Search Results - "Ringnalda, Femke C.A.S."
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Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair
Published in eLife (29-05-2018)“…The CRISPR-Cas9 targeted nuclease technology allows the insertion of genetic modifications with single base-pair precision. The preference of mammalian cells…”
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Sequential intravital imaging reveals in vivo dynamics of pancreatic tissue transplanted under the kidney capsule in mice
Published in Diabetologia (01-11-2016)“…Aims/hypothesis Dynamic processes in pancreatic tissue are difficult to study. We aimed to develop an intravital imaging method to longitudinally examine…”
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In vitro Generation of CRISPR-Cas9 Complexes with Covalently Bound Repair Templates for Genome Editing in Mammalian Cells
Published in Bio-protocol (05-01-2019)“…The CRISPR-Cas9 system is a powerful genome-editing tool that promises application for gene editing therapies. The Cas9 nuclease is directed to the DNA by a…”
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