Search Results - "Rippe, K."

GRUU-Net: Integrated convolutional and gated recurrent neural network for cell segmentation by Wollmann, T., Gunkel, M., Chung, I., Erfle, H., Rippe, K., Rohr, K.

“…•Integration of CNN and gated RNN over multiple scales•Introduction of normalized focal loss for momentum based optimizers.•Provision of insights on how our…”
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Pan-mutant-IDH1 inhibitor BAY1436032 is highly effective against human IDH1 mutant acute myeloid leukemia in vivo by Chaturvedi, A, Herbst, L, Pusch, S, Klett, L, Goparaju, R, Stichel, D, Kaulfuss, S, Panknin, O, Zimmermann, K, Toschi, L, Neuhaus, R, Haegebarth, A, Rehwinkel, H, Hess-Stumpp, H, Bauser, M, Bochtler, T, Struys, E A, Sharma, A, Bakkali, A, Geffers, R, Araujo-Cruz, M M, Thol, F, Gabdoulline, R, Ganser, A, Ho, A D, von Deimling, A, Rippe, K, Heuser, M, Krämer, A

“…Neomorphic mutations in isocitrate dehydrogenase 1 ( IDH1 ) are frequently found in several human cancer types including acute myeloid leukemia (AML) and lead…”
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TRANSCRIPTIONAL AND GENOMIC INTRA‐TUMOR HETEROGENEITY DRIVES SUBCLONE SPECIFIC DRUG RESPONSES IN DIFFUSE LARGE B CELL LYMPHOMA by Roider, T., Frauhammer, F., Seufert, J., Bordas, M., Stolarczyk, M., Rabe, S., Malm, J., Bruch, P., Hundemer, M., Rippe, K., Goeppert, B., Seiffert, M., Brors, B., Mechtersheimer, G., Müller‐Tidow, C., Fröhling, S., Schlesner, M., Huber, W., Anders, S., Dietrich, S.

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Ethical aspects of the fluoridation of water, salt, and milk by Rippe, K P

“…The article discusses two ethical aspects of the fluoridation of water, salt, and milk. First, it considers whether fluoridation contradicts the right of…”
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Superhelix dimensions of a 1868 base pair plasmid determined by scanning force microscopy in air and in aqueous solution by Rippe, Karsten, Mücke, Norbert, Langowski, Jörg

“…We have used scanning force microscopy (SFM) to study the conformation of a 1868 base pair plasmid (p1868) in its open circular form and at a superhelical…”
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Making contacts on a nucleic acid polymer by Rippe, Karsten

“…The interaction of proteins bound at distant sites on a nucleic acid chain plays an important role in many molecular biological processes. Contact between the…”
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Alternating d(G‐A) sequences form a parallel‐stranded DNA homoduplex by Rippe, K., Fritsch, V., Westhof, E., Jovin, T.M.

“…The oligonucleotides d[(G‐A)7G] and d[(G‐A)12G] self‐associate under physiological conditions (10 mM MgCl2, neutral pH) into a stable double‐helical structure…”
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DNA binding and oligomerization of NtrC studied by fluorescence anisotropy and fluorescence correlation spectroscopy by Sevenich, Franz W., Langowski, Jörg, Rippe, Karsten, Weiss, Verena

“…Fluorescence anisotropy and fluorescence correlation spectroscopy measurements of rhodamine-labeled DNA oligonucleotide duplexes have been used to determine…”
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Interspecies crosses: aspects of animal protection by Kamber, M Geiser, Steiger, A, Aus der Au, C, Baertschi, B, Bondolfi, A, Brenner, A, Bürki, K, Durrer, H, Guztwiller, A, Heiniger, B, Hummler, E, Jakob, S, Kuehnle, K, Lanzrein, B, Ledermann, B, Leuthold, W, Matter, B, Reiderer, B, Rippe, K P, Stadler, B, Tinner, M, Wannier, Th

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Capturing Chromosome Conformation by Dekker, Job, Rippe, Karsten, Dekker, Martijn, Kleckner, Nancy

“…We describe an approach to detect the frequency of interaction between any two genomic loci. Generation of a matrix of interaction frequencies between sites on…”
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469 Epigenomic characterization of non-melanoma skin cancer by Rodríguez Paredes, M., Solé Boldo, L., Raddatz, G., Gutekunst, J., Liberio, M., Mallm, J., Rippe, K., Lonsdorf, A.S., Lyko, F.

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Parallel-stranded duplex DNA by Rippe, K, Jovin, T M

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Histone acetylation increases chromatin accessibility by Görisch, Sabine M, Wachsmuth, Malte, Tóth, Katalin Fejes, Lichter, Peter, Rippe, Karsten

“…In eukaryotes, the interaction of DNA with proteins and supramolecular complexes involved in gene expression is controlled by the dynamic organization of…”
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Structure-function relationships in the Bvg and Evg two-component phosphorelay systems by Bantscheff, M., Perraud, A.-L., Bock, A., Rippe, K., Weiss, V., Glocker, M., Gross, R.

“…The unorthodox two-component phosphorelay systems BvgAS and EvgAS of Bordetella pertussis and E. coli, respectively, are suitable model systems to investigate…”
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The hydrogen-bonding structure in parallel-stranded duplex DNA is reverse Watson-Crick by Otto, C, Thomas, G. A, Rippe, K, Jovin, T. M, Peticolas, Werner L

“…Raman spectra of the parallel-stranded duplex formed from the deoxyoligonucleotides 5'-d-[(A)10TAATTTTAAATATTT]-3' (D1) and 5'-d[(T)10ATTAAAATTTATAAA]-3' (D2)…”
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Bayesian joint super-resolution, deconvolution, and denoising of images with Poisson-Gaussian noise by Gao, Q., Eck, S., Matthias, J., Chung, I., Engelhardt, J., Rippe, K., Rohr, K.

“…For images degraded by significant noise with mixed Poisson-Gaussian (PG) statistics, deconvolution or denoising methods generally do not perform well if they…”
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Comparison of segmentation methods for tissue microscopy images of glioblastoma cells by Baltissen, D., Wollmann, T., Gunkel, M., Chung, I., Erfle, H., Rippe, K., Rohr, K.

“…Segmentation of cell nuclei is crucial for analyzing microscopy image data and understanding cellular processes. We performed a comparison of different…”
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Simultaneous Binding of Two DNA Duplexes to the NtrC−Enhancer Complex Studied by Two-Color Fluorescence Cross-Correlation Spectroscopy by Rippe, Karsten

“…The transcription activator protein NtrC (nitrogen regulatory protein C, also termed NRI) can catalyze the transition of Escherichia coli RNA polymerase…”
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C13 TRANSLATIONAL RESEARCH IN ASTHMA: Asthma Development In Early Childhood Is Associated With Enhancer Reprogramming by Trump, S, Klos, M, Gu, L, Bauer, T, Ishaque, N, Thurmann, L, Bieg, M, Bauer, M, Gu, Z, Borte, M, Mallm, J-P, Roder, S, Herrmann, C, Rippe, K, Lehmann, I, Eils, R

“…Rational: Enhancers are important transcriptional regulatory elements and their deregulation might be an important factor in pathophysiological processes of…”
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Calculating transcription factor binding maps for chromatin by TEIF, Vladimir B, RIPPE, Karsten

“…Current high-throughput experiments already generate enough data for retrieving the DNA sequence-dependent binding affinities of transcription factors (TF) and…”
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