Search Results - "Ring, Christopher J.A."
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Recent advances in the manipulation of murine gene expression and its utility for the study of human neurological disease
Published in Biochimica et biophysica acta (01-10-2010)“…Transgenic mouse models have vastly contributed to our knowledge of the genetic and molecular pathways underlying the pathogenesis of neurological disorders…”
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Cytolytic viruses as potential anti-cancer agents
Published in Journal of general virology (01-03-2002)“…Gene Interference, Glaxo SmithKline Research & Development, Medicines Research Centre, Gunnels Wood Road, Stevenage, Herts SG1 2NY, UK 1 Author for…”
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Adenoviral-mediated Cre expression effectively suppresses GlyT1 binding in the thalamic area of GlyT1 conditional knock-out mice
Published in Journal of neuroscience methods (30-11-2010)“…▶ We investigated the use of adenoviral vector-mediated Cre expression to mediate localized gene modulation in the specific thalamic area. ▶ This technology…”
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The use of DNA viruses as vectors for gene therapy
Published in Gene therapy (01-11-1994)“…The need for efficient transfer of potentially therapeutic genes to defined cell populations has stimulated the development of vectors based on viruses. To…”
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Functional studies of signaling pathways in peri-implantation development of the mouse embryo by RNAi
Published in BMC developmental biology (28-12-2005)“…Studies of gene function in the mouse have relied mainly on gene targeting via homologous recombination. However, this approach is difficult to apply in…”
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Recombinant respiratory syncytial virus lacking secreted glycoprotein G is attenuated, non-pathogenic but induces protective immunity
Published in Microbes and infection (01-10-2004)“…Respiratory syncytial virus (RSV) causes intense pulmonary inflammatory responses in some infected infants. The surface attachment protein ‘G’ of RSV has…”
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The opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domain
Published in Molecular and Cellular Biology (01-10-1994)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Improvement of HCV genome detection with "short" PCR products
Published in The Lancet (British edition) (07-12-1991)Get more information
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Transactivation of the human papilloma virus 16 octamer motif by the octamer binding protein Oct-2 requires both the N and C terminal activation domains
Published in Nucleic acids research (25-09-1993)“…The upstream regulatory region (URR) of the human papillomaviruses HPV16 and 18 contains a sequence with a seven out of eight base match to the consensus…”
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