Search Results - "Ripper, Justin"

Euodenine A: A Small-Molecule Agonist of Human TLR4 by Neve, Juliette E, Wijesekera, Hasanthi P, Duffy, Sandra, Jenkins, Ian D, Ripper, Justin A, Teague, Simon J, Campitelli, Marc, Garavelas, Agatha, Nikolakopoulos, George, Le, Phuc V, de A. Leone, Priscila, Pham, Ngoc B, Shelton, Philip, Fraser, Neil, Carroll, Anthony R, Avery, Vicky M, McCrae, Christopher, Williams, Nicola, Quinn, Ronald J

“…A small-molecule natural product, euodenine A (1), was identified as an agonist of the human TLR4 receptor. Euodenine A was isolated from the leaves of Euodia…”
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Efficient N-Demethylation of Opiate Alkaloids Using a Modified Nonclassical Polonovski Reaction by McCamley, Kristy, Ripper, Justin A, Singer, Robert D, Scammells, Peter J

“…A modified Polonovski reaction has been employed to N-demethylate several opiate alkaloids in moderate to high yield. This method provides an alternative to…”
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Synthesis of Four Novel Natural Product Inspired Scaffolds for Drug Discovery by Jenkins, Ian D, Lacrampe, Fabienne, Ripper, Justin, Alcaraz, Lilian, Van Le, Phuc, Nikolakopoulos, George, de Almeida Leone, Priscila, White, Rodney H, Quinn, Ronald J

“…Inspired by the novel spiro structures of a number of bioactive natural products such as the histrionicotoxins, a series of novel spiro scaffolds have been…”
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Photochemical N-demethylation of alkaloids by Ripper, Justin A., Tiekink, Edward R.T., Scammells, Peter J.

“…Certain alkaloids were observed to undergo N-demethylation processes under photochemical conditions. Tropine, acetyltropine, tropinone, and atropine were…”
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Abstract 4029: BL-011256 is a novel VEGFR3 selective inhibitor, which suppresses tumor lymphatics and lymph node metastasis in an animal model of melanoma by Leske, Annabell, Foitzik, Richard, Beaumont, Donna, Bentley, John, Bergman, Ylva, Brown, Chloe, Camerino, Michelle, Charman, Susan, Choi, Neil, Silva, Melanie D., Chung, Matthew, Falk, Hendrik, Ganame, Danny, Gregg, Alison, Grusovin, Julian, Harvey, Andrew, Hemley, Catherine, Holmes, Ian, Huff, Belinda, Inglis, Daniel, Kersten, Wilhelmus, Lavranos, Tina, Lessene, Romina, Lunniss, Gillian, Monahan, Brendon, Morrow, Benjamin, Nikac, Marica, Nikolakopoulos, George, Paul, Dharam, Peat, Tom, Ripper, Justin, Scherer, Michaela, Stupple, Paul, White, Karen, Street, Ian, Kremmidiotis, Gabriel

“…The role of VEGFR3 in lymphangiogenesis has been well established. Targeting VEGFR3 has been shown to curtail tumor progression mediated via lymphatic…”
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Synthesis of 5-methylfuro[3,2- c]quinolin-4(5 H)-one via palladium-catalysed cyclisation of N-(2-iodophenyl)- N-methyl-3-furamide by Lindahl, Karl-Fredrik, Carroll, Anthony, Quinn, Ronald J., Ripper, Justin A.

“…A new method for the synthesis of 5-methylfuro[3,2- c]quinolin-4(5 H)-one has been developed and the palladium-catalysed cyclisation step has been shown to…”
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Carbene induced rearrangement products from two furoquinolinone scaffolds by Lindahl, Karl-Fredrik, Carroll, Anthony, Quinn, Ronald J., Ripper, Justin A.

“…Novel double CH‐insertion and rearrangement products (5, 6, and 7) were isolated from treatment of 1 or 2 with dimethyl diazomalonate (3) under…”
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