Search Results - "Riou, Philippe"
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Long-term water quality in the lower Seine: Lessons learned over 4 decades of monitoring
Published in Environmental science & policy (01-04-2016)“…•Evolution of the water quality in the lower Seine over the last 40 years.•Impact of human activities and water management practices on nutrient…”
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Large-scale patterns of river inputs in southwestern Europe: seasonal and interannual variations and potential eutrophication effects at the coastal zone
Published in Biogeochemistry (01-05-2013)“…We provide data on nutrient export for 28 rivers in southwestern Europe and analyze long-term changes in the context of anthropogenic pressures and regulation…”
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3
Cdc42 promotes transendothelial migration of cancer cells through β1 integrin
Published in The Journal of cell biology (12-11-2012)“…Cancer cells interact with endothelial cells during the process of metastatic spreading. Here, we use a small interfering RNA screen targeting Rho GTPases in…”
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Rnd proteins: Multifunctional regulators of the cytoskeleton and cell cycle progression
Published in BioEssays (01-11-2010)“…Rnd3/RhoE has two distinct functions, regulating the actin cytoskeleton and cell proliferation. This might explain why its expression is often altered in…”
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Proneural Transcription Factors Regulate Different Steps of Cortical Neuron Migration through Rnd-Mediated Inhibition of RhoA Signaling
Published in Neuron (Cambridge, Mass.) (24-03-2011)“…Little is known of the intracellular machinery that controls the motility of newborn neurons. We have previously shown that the proneural protein Neurog2…”
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An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration
Published in Nature communications (27-02-2014)“…A transcriptional programme initiated by the proneural factors Neurog2 and Ascl1 controls successive steps of neurogenesis in the embryonic cerebral cortex…”
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aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization
Published in Developmental cell (22-08-2016)“…Atypical protein kinase C (aPKC) is a key apical-basal polarity determinant and Par complex component. It is recruited by Par3/Baz (Bazooka in Drosophila) into…”
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Assessing the water quality of the Seine land-to-sea continuum for three agro-food system scenarios
Published in Frontiers in Marine Science (28-10-2022)“…Three scenarios for the future of the French agro-food system were specified for the territory draining into the Seine Bight, comprising Paris megacity and the…”
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Evaluating ecosystem-level anthropogenic impacts in a stressed transitional environment: The case of the Seine estuary
Published in Ecological indicators (01-02-2016)“…•Six food web models of the Seine estuary, before and after harbour extension works.•Ecological network analysis indices showed regression of stability in…”
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Annual Phytoplankton Primary Production Estimation in a Temperate Estuary by Coupling PAM and Carbon Incorporation Methods
Published in Estuaries and coasts (01-07-2018)“…Phytoplankton primary production varies considerably with environmental parameters especially in dynamic ecosystems like estuaries. The aim of this study was…”
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Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes
Published in Biochemical journal (15-04-2013)“…The aPKC [atypical PKC (protein kinase C)] isoforms ι and ζ play crucial roles in the formation and maintenance of cell polarity and represent attractive…”
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Coastal Ocean and Nearshore Observation: A French Case Study
Published in Frontiers in Marine Science (25-06-2019)“…To understand and predict the physical, chemical, and biological processes at play in coastal and nearshore marine areas requires an integrated,…”
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Managing the Agri-Food System of Watersheds to Combat Coastal Eutrophication: A Land-to-Sea Modelling Approach to the French Coastal English Channel
Published in Geosciences (Basel) (01-10-2019)“…The continental coastal waters of the Eastern Channel, from Normandy to Hauts-de-France, are subject to the major influence of unbalanced nutrient inputs from…”
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Rnd3 induces stress fibres in endothelial cells through RhoB
Published in Biology open (15-02-2013)“…Rnd proteins are atypical Rho family proteins that do not hydrolyse GTP and are instead regulated by expression levels and post-translational modifications…”
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Comment déterminer l'exposition aux changements climatiques des zones de production forestière française ?Méthodologie utilisée dans le projet ESPERENSE pour cibler les zones d’intérêt pour l’installation d’essais de comparaison d’essences et de provenances
Published in Revue forestière française (22-07-2022)“…Les dernières observations de dépérissements et l’analyse de leurs causes tendent à confirmer la vulnérabilité de certaines des principales essences…”
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Generation and Modulation of Hepatocellular Carcinoma Circulating Cells: A New Experimental Model
Published in The Journal of surgical research (01-12-2008)“…Background To establish a new experimental model of human hepatocellular carcinoma by orthotopic implantation of tumoral cells with its subsequent removal, to…”
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Investigation in Liver Tissues and Cell Lines of the Transcription of 13 Genes Mapping to the 16q24 Region That Are Frequently Deleted in Hepatocellular Carcinoma
Published in Clinical cancer research (01-10-2002)“…Many studies have associated chromosomal deletions in the 16q24 region with human cancers, including hepatocellular carcinoma. A more limited region around the…”
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Modeling the biogeochemical functioning of the Seine estuary and its coastal zone: Export, retention, and transformations
Published in Limnology and oceanography (01-05-2019)“…The model ECO-MARS3D, successfully applied thus far to coastal ecosystems, has been extended to encompass the Seine estuary up to Poses, at the limit between…”
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Atypical Protein Kinase Cι as a human oncogene and therapeutic target
Published in Biochemical pharmacology (01-03-2014)“…Protein kinase inhibitors represent a major class of targeted therapeutics that has made a positive impact on treatment of cancer and other disease…”
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Rnd3-induced cell rounding requires interaction with Plexin-B2
Published in Journal of cell science (01-11-2016)“…Rnd proteins are atypical members of the Rho GTPase family that induce actin cytoskeletal reorganization and cell rounding. Rnd proteins have been reported to…”
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