Search Results - "Riquelme, Cecilia"
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Fatty Acids Identified in the Burmese Python Promote Beneficial Cardiac Growth
Published in Science (American Association for the Advancement of Science) (28-10-2011)“…Burmese pythons display a marked increase in heart mass after a large meal. We investigated the molecular mechanisms of this physiological heart growth with…”
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Burmese pythons exhibit a transient adaptation to nutrient overload that prevents liver damage
Published in The Journal of general physiology (04-04-2022)“…As an opportunistic predator, the Burmese python (Python molurus bivittatus) consumes large and infrequent meals, fasting for up to a year. Upon consuming a…”
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ACE2 is augmented in dystrophic skeletal muscle and plays a role in decreasing associated fibrosis
Published in PloS one (01-04-2014)“…Duchenne muscular dystrophy (DMD) is the most common inherited neuromuscular disease and is characterized by absence of the cytoskeletal protein dystrophin,…”
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Novel and optimized strategies for inducing fibrosis in vivo: focus on Duchenne Muscular Dystrophy
Published in Skeletal muscle (25-08-2014)“…Fibrosis, an excessive collagen accumulation, results in scar formation, impairing function of vital organs and tissues. Fibrosis is a hallmark of muscular…”
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Palmitic Acid Reduces the Autophagic Flux and Insulin Sensitivity Through the Activation of the Free Fatty Acid Receptor 1 (FFAR1) in the Hypothalamic Neuronal Cell Line N43/5
Published in Frontiers in endocrinology (Lausanne) (26-03-2019)“…Chronic consumption of high fat diets (HFDs), rich in saturated fatty acids (SatFAs) like palmitic acid (PA), is associated with the development of obesity and…”
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Transforming growth factor type beta 1 increases the expression of angiotensin II receptor type 2 by a SMAD- and p38 MAPK-dependent mechanism in skeletal muscle
Published in BioFactors (Oxford) (01-07-2013)“…Excessive deposition of extracellular matrix (ECM) proteins, a condition known as fibrosis, is a hallmark of Duchenne muscular dystrophy. Among the factors…”
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Whole transcriptome analysis of the fasting and fed Burmese python heart: insights into extreme physiological cardiac adaptation
Published in Physiological genomics (01-01-2011)“…The infrequently feeding Burmese python (Python molurus) experiences significant and rapid postprandial cardiac hypertrophy followed by regression as digestion…”
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Ubc9 expression is essential for myotube formation in C2C12
Published in Experimental cell research (01-07-2006)“…Myogenic differentiation is a fundamental biological process that involves a hierarchical series of events that ultimately leads to muscle-specific gene…”
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Using Telenephrology to Improve Access to Nephrologist and Global Kidney Management of CKD Primary Care Patients
Published in Kidney international reports (01-06-2020)Get full text
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Extracellular proteoglycans modify TGF-β bio-availability attenuating its signaling during skeletal muscle differentiation
Published in Matrix biology (01-08-2006)“…The onset and progression of skeletal muscle regeneration are controlled by a complex set of interactions between muscle precursor cells and their environment…”
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Betaglycan Expression Is Transcriptionally Up-regulated during Skeletal Muscle Differentiation
Published in The Journal of biological chemistry (03-01-2003)“…Betaglycan is a membrane-anchored proteoglycan co-receptor that binds transforming growth factor β (TGF-β) via its core protein and basic fibroblast growth…”
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Structure of p300 bound to MEF2 on DNA reveals a mechanism of enhanceosome assembly
Published in Nucleic acids research (01-05-2011)“…Transcription co-activators CBP and p300 are recruited by sequence-specific transcription factors to specific genomic loci to control gene expression. A highly…”
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Transforming growth factor type-β inhibits Mas receptor expression in fibroblasts but not in myoblasts or differentiated myotubes; Relevance to fibrosis associated to muscular dystrophies
Published in BioFactors (Oxford) (01-03-2015)“…Duchenne muscular dystrophy is a genetic disorder characterized by myofiber degeneration, muscle weakness, and increased fibrosis. Transforming growth factor…”
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Morphological and molecular development in python model of pathological cardiac hypertrophy
Published in The FASEB journal (01-04-2010)“…The Burmese python (Python molurus) experiences rapid physiological hypertrophy of the heart with feeding. Within days after consuming a meal equaling in mass…”
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Python model of physiological and pathological hypertrophy
Published in The FASEB journal (01-04-2009)“…Abstract only…”
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Transcriptional regulation of metabolic genes in the postprandial python heart: an extreme example of physiologic adaptation
Published in The FASEB journal (01-04-2010)“…In order to cope with the physiologic stresses of digesting large meals, the heart of the Burmese python undergoes significant hypertrophy in as little as 24…”
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SUMO‐1 modification of MEF2A regulates its transcriptional activity
Published in Journal of cellular and molecular medicine (01-01-2006)“…Myocyte enhancer factor 2 (MEF2) transcription factors are crucial regulators controlling muscle‐specific and growth factor‐inducible genes. Numerous studies…”
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ACE2 Is Augmented in Dystrophic Skeletal Muscle and Plays a Role in Decreasing Associated Fibrosis: e93449
Published in PloS one (01-04-2014)“…Duchenne muscular dystrophy (DMD) is the most common inherited neuromuscular disease and is characterized by absence of the cytoskeletal protein dystrophin,…”
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Antisense Inhibition of Decorin Expression in Myoblasts Decreases Cell Responsiveness to Transforming Growth Factor β and Accelerates Skeletal Muscle Differentiation
Published in The Journal of biological chemistry (02-02-2001)“…Decorin is a member of the family of the small leucine-rich proteoglycans. In addition to its function as an extracellular matrix organizer, it has the ability…”
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