Search Results - "Risør, Michael Wulff"
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How internal cavities destabilize a protein
Published in Proceedings of the National Academy of Sciences - PNAS (15-10-2019)“…Although many proteins possess a distinct folded structure lying at a minimum in a funneled free energy landscape, thermal energy causes any protein to…”
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Journal Article -
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Reactive Center Loop Insertion in α‑1-Antitrypsin Captured by Accelerated Molecular Dynamics Simulation
Published in Biochemistry (Easton) (31-01-2017)“…Protease inhibition by metastable serine protease inhibitors (serpins) is mediated by one of the largest functional intradomain conformational changes known in…”
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Conservation of the Amyloid Interactome Across Diverse Fibrillar Structures
Published in Scientific reports (07-03-2019)“…Several human proteins cause disease by misfolding and aggregating into amyloid fibril deposits affecting the surrounding tissues. Multiple other proteins…”
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Journal Article