-2006)
    “…This article describes a novel two-step homogeneous bioluminescent assay for monoamine oxidase (MAO) that is simple, sensitive, and amenable to high-throughput…”
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  18. 18

    Homogeneous, bioluminescent proteasome assays by O'Brien, Martha A, Moravec, Richard A, Riss, Terry L, Bulleit, Robert F

    “…Protein degradation is mediated predominantly through the ubiquitin-proteasome pathway. The importance of the proteasome in regulating degradation of proteins…”
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  19. 19

    Growth and continuous passage of COMMA-D mouse mammary epithelial cells in hormonally defined serum-free medium by RISS, T. L, SIRBASKU, D. A

    Published in Cancer research (Chicago, Ill.) (15-07-1987)
    “…Growth of the mouse mammary epithelial cell line designated COMMA-D has been studied in serum-free medium (SFM) formulated with Ham's F12 and Dulbecco's…”
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  20. 20

    Characterization of polyclonal antibodies that distinguish acidic and basic fibroblast growth factors by using western immunoblotting and enzyme-linked immunosorbent assays by Riss, T L, Sirbasku, D A

    Published in Journal of cellular physiology (01-02-1989)
    “…Rabbit polyclonal antibodies were raised against ovalbumin conjugates of purified bovine brain acidic fibroblast growth factor (aFGF) and a synthetic peptide…”
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