Search Results - "Risa Korenaga"
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Cloning of cDNAs Encoding G Protein-Coupled Receptor Expressed in Human Endothelial Cells Exposed to Fluid Shear Stress
Published in Biochemical and biophysical research communications (26-11-1997)“…A cDNA library of human umbilical vein endothelial cells exposed to fluid shear stress was constructed to search for functional endothelial genes expressed…”
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Fluid Shear Stress Transcriptionally Induces Lectin-like Oxidized LDL Receptor-1 in Vascular Endothelial Cells
Published in Circulation research (10-08-1998)“…Fluid shear stress has been shown to modulate various endothelial functions, including gene expression. In this study, we examined the effect of fluid shear…”
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Endothelial Ca2+Waves Preferentially Originate at Specific Loci in Caveolin-Rich Cell Edges
Published in Proceedings of the National Academy of Sciences - PNAS (28-04-1998)“…Stimulation of endothelial cells (ECs) with ATP evoked an increase in intracellular Ca2+concentration ([Ca2+]i). In a single bovine aortic EC, the [Ca2+]irise…”
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Shear Stress Augments Expression of C-Type Natriuretic Peptide and Adrenomedullin
Published in Hypertension (Dallas, Tex. 1979) (01-06-1997)“…Shear stress is known to dilate blood vessels and exert antiproliferative effects on vascular walls; these effects have been ascribed to shear stress-induced…”
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Negative transcriptional regulation of the VCAM-1 gene by fluid shear stress in murine endothelial cells
Published in The American journal of physiology (01-11-1997)“…To explore the mechanism of shear stress-induced downregulation of vascular cell adhesion molecule 1 (VCAM-1) expression in murine endothelial cells (ECs), we…”
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Fluid Shear Stress Increases the Production of Granulocyte-Macrophage Colony-Stimulating Factor by Endothelial Cells via mRNA Stabilization
Published in Circulation research (20-04-1998)“…To investigate whether the production of colony-stimulating factors (CSFs) by vascular endothelial cells is regulated by hemodynamic force, we exposed cultured…”
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Contribution of Sustained Ca Elevation for Nitric Oxide Production in Endothelial Cells and Subsequent Modulation of Ca Transient in Vascular Smooth Muscle Cells in Coculture
Published in The Journal of biological chemistry (08-03-1996)“…To elucidate the intracellular Ca (Ca ) transient responsible for nitric oxide (NO) production in endothelial cells (ECs) and the subsequent Ca reduction in…”
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Contribution of Sustained Ca2+ Elevation for Nitric Oxide Production in Endothelial Cells and Subsequent Modulation of Ca2+ Transient in Vascular Smooth Muscle Cells in Coculture (∗)
Published in The Journal of biological chemistry (08-03-1996)“…To elucidate the intracellular Ca2+ (Ca2+i) transient responsible for nitric oxide (NO) production in endothelial cells (ECs) and the subsequent Ca2+i…”
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Physiologic Shear Stress Suppresses Endothelin-Converting Enzyme-1 Expression in Vascular Endothelial Cells
Published in Journal of cardiovascular pharmacology (1998)“…Shear stress dilates blood vessels and exerts an antiproliferative effect on vascular walls. These effects are ascribed to shear stress-induced,…”
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Fluid Shear Stress Activates Ca2+ Influx Into Human Endothelial Cells via P2X4 Purinoceptors
Published in Circulation research (01-09-2000)“…Ca signaling plays an important role in endothelial cell (EC) responses to shear stress generated by blood flow. Our previous studies demonstrated that bovine…”
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Fluid shear stress activates Ca(2+) influx into human endothelial cells via P2X4 purinoceptors
Published in Circulation research (01-09-2000)“…Ca(2+) signaling plays an important role in endothelial cell (EC) responses to shear stress generated by blood flow. Our previous studies demonstrated that…”
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Close Correlation between Cytoplasmic Ca++ Levels and Release of an Endothelium-Derived Relaxing Factor from Cultured Endothelial Cells
Published in Cell Structure and Function (1993)“…We studied whether there is a quantitative relationship between free cytosolic Ca++ levels and the release of an endothelium-derived relaxing factor (EDRF)…”
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13
Sp1-mediated downregulation of P2X4 receptor gene transcription in endothelial cells exposed to shear stress
Published in American journal of physiology. Heart and circulatory physiology (01-05-2001)“…Endothelial purinoceptors play an important role in vascular responses to extracellular adenine nucleotides and hemodynamic forces. Here we report that P2X4…”
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Fluid Shear Stress Activates Ca 2+ Influx Into Human Endothelial Cells via P2X4 Purinoceptors
Published in Circulation research (01-09-2000)“…Abstract —Ca 2+ signaling plays an important role in endothelial cell (EC) responses to shear stress generated by blood flow. Our previous studies demonstrated…”
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15
Fluid shear stress increases the expression of thrombomodulin by cultured human endothelial cells
Published in Biochemical and biophysical research communications (15-12-1994)“…Endothelial cells (ECs) cultured from human umbilical vein were exposed to medium flow in a flow-loading chamber, and changes in thrombomodulin (TM) expression…”
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Exogenous nitric oxide inhibits proliferation of cultured vascular endothelial cells
Published in Biochemical and biophysical research communications (15-09-1994)“…Cultured bovine fatal aortic endothelial cells (BAECs) were stimulated with nitric oxide (NO)-releasing vasodilators and NO gas-saturated solution, and changes…”
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Flow Stimulates ICAM-1 Expression Time and Shear Stress Dependently in Cultured Human Endothelial Cells
Published in Biochemical and biophysical research communications (26-01-1995)“…Human umbilical vein endothelial cells were subjected to controlled levels of shear stress in a flow-loading apparatus, and changes in the expression of…”
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18
Laminar flow stimulates ATP- and shear stress-dependent nitric oxide production in cultured bovine endothelial cells
Published in Biochemical and biophysical research communications (14-01-1994)“…Based on the fact that nitric oxide (NO) production is associated with changes in intracellular cGMP levels and is selectively inhibited by N omega-methyl…”
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Wall shear stress rather than shear rate regulates cytoplasmic Ca++ responses to flow in vascular endothelial cells
Published in Biochemical and biophysical research communications (15-02-1993)“…Recent evidence suggests that the vascular endothelial cell (EC) can sense the flow-rate over its surface and according to the information, regulates not only…”
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Effect of extracellular ATP level on flow-induced Ca++ response in cultured vascular endothelial cells
Published in Biochemical and biophysical research communications (30-09-1991)“…Cultured vascular endothelial cells loaded with the highly fluorescent Ca(++)-sensitive dye Fura-2 were exposed to the flow of a fluid containing various…”
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