Search Results - "Riordan, J. F."
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Nuclear Translocation of Angiogenin in Proliferating Endothelial Cells is Essential to Its Angiogenic Activity
Published in Proceedings of the National Academy of Sciences - PNAS (01-03-1994)“…The intracellular pathway of human angiogenin in calf pulmonary artery endothelial (CPAE) cells has been studied by immunofluorescence microscopy…”
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Angiogenin Activates Erk1/2 in Human Umbilical Vein Endothelial Cells
Published in Biochemical and biophysical research communications (14-09-2001)“…Angiogenin is a potent angiogenic factor that binds to endothelial cells and is endocytosed and rapidly translocated to the nucleus where it is concentrated in…”
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Organogenesis and angiogenin
Published in Cellular and molecular life sciences : CMLS (01-10-1997)“…Our search for an angiogenesis-inducing factor in culture medium conditioned by human colon adenocarcinoma cells (HT-29) was inspired by the 'organizer'…”
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Crystal Structure of Human Angiogenin Reveals the Structural Basis for Its Functional Divergence from Ribonuclease
Published in Proceedings of the National Academy of Sciences - PNAS (12-04-1994)“…Angiogenin, a potent inducer of neovascularization, is the only angiogenic molecule known to exhibit ribonucleolytic activity. Its overall structure, as…”
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Actin is a Binding Protein for Angiogenin
Published in Proceedings of the National Academy of Sciences - PNAS (15-02-1993)“…The 42-kDa angiogenin binding protein isolated previously has been purified to electrophoretic homogeneity. It has been identified as a member of the actin…”
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Molecular Cloning of Human Testicular Angiotensin-Converting Enzyme: The Testis Isozyme is Identical to the C-Terminal Half of Endothelial Angiotensin-Converting Enzyme
Published in Proceedings of the National Academy of Sciences - PNAS (01-10-1989)“…Angiotensin-converting enzyme (ACE; EC 3.4.15.1) is a zinc-containing dipeptidyl carboxypeptidase widely distributed in mammalian tissues and is thought to…”
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Membrane proteins with soluble counterparts: role of proteolysis in the release of transmembrane proteins
Published in Biochemistry (Easton) (01-10-1991)“…Many proteins lead a dual existence as both membrane-bound and soluble isoforms. One that has recently received a great deal of attention is the amyloid…”
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Angiogenin Promotes Invasiveness of Cultured Endothelial Cells by Stimulation of Cell-Associated Proteolytic Activities
Published in Proceedings of the National Academy of Sciences - PNAS (06-12-1994)“…Angiogenin, a potent inducer of neovascularization in the chicken chorioallantoic membrane and rabbit cornea, promotes endothelial cell invasion of Matrigel…”
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Angiotensin-converting enzyme: new concepts concerning its biological role
Published in Biochemistry (Easton) (27-06-1989)“…Angiotensin-converting enzyme (ACE, EC 3.4.15.1) is a zinc metalloprotease catalyzing the hydrolysis of carboxy-terminal dipeptides from oligopeptide…”
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Role of Glutamine-117 in the Ribonucleolytic Activity of Human Angiogenin
Published in Proceedings of the National Academy of Sciences - PNAS (12-04-1994)“…The crystal structure of human angiogenin (reported in the preceding paper in this issue) reveals that the site that corresponds to the pyrimidine binding site…”
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Actin is a Surface Component of Calf Pulmonary Artery Endothelial Cells in Culture
Published in Proceedings of the National Academy of Sciences - PNAS (01-05-1993)“…An angiogenin binding protein isolated previously from endothelial cells has been shown to be a member of the actin family. Calf pulmonary artery endothelial…”
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Spontaneous Solubilization of Membrane-Bound Human Testis Angiotensin- Converting Enzyme Expressed in Chinese Hamster Ovary Cells
Published in Proceedings of the National Academy of Sciences - PNAS (01-02-1991)“…The testis isozyme of angiotensin-converting enzyme (ACE; EC 3.4.15.1) is a membrane-bound protein that, apart from the first 35 N-terminal residues, is…”
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Angiogenin enhances actin acceleration of plasminogen activation
Published in Biochemical and biophysical research communications (15-12-1993)“…Angiogenin interacts with actin to form a complex, which like actin itself, can accelerate plasmin generation by tissue plasminogen activator (tPA). In…”
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Ribonucleolytic Activity of Angiogenin: Essential Histidine, Lysine, and Arginine Residues
Published in Proceedings of the National Academy of Sciences - PNAS (01-12-1987)“…The homology of angiogenin and pancreatic RNase A provides a compelling reason to systematically compare the characteristics of the two proteins using the…”
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Isolation and characterization of angiogenin, an angiogenic protein from human carcinoma cells
Published in Biochemistry (Easton) (01-09-1985)“…The first human tumor derived protein with in vivo angiogenic activity to be obtained in pure form has been isolated from serum-free supernatants of an…”
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An Angiogenin-Binding Protein from Endothelial Cells
Published in Proceedings of the National Academy of Sciences - PNAS (15-03-1991)“…A 42-kDa bovine protein that binds bovine angiogenin [angiogenin binding protein (AngBP)] has been identified as a dissociable cell-surface component of calf…”
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Characteristic ribonucleolytic activity of human angiogenin
Published in Biochemistry (Easton) (01-06-1986)“…Angiogenin, a blood vessel inducing protein isolated from a human tumor cell line, has been found to exhibit ribonucleolytic activity. It catalyzes the…”
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Angiogenin Abolishes Cell-Free Protein Synthesis by Specific Ribonucleolytic Inactivation of Ribosomes
Published in Proceedings of the National Academy of Sciences - PNAS (01-12-1987)“…Angiogenin is a potent inhibitor of cell-free protein synthesis. When incubated with rabbit reticulocyte lysate at a concentration of 40-60 nM, it completely…”
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Alteration of the enzymatic specificity of human angiogenin by site-directed mutagenesis
Published in Biochemistry (Easton) (09-03-1993)“…The molecular basis for the enzymatic specificity of human angiogenin has been investigated by site-directed mutagenesis of Thr-44, Glu-108, and…”
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