Search Results - "Risner, Marcus E."

The tolerability of lamotrigine in children by MESSENHEIMER, J. A, GIORGI, L, RISNER, M. E

“…Lamotrigine is a novel anticonvulsant, which has proven to be effective both as add-on and monotherapy. 13 studies have demonstrated efficacy in 1096 children…”
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Population Pharmacokinetics of Lamotrigine Adjunctive Therapy in Adults with Epilepsy by Grasela, Thaddeus H., Fiedler-Kelly, Jill, Cox, Eugène, Womble, Gilda P., Risner, Marcus E., Chen, Chao

“…Plasma concentrations of lamotrigine, an antiepileptic drug obtained in three adult controlled clinical trials conducted in the United States were pooled and…”
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Lamotrigine high-dose tolerability and safety in patients with epilepsy: a double-blind, placebo-controlled, eleven-week study by Matsuo, F, Gay, P, Madsen, J, Tolman, K G, Rollins, D E, Risner, M E, Lai, A A

“…This study was undertaken to evaluate the dose tolerability and safety of a chronic ascending twice-daily (b.i.d.) dosage regimen of < or = 700 mg/day…”
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Incompleteness of Lamotrigine Data: The Author??s Reply by Messenheimer, John A., Risner, Marcus E., Giorgi, Luigi

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Population Pharmacokinetics of Lamotrigine Adjunctive Therapy in Adults with Epilepsy by Grasela, Thaddeus H, Fiedler-Kelly, Jill, Cox, Eugene, Womble, Gilda P, Risner, Marcus E, Chen, Chao

“…Plasma concentrations of lamotrigine, an antiepileptic drug obtained in three adult controlled clinical trials conducted in the United States were pooled and…”
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Incompleteness of lamotrigine data. Authors' reply by ACHARYA, Nanyan V, WILTON, Linda V, SHAKIR, Saad A, MESSENHEIMER, John A, RISNER, Marcus E, GIORGI, Luigi

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Nicotine and some related compounds: effects on schedule-controlled behaviour and discriminative properties in rats by Goldberg, S R, Risner, M E, Stolerman, I P, Reavill, C, Garcha, H S

“…Behavioural effects of d- and l-nicotine, d- and l-nornicotine and l-cotinine were studied in two paradigms. In experiment 1, rats responded under a multiple…”
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Effects of L-cocaine on local cerebral glucose utilization in the rat by London, E D, Wilkerson, G, Goldberg, S R, Risner, M E

“…The 2-deoxy-D-[l-14C]glucose method was used to map the in vivo metabolic response (local cerebral glucose utilization. LCGU) to L-cocaine in the rat brain…”
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Intravenous self-administration of fencamfamine and cocaine by beagle dogs under fixed-ratio and progressive-ratio schedules of reinforcement by Risner, M E, Cone, E J

“…Catheterized beagle dogs were given access to response-contingent intravenous injections of fencamfamine (FEN) or cocaine (COC) injections under a fixed-ratio…”
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Disposition kinetics of nicotine and cotinine enantiomers in rabbits and beagle dogs by Jacob, 3rd, P, Benowitz, N L, Copeland, J R, Risner, M E, Cone, E J

“…The disposition kinetics of nicotine and cotinine enantiomers was determined in rabbits. The clearance of (R)-nicotine was similar to that of (S)-nicotine, but…”
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Control of behavior by intravenous nicotine injections in laboratory animals by Goldberg, S R, Spealman, R D, Risner, M E, Henningfield, J E

“…A series of recent studies are reviewed which demonstrate that behavior can be controlled by nicotine injections in different ways depending on the behavioral…”
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Opiate receptor supersensitivity produced by chronic naloxone treatment: dissociation of morphine-induced antinociception and conditioned taste aversion by Bardo, M T, Miller, J S, Risner, M E

“…In three separate experiments, rats were used to assess the effects of chronic administration of naloxone on specific binding of 3H-naloxone in various regions…”
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Pharmacologic and reinforcing properties of phencyclidine and the enantiomers of N-allylnormetazocine in the dog by Vaupel, D B, Risner, M E, Shannon, H E

“…Experiments were conducted to evaluate the degree of phencyclidine (PCP)-like activity associated with the dextro and levo enantiomers of the sigma agonist…”
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Behavioral effects of CGS 8216 alone, and in combination with diazepam and pentobarbital in dogs by Risner, M E, Shannon, H E

“…Beagle dogs (N = 3) responded under a multiple fixed-interval (FI) 300 sec, fixed-ratio (FR) 30 schedule of food presentation. The pyrazoloquinoline derivative…”
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Discriminative stimulus properties and schedule effects of fencamfamine in rats by Risner, M E, Jackson-Smith, P A, Cone, E J

“…The behavioral properties of fencamfamine, a sympathomimetic central stimulant recently identified in alleged cocaine samples, were studied in two different…”
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