Search Results - "Riquelme, Luis A."
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1
Visuomotor Adaptation Modulates the Clustering of Sleep Spindles Into Trains
Published in Frontiers in neuroscience (16-03-2022)“…Sleep spindles are thought to promote memory consolidation. Recently, we have shown that visuomotor adaptation (VMA) learning increases the density of spindles…”
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2
Turning off cortical ensembles stops striatal Up states and elicits phase perturbations in cortical and striatal slow oscillations in rat in vivo
Published in The Journal of physiology (15-11-2006)“…In vivo , cortical neurons and striatal medium spiny neurons (MSN) display robust subthreshold depolarizations (Up states) during which they are enabled to…”
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3
Striatal NMDA receptors gate cortico-pallidal synchronization in a rat model of Parkinson's disease
Published in Neurobiology of disease (01-07-2012)“…Abstract Anomalous patterns of synchronization between basal ganglia and cortex underlie the symptoms of Parkinson's disease. Computational modeling studies…”
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4
Motor Learning Promotes the Coupling between Fast Spindles and Slow Oscillations Locally over the Contralateral Motor Network
Published in Cerebral cortex (New York, N.Y. 1991) (07-06-2022)“…Abstract Recent studies from us and others suggest that traditionally declarative structures mediate some aspects of the encoding and consolidation of…”
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5
Functional integration across a gradient of corticostriatal channels controls UP state transitions in the dorsal striatum
Published in Proceedings of the National Academy of Sciences - PNAS (10-06-2008)“…Coordinated near-threshold depolarized states in cortical and striatal neurons may contribute to form functionally segregated channels of information…”
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6
Disruption of the two-state membrane potential of striatal neurones during cortical desynchronisation in anaesthetised rats
Published in The Journal of physiology (01-09-2002)“…In anaesthetised animals, the very negative resting membrane potential of striatal spiny neurones (down state) is interrupted periodically by depolarising…”
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7
NMDA Receptor Gating of Information Flow through the Striatum In Vivo
Published in The Journal of neuroscience (10-12-2008)“…A role of NMDA receptors in corticostriatal synaptic plasticity is widely acknowledged. However, the conditions that allow NMDA receptor activation in the…”
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8
Cortical Slow Oscillatory Activity Is Reflected in the Membrane Potential and Spike Trains of Striatal Neurons in Rats with Chronic Nigrostriatal Lesions
Published in The Journal of neuroscience (15-08-2001)“…Neurons in the basal ganglia output nuclei display rhythmic burst firing after chronic nigrostriatal lesions. The thalamocortical network is a strong…”
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9
Nigrostriatal lesion induces D2-modulated phase-locked activity in the basal ganglia of rats
Published in The European journal of neuroscience (01-04-2007)“…There is a debate as to what modifications of neuronal activity underlie the clinical manifestations of Parkinson's disease and the efficacy of…”
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10
Distinct changes in evoked and resting globus pallidus activity in early and late Parkinson's disease experimental models
Published in The European journal of neuroscience (01-09-2007)“…The main clinical manifestations of Parkinson's disease are caused by alterations of basal ganglia activity that are tied in with the progressive loss of…”
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11
Consequences of partial and severe dopaminergic lesion on basal ganglia oscillatory activity and akinesia
Published in The European journal of neuroscience (01-11-2005)“…Severe chronic dopamine (DA) depletion increases the proportion of neurons in the basal ganglia that fire rhythmic bursts of action potential (LFO units)…”
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12
Striatal dysfunction increases basal ganglia output during motor cortex activation in parkinsonian rats
Published in The European journal of neuroscience (01-05-2007)“…During movement, inhibitory neurons in the basal ganglia output nuclei show complex modulations of firing, which are presumptively driven by corticostriatal…”
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13
Striatal gating through up states and oscillations in the basal ganglia: Implications for Parkinson’s disease
Published in Journal of physiology, Paris (01-01-2012)“…► We propose a model for understanding up state physiology in striatal neurons and the pathophysiology of Parkinson’s disease. ► D2 and NMDA receptors regulate…”
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14
Spreading of slow cortical rhythms to the basal ganglia output nuclei in rats with nigrostriatal lesions
Published in The European journal of neuroscience (01-03-2003)“…A high proportion of neurons in the basal ganglia display rhythmic burst firing after chronic nigrostriatal lesions. For instance, the periodic bursts…”
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15
Subthalamic nucleus lesions reduce low frequency oscillatory firing of substantia nigra pars reticulata neurons in a rat model of Parkinson’s disease
Published in Brain research (15-06-2001)“…Single unit recordings performed in animal models of Parkinson’s disease revealed that output nuclei neurons display modifications in firing pattern and firing…”
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Substantia nigra pars reticulata units in 6-hydroxydopamine-lesioned rats: responses to striatal D2 dopamine receptor stimulation and subthalamic lesions
Published in The European journal of neuroscience (01-01-2000)“…In order to increase our understanding of Parkinson's disease pathophysiology, we studied the effects of intrastriatally administered selective dopamine…”
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17
D1–D2 dopamine receptor interaction: an in vivo single unit electrophysiological study
Published in Neuroreport (10-02-1997)“…AFTER intrastriatal administration of selective dopamine receptor agonists only a small percentage of substantia nigra pars reticulata single units showed…”
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18
Substantia nigra pars reticulata single unit activity in normal and 60HDA-lesioned rats: Effects of intrastriatal apomorphine and subthalamic lesions
Published in Synapse (New York, N.Y.) (01-12-1997)“…The spontaneous activity and the response to intrastriatal application of apomorphine of substantia nigra pars reticulata (SNpr) single units was studied in…”
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19
Role of the mesopontine area in the circling behavior induced by apomorphine in rats bearing unilateral lesion of the entopeduncular nucleus
Published in Behavioural brain research (25-10-1991)“…The role of the mesopontine area and superior colliculus in turning behavior induced by systemic administration of apomorphine was studied in rats bearing a…”
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