Search Results - "Ringeling, Francisca Rojas"

Leukemia-induced dysfunctional TIM-3+CD4+ bone marrow T cells increase risk of relapse in pediatric B-precursor ALL patients by Blaeschke, Franziska, Willier, Semjon, Stenger, Dana, Lepenies, Mareike, Horstmann, Martin A., Escherich, Gabriele, Zimmermann, Martin, Rojas Ringeling, Francisca, Canzar, Stefan, Kaeuferle, Theresa, Rohlfs, Meino, Binder, Vera, Klein, Christoph, Feuchtinger, Tobias

“…Interaction of malignancies with tissue-specific immune cells has gained interest for prognosis and intervention of emerging immunotherapies. We analyzed bone…”
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Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders by Wang, Xinyuan, Ye, Fei, Wen, Zhexing, Guo, Ziyuan, Yu, Chuan, Huang, Wei-Kai, Rojas Ringeling, Francisca, Su, Yijing, Zheng, Wei, Zhou, Guomin, Christian, Kimberly M., Song, Hongjun, Zhang, Mingjie, Ming, Guo-li

“…Psychiatric disorders are a collection of heterogeneous mental disorders arising from a contribution of genetic and environmental insults, many of which…”
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Alternative splicing regulates stochastic NLRP3 activity by Hoss, Florian, Mueller, James L., Rojas Ringeling, Francisca, Rodriguez-Alcazar, Juan F., Brinkschulte, Rebecca, Seifert, Gerald, Stahl, Rainer, Broderick, Lori, Putnam, Chris D., Kolodner, Richard D., Canzar, Stefan, Geyer, Matthias, Hoffman, Hal M., Latz, Eicke

“…Leucine-rich repeat (LRR) domains are evolutionarily conserved in proteins that function in development and immunity. Here we report strict exonic modularity…”
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Linear-time cluster ensembles of large-scale single-cell RNA-seq and multimodal data by Do, Van Hoan, Rojas Ringeling, Francisca, Canzar, Stefan

“…A fundamental task in single-cell RNA-seq (scRNA-seq) analysis is the identification of transcriptionally distinct groups of cells. Numerous methods have been…”
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A Common Embryonic Origin of Stem Cells Drives Developmental and Adult Neurogenesis by Berg, Daniel A., Su, Yijing, Jimenez-Cyrus, Dennisse, Patel, Aneek, Huang, Nancy, Morizet, David, Lee, Stephanie, Shah, Reeti, Ringeling, Francisca Rojas, Jain, Rajan, Epstein, Jonathan A., Wu, Qing-Feng, Canzar, Stefan, Ming, Guo-Li, Song, Hongjun, Bond, Allison M.

“…New neurons arise from quiescent adult neural progenitors throughout life in specific regions of the mammalian brain. Little is known about the embryonic…”
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Zika-Virus-Encoded NS2A Disrupts Mammalian Cortical Neurogenesis by Degrading Adherens Junction Proteins by Yoon, Ki-Jun, Song, Guang, Qian, Xuyu, Pan, Jianbo, Xu, Dan, Rho, Hee-Sool, Kim, Nam-Shik, Habela, Christa, Zheng, Lily, Jacob, Fadi, Zhang, Feiran, Lee, Emily M., Huang, Wei-Kai, Ringeling, Francisca Rojas, Vissers, Caroline, Li, Cui, Yuan, Ling, Kang, Koeun, Kim, Sunghan, Yeo, Junghoon, Cheng, Yichen, Liu, Sheng, Wen, Zhexing, Qin, Cheng-Feng, Wu, Qingfeng, Christian, Kimberly M., Tang, Hengli, Jin, Peng, Xu, Zhiheng, Qian, Jiang, Zhu, Heng, Song, Hongjun, Ming, Guo-li

“…Zika virus (ZIKV) directly infects neural progenitors and impairs their proliferation. How ZIKV interacts with the host molecular machinery to impact…”
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Counting pseudoalignments to novel splicing events by Borozan, Luka, Rojas Ringeling, Francisca, Kao, Shao-Yen, Nikonova, Elena, Monteagudo-Mesas, Pablo, Matijević, Domagoj, Spletter, Maria L, Canzar, Stefan

“…Abstract Motivation Alternative splicing (AS) of introns from pre-mRNA produces diverse sets of transcripts across cell types and tissues, but is also…”
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Partitioning RNAs by length improves transcriptome reconstruction from short-read RNA-seq data by Ringeling, Francisca Rojas, Chakraborty, Shounak, Vissers, Caroline, Reiman, Derek, Patel, Akshay M., Lee, Ki-Heon, Hong, Ari, Park, Chan-Woo, Reska, Tim, Gagneur, Julien, Chang, Hyeshik, Spletter, Maria L., Yoon, Ki-Jun, Ming, Guo-li, Song, Hongjun, Canzar, Stefan

“…The accuracy of methods for assembling transcripts from short-read RNA sequencing data is limited by the lack of long-range information. Here we introduce…”
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FAM111A Mutations Result in Hypoparathyroidism and Impaired Skeletal Development by Unger, Sheila, Górna, Maria W., Le Béchec, Antony, Do Vale-Pereira, Sonia, Bedeschi, Maria Francesca, Geiberger, Stefan, Grigelioniene, Giedre, Horemuzova, Eva, Lalatta, Faustina, Lausch, Ekkehart, Magnani, Cinzia, Nampoothiri, Sheela, Nishimura, Gen, Petrella, Duccio, Rojas-Ringeling, Francisca, Utsunomiya, Akari, Zabel, Bernhard, Pradervand, Sylvain, Harshman, Keith, Campos-Xavier, Belinda, Bonafé, Luisa, Superti-Furga, Giulio, Stevenson, Brian, Superti-Furga, Andrea

“…Kenny-Caffey syndrome (KCS) and the similar but more severe osteocraniostenosis (OCS) are genetic conditions characterized by impaired skeletal development…”
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Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation by Yoon, Ki-Jun, Ringeling, Francisca Rojas, Vissers, Caroline, Jacob, Fadi, Pokrass, Michael, Jimenez-Cyrus, Dennisse, Su, Yijing, Kim, Nam-Shik, Zhu, Yunhua, Zheng, Lily, Kim, Sunghan, Wang, Xinyuan, Doré, Louis C., Jin, Peng, Regot, Sergi, Zhuang, Xiaoxi, Canzar, Stefan, He, Chuan, Ming, Guo-li, Song, Hongjun

“…N6-methyladenosine (m6A), installed by the Mettl3/Mettl14 methyltransferase complex, is the most prevalent internal mRNA modification. Whether m6A regulates…”
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CYFIP1 Dosages Exhibit Divergent Behavioral Impact via Diametric Regulation of NMDA Receptor Complex Translation in Mouse Models of Psychiatric Disorders by Kim, Nam-Shik, Ringeling, Francisca Rojas, Zhou, Ying, Nguyen, Ha Nam, Temme, Stephanie J., Lin, Yu-Ting, Eacker, Stephen, Dawson, Valina L., Dawson, Ted M., Xiao, Bo, Hsu, Kuei-sen, Canzar, Stefan, Li, Weidong, Worley, Paul, Christian, Kimberly M., Yoon, Ki-Jun, Song, Hongjun, Ming, Guo-li

“…Gene dosage imbalance caused by copy number variations (CNVs) is a prominent contributor to brain disorders. In particular, 15q11.2 CNV duplications and…”
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FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export by Edens, Brittany M., Vissers, Caroline, Su, Jing, Arumugam, Saravanan, Xu, Zhaofa, Shi, Han, Miller, Nimrod, Rojas Ringeling, Francisca, Ming, Guo-li, He, Chuan, Song, Hongjun, Ma, Yongchao C.

“…N6-methyladenosine (m6A) modification of mRNA is emerging as a vital mechanism regulating RNA function. Here, we show that fragile X mental retardation protein…”
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FMRP Modulates Neural Differentiation through m 6 A-Dependent mRNA Nuclear Export by Edens, Brittany M, Vissers, Caroline, Su, Jing, Arumugam, Saravanan, Xu, Zhaofa, Shi, Han, Miller, Nimrod, Rojas Ringeling, Francisca, Ming, Guo-Li, He, Chuan, Song, Hongjun, Ma, Yongchao C

“…N -methyladenosine (m A) modification of mRNA is emerging as a vital mechanism regulating RNA function. Here, we show that fragile X mental retardation protein…”
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Temporal Control of Mammalian Cortical Neurogenesis by m 6 A Methylation by Yoon, Ki-Jun, Ringeling, Francisca Rojas, Vissers, Caroline, Jacob, Fadi, Pokrass, Michael, Jimenez-Cyrus, Dennisse, Su, Yijing, Kim, Nam-Shik, Zhu, Yunhua, Zheng, Lily, Kim, Sunghan, Wang, Xinyuan, Doré, Louis C, Jin, Peng, Regot, Sergi, Zhuang, Xiaoxi, Canzar, Stefan, He, Chuan, Ming, Guo-Li, Song, Hongjun

“…N -methyladenosine (m A), installed by the Mettl3/Mettl14 methyltransferase complex, is the most prevalent internal mRNA modification. Whether m A regulates…”
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