Search Results - "Riordan, Hugh D."

Vitamin C pharmacokinetics: Implications for oral and intravenous use by PADAYATTY, Sebastian J, HE SUN, YAOHUI WANG, RIORDAN, Hugh D, HEWITT, Stephen M, KATZ, Arie, WESLEY, Robert A, LEVINE, Mark

“…Vitamin C at high concentrations is toxic to cancer cells in vitro. Early clinical studies of vitamin C in patients with terminal cancer suggested clinical…”
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Orthomolecular Oncology Review: Ascorbic Acid and Cancer 25 Years Later by González, Michael J., Miranda-Massari, Jorge R., Mora, Edna M., Guzmán, Angelik, Riordan, Neil H., Riordan, Hugh D., Casciari, Joseph J., Jackson, James A., Román-Franco, Angel

“…The effect of ascorbic acid on cancer has been a subject of great controversy. This is a follow-up review of the 1979 article by Cameron, Pauling, and…”
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Changes in USDA food composition data for 43 garden crops, 1950 to 1999 by Davis, D.R, Epp, M.D, Riordan, H.D

“…OBJECTIVES: To evaluate possible changes in USDA nutrient content data for 43 garden crops between 1950 and 1999 and consider their potential causes. METHODS:…”
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Activation of Raf1 and the ERK pathway in response to l-ascorbic acid in acute myeloid leukemia cells by Park, Seyeon, Park, Chan H., Hahm, Eun-Ryeong, Kim, Kihyun, Kimler, Bruce F., Lee, Sook J., Park, Hye K., Lee, Se-Hoon, Kim, Won S., Jung, Chul W., Park, Keunchil, Riordan, Hugh D., Lee, Je-Ho

“…l-ascorbic acid (LAA) shows cytotoxicity and induces apoptosis of malignant cells in vitro, but the mechanisms by which such effects occur have not been…”
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Intravenously administered vitamin C as cancer therapy: three cases by Padayatty, Sebastian J, Riordan, Hugh D, Hewitt, Stephen M, Katz, Arie, Hoffer, L John, Levine, Mark

“…Early clinical studies showed that high-dose vitamin C, given by intravenous and oral routes, may improve symptoms and prolong life in patients with terminal…”
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l-Ascorbic acid induces apoptosis in acute myeloid leukemia cells via hydrogen peroxide-mediated mechanisms by Park, Seyeon, Han, Seong-Su, Park, Chan H, Hahm, Eun-Ryeong, Lee, Sook J, Park, Hye K, Lee, Se-Hoon, Kim, Won S, Jung, Chul Won, Park, Keunchil, Riordan, Hugh D, Kimler, Bruce F, Kim, Kihyun, Lee, Je-Ho

“…l-Ascorbic acid (LAA) is being investigated clinically for the treatment of patients with acute myeloid leukemia (AML) based on the observed effects of LAA on…”
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A pilot clinical study of continuous intravenous ascorbate in terminal cancer patients by Riordan, Hugh D, Casciari, Joseph J, González, Michael J, Riordan, Neil H, Miranda-Massari, Jorge R, Taylor, Paul, Jackson, James A

“…Case studies suggest that vitamin C, given intravenously at doses of 10-100 grams/day can improve patient well being and in some cases, reduce tumor size…”
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Vitamin C Pharmacokinetics after Continuous Infusion in a Patient with Prostate Cancer by Duconge, Jorge, Miranda-Massari, Jorge R, González, Michael J, Taylor, Paul R, Riordan, Hugh D, Riordan, Neil H, Casciari, Joseph J, Alliston, Kevin

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L-ascorbic acid represses constitutive activation of NF-κB and COX-2 expression in human acute myeloid leukemia, HL-60 by Han, Seong-Su, Kim, Kihyun, Hahm, Eun-Ryeong, Lee, Sook J., Surh, Young-Joon, Park, Hye K., Kim, Won S., Jung, Chul W., Lee, Mark H., Park, Keunchil, Yang, Jung-Hyun, Yoon, Sung-Soo, Riordan, Neil H., Riordan, Hugh D., Kimler, Bruce F., Park, Chan H., Lee, Je-Ho, Park, Seyeon

“…There is increasing evidence that l‐ascorbic acid (LAA) is selectively toxic to some types of cancer cells at pharmacological concentrations, functioning as a…”
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Cell membrane fatty acid composition differs between normal and malignant cell lines by Meng, Xialong, Riordan, Neil H, Riordan, Hugh D, Mikirova, Nina, Jackson, James, González, Michael J, Miranda-Massari, Jorge R, Mora, Edna, Trinidad Castillo, Waleska

“…Twenty-eight fatty acids (C8:0 to C24:l n-9) were measured by gas chromatography in four normal cell lines (C3H / 10T1 / 2, CCD-18Co, CCD-25SK and CCD-37Lu)…”
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Effects of high dose ascorbate administration on L-10 tumor growth in guinea pigs by Casciari, Joseph J, Riordan, Hugh D, Miranda-Massari, Jorge R, Gonzalez, Michael J

“…Sodium ascorbate is preferentially toxic to tumor cells at high concentrations. It has not been established, however, whether sufficient intra-tumor ascorbate…”
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Intravenous vitamin C as a chemotherapy agent: a report on clinical cases by Riordan, Hugh D, Riordan, Neil H, Jackson, James A, Casciari, Joseph J, Hunninghake, Ron, González, Michael J, Mora, Edna M, Miranda-Massari, Jorge R, Rosario, Norberto, Rivera, Alfredo

“…A series of seven cases are presented in which intravenous vitamin C has been used as antineoplastic agent in the treatment of different types of cancers. The…”
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Intravenous ascorbic acid: protocol for its application and use by Riordan, Hugh D, Hunninghake, Ronald B, Riordan, Neil H, Jackson, James J, Meng, Xiaolong, Taylor, Paul, Casciari, Joseph J, González, Michael J, Miranda-Massari, Jorge R, Mora, Edna M, Rosario, Norberto, Rivera, Alfredo

“…High dose intravenous(i.v.) ascorbic acid (AA) has been used as therapy for infectious disease from bacterial and viral origin and adjuvant therapy for cancer…”
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Erythrocyte membrane fatty acid composition in cancer patients by Mikirova, Nina, Riordan, Hugh D, Jackson, James A, Wong, Kelly, Miranda-Massari, Jorge R, Gonzalez, Michael J

“…Essential fatty acids (EFA) have an important role in complex metabolic reactions. The metabolism of essential polyunsaturated fatty acids (PUFA) appears to be…”
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Effects of a high molecular mass Convolvulus arvensis extract on tumor growth and angiogenesis by Meng, Xiao Long, Riordan, Neil H, Casciari, Joseph J, Zhu, Yan, Zhong, Jie, González, Michael J, Miranda-Massari, Jorge R, Riordan, Hugh D

“…Plant materials represent promising sources of anti-cancer agents. We developed and tested a novel extract from the ubiquitous plant Convolvulus arvensis…”
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Intravenous ascorbic acid as a treatment for severe jellyfish stings by Kumar, Selva, Miranda-Massari, Jorge R, Gonzalez, Michael J, Riordan, Hugh D

“…We report a case of jellyfish envenomation in a 39 year old male. He was stung extensively on both lower limbs by an unidentified jellyfish. This occurred in…”
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Inhibition of human breast carcinoma cell proliferation by ascorbate and copper by González, Michael J, Mora, Edna M, Miranda-Massari, Jorge R, Matta, Jaime, Riordan, Hugh D, Riordan, Neil H

“…We tested the effect of different concentrations of ascorbic acid (AA), 50, 100, 250 mg/500 mg/dL) with copper sulfate (CS), 10 mg/dL) on human breast…”
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Orthomolecular oncology: a mechanistic view of intravenous ascorbate's chemotherapeutic activity by González, Michael J, Miranda-Massari, Jorge R, Mora, Edna M, Jiménez, Ivonne Z, Matos, María Isabel, Riordan, Hugh D, Casciari, Joseph J, Riordan, Neil H, Rodríguez, Marielys, Guzmán, Angelik

“…The effect of vitamin C in cancer has been a subject of great controversy; mainly because of the inconsistent results obtained by oral intakes of ascorbate…”
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L-ascorbic acid represses constitutive activation of NF-kappaB and COX-2 expression in human acute myeloid leukemia, HL-60 by Han, Seong-Su, Kim, Kihyun, Hahm, Eun-Ryeong, Lee, Sook J, Surh, Young-Joon, Park, Hye K, Kim, Won S, Jung, Chul W, Lee, Mark H, Park, Keunchil, Yang, Jung-Hyun, Yoon, Sung-Soo, Riordan, Neil H, Riordan, Hugh D, Kimler, Bruce F, Park, Chan H, Lee, Je-Ho, Park, Seyeon

“…There is increasing evidence that L-ascorbic acid (LAA) is selectively toxic to some types of cancer cells at pharmacological concentrations, functioning as a…”
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Vitamin C pharmacokinetics after continuous infusion in a patient with prostate cancer by Duconge, Jorge, Miranda-Massari, Jorge R, González, Michael J, Taylor, Paul R, Riordan, Hugh D, Riordan, Neil H, Casciari, Joseph J, Alliston, Kevin

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