Search Results - "Ripperger, Jürgen A."
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Circadian Clocks and Sleep: Impact of Rhythmic Metabolism and Waste Clearance on the Brain
Published in Trends in neurosciences (Regular ed.) (01-10-2018)“…The rotation of the Earth around its axis causes periodic exposure of half of its surface to sunlight. This daily recurring event has been internalized in most…”
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Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions
Published in Nature genetics (01-03-2006)“…Mammalian circadian rhythms are based on transcriptional and post-translational feedback loops. Essentially, the activity of the transcription factors BMAL1…”
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3
Light affects behavioral despair involving the clock gene Period 1
Published in PLoS genetics (08-07-2021)“…Light at night has strong effects on physiology and behavior of mammals. It affects mood in humans, which is exploited as light therapy, and has been shown to…”
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Liver-derived ketone bodies are necessary for food anticipation
Published in Nature communications (03-02-2016)“…The circadian system has endowed animals with the ability to anticipate recurring food availability at particular times of day. As daily food anticipation (FA)…”
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Delay in Feedback Repression by Cryptochrome 1 Is Required for Circadian Clock Function
Published in Cell (21-01-2011)“…Direct evidence for the requirement of delay in feedback repression in the mammalian circadian clock has been elusive. Cryptochrome 1 ( Cry1), an essential…”
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Deletion of the clock gene Period2 (Per2) in glial cells alters mood-related behavior in mice
Published in Scientific reports (10-06-2021)“…The circadian clock regulates many biochemical and physiological pathways, and lack of clock genes, such as Period ( Per ) 2, affects not only circadian…”
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PER2 mediates CREB-dependent light induction of the clock gene Per1
Published in Scientific reports (05-11-2021)“…Light affects many physiological processes in mammals such as entrainment of the circadian clock, regulation of mood, and relaxation of blood vessels. At the…”
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Circadian rhythms govern cardiac repolarization and arrhythmogenesis
Published in Nature (London) (22-02-2012)“…Circadian rhythmicity of cardiac ion-channel expression and of an index of myocardial repolarization is under the control of Klf15, a clock-dependent…”
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The nuclear receptor REV-ERBα regulates Fabp7 and modulates adult hippocampal neurogenesis
Published in PloS one (16-06-2014)“…The function of the nuclear receptor Rev-erbα (Nr1d1) in the brain is, apart from its role in the circadian clock mechanism, unknown. Therefore, we compared…”
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The daily rhythm of mice
Published in FEBS letters (20-05-2011)“…The house mouse Mus musculus represents a valuable tool for the analysis and the understanding of the mammalian circadian oscillator. Forward and reverse…”
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Reciprocal regulation of carbon monoxide metabolism and the circadian clock
Published in Nature structural & molecular biology (01-01-2017)“…Genetic and biochemical assays reveal that carbon monoxide produced by heme catabolism influences circadian rhythm in mammals by altering the activity of…”
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Regulation of Monoamine Oxidase A by Circadian-Clock Components Implies Clock Influence on Mood
Published in Current biology (06-05-2008)“…The circadian clock has been implicated in addiction and several forms of depression [1, 2], indicating interactions between the circadian and the reward…”
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Perfect timing: Epigenetic regulation of the circadian clock
Published in FEBS letters (20-05-2011)“…► Reversible histone modifications accompany circadian transcription. ► In particular histone methylation can maintain a repressive state. ► The modifying…”
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Klf15 Orchestrates Circadian Nitrogen Homeostasis
Published in Cell metabolism (07-03-2012)“…Diurnal variation in nitrogen homeostasis is observed across phylogeny. But whether these are endogenous rhythms, and if so, molecular mechanisms that link…”
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Lack of Food Anticipation in Per2 Mutant Mice
Published in Current biology (24-10-2006)“…Predicting time of food availability is key for survival in most animals. Under restricted feeding conditions, this prediction is manifested in anticipatory…”
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Physical Interaction between Cyclin-Dependent Kinase 5 (CDK5) and Clock Factors Affects the Circadian Rhythmicity in Peripheral Oscillators
Published in Clocks & Sleep (Online) (09-03-2022)“…Circadian rhythms are self-sustained oscillators with a period of 24 h that is based on the output of transcriptional and post-translational feedback loops…”
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Distinct Roles of DBHS Family Members in the Circadian Transcriptional Feedback Loop
Published in Molecular and Cellular Biology (01-11-2012)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Flexible phase adjustment of circadian albumin D site-binding protein (DBP) gene expression by CRYPTOCHROME1
Published in Genes & development (15-06-2010)“…The albumin D site-binding protein (DBP) governs circadian transcription of a number of hepatic detoxification and metabolic enzymes prior to the activity…”
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Impact of the circadian clock on the aging process
Published in Frontiers in neurology (06-03-2015)“…The increase of life expectancy and the decline of biological functions with advancing age are impending obstacles for our society. In general, age-related…”
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PERsuading nuclear receptors to dance the circadian rhythm
Published in Cell cycle (Georgetown, Tex.) (01-07-2010)“…The recurring light/dark cycle that has a period length of about 24 hours has been internalized in various organisms in the form of a circadian clock. This…”
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