Search Results - "Rioja, I"
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BET protein inhibition shows efficacy against JAK2V617F-driven neoplasms
Published in Leukemia (01-01-2014)“…Small molecule inhibition of the BET family of proteins, which bind acetylated lysines within histones, has been shown to have a marked therapeutic benefit in…”
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Joint cytokine quantification in two rodent arthritis models: kinetics of expression, correlation of mRNA and protein levels and response to prednisolone treatment
Published in Clinical and experimental immunology (01-07-2004)“…SUMMARY Biomarker quantification in disease tissues from animal models of rheumatoid arthritis (RA) can help to provide insights into the mechanisms of action…”
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Protective Effect of PEG 35 000 Da on Renal Cells: Paradoxical Activation of JNK Signaling Pathway During Cold Storage
Published in American journal of transplantation (01-07-2006)“…Polyethylene glycol (PEG), a high‐molecular weight colloid, is added to preservation solutions in order to decrease cold‐ and ischemia‐induced injuries of the…”
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Giant Vascular Eccrine Spiradenoma
Published in Actas dermo-sifiliográficas (English ed.) (01-12-2015)Get full text
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In vitro target validation and in vivo efficacy of p38 MAP kinase inhibition in established chronic collagen-induced arthritis model: a pre-clinical study
Published in Clinical and experimental rheumatology (01-03-2010)“…The aim of the present study was to determine the in vivo efficacy of p38 mitogen-activated protein kinase (MAPK) inhibitors, namely GW856553X and GSK678361,…”
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Giant Vascular Eccrine Spiradenoma
Published in Actas dermo-sifiliográficas (English ed.) (01-12-2015)Get full text
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7
Inhibition of Leukocyte Functions by the Alkaloid Isaindigotone from Isatis indigotica and Some New Synthetic Derivatives
Published in Journal of natural products (Washington, D.C.) (01-10-2001)“…The alkaloid isaindigotone (1a) and seven derivatives have been synthesized to study their influence on several leukocyte functions and the generation of…”
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Gene expression profiles in the rat streptococcal cell wall-induced arthritis model identified using microarray analysis
Published in Arthritis research & therapy (01-01-2005)“…Experimental arthritis models are considered valuable tools for delineating mechanisms of inflammation and autoimmune phenomena. Use of microarray-based…”
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Solid-Phase Synthesis and Inhibitory Effects of Some Pyrido[1,2-c]pyrimidine Derivatives on Leukocyte Functions and Experimental Inflammation
Published in Journal of medicinal chemistry (15-03-2001)“…A number of pyrido[1,2-c]pyrimidines bearing a nitrogen, oxygen, or sulfur functionality at C-1 were synthesized on solid-phase using the iminophosphorane…”
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Solid-phase synthesis and inhibitory effects of some pyrido[1,2-c]pyrimidine derivatives on leukocyte formations and experimental inflammation
Published in Journal of medicinal chemistry (15-03-2001)“…A number of pyrido[1,2-c]pyrimidines bearing a nitrogen, oxygen, or sulfur functionality at C-1 were synthesized on solid-phase using the iminophosphorane…”
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Synthesis and Pharmacological Evaluation of Some 8-Cyanopyrido[3‘,2‘:4,5]thieno[3,2-d]triazine Derivatives as Inhibitors of Nitric Oxide and Eicosanoid Biosynthesis
Published in Journal of medicinal chemistry (04-11-1999)“…A series of 8-cyanopyrido[3‘,2‘:4,5]thieno[3,2-d]-1,2,3-triazines, substituted at C-4 and C-7, were synthesized and evaluated as nitric oxide and prostaglandin…”
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An anti-inflammatory ditriazine inhibiting leukocyte functions and expression of inducible nitric oxide synthase and cyclo-oxygenase-2
Published in European journal of pharmacology (26-05-2000)“…A ditriazine derivative (4,10-dichloropyrido[5,6:4,5]thieno[3,2- d′:3,2- d]-1,2,3-ditriazine (DTD)) inhibited neutrophil functions, including degranulation,…”
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Acute abdomen following COVID-19 vaccination: a systematic review
Published in Clinical and experimental vaccine research (Seoul) (2024)“…Purpose: Conduct a systematic review of case reports and case series regarding the development of acute abdomen following coronavirus disease 2019 (COVID-19)…”
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Infrastructure and sectoral output along the road to development
Published in International economic journal (01-03-2004)“…Public infrastructure is one of the foundations for economic growth. Empirical research has found that public infrastructure can have different effects in…”
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