Search Results - "Rinella, Mary"
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Nonalcoholic Fatty Liver Disease: A Systematic Review
Published in JAMA : the journal of the American Medical Association (09-06-2015)“…IMPORTANCE: Nonalcoholic fatty liver disease and its subtype nonalcoholic steatohepatitis affect approximately 30% and 5%, respectively, of the US population…”
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Nonalcoholic Fatty Liver Disease 2020: The State of the Disease
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2020)“…Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease, with a worldwide prevalence of 25%. In the United States, NAFLD and its subtype,…”
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The globalization of nonalcoholic fatty liver disease: Prevalence and impact on world health
Published in Hepatology (Baltimore, Md.) (01-07-2016)Get full text
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Pegozafermin for NASH — A Sprint to Start a Marathon
Published in The New England journal of medicine (14-09-2023)“…Pharmacotherapy in patients with nonalcoholic steatohepatitis (NASH) has been a frustrating endeavor, with failures outnumbering successes by some margin, even…”
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AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease
Published in Hepatology (Baltimore, Md.) (01-05-2023)Get full text
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From NAFLD to MASLD: updated naming and diagnosis criteria for fatty liver disease
Published in Journal of lipid research (01-01-2024)Get full text
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Management of NAFLD: a stage-based approach
Published in Nature reviews. Gastroenterology & hepatology (01-04-2016)“…Key Points NAFLD is the most common cause of liver disease, affecting 30% of the US population; however, the goals of treatment differ based on stage of…”
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From NAFLD to MAFLD: Implications of a Premature Change in Terminology
Published in Hepatology (Baltimore, Md.) (01-03-2021)“…Despite the substantial gains in our understanding of NAFLD/NASH over the past 2 decades, there has been some dissatisfaction with the terminology…”
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Mechanisms of NAFLD development and therapeutic strategies
Published in Nature medicine (01-07-2018)“…There has been a rise in the prevalence of nonalcoholic fatty liver disease (NAFLD), paralleling a worldwide increase in diabetes and metabolic syndrome…”
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A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis
Published in The New England journal of medicine (08-02-2024)“…Resmetirom is a selective agonist of THR-β. In adults with nonalcoholic steatohepatitis and fibrosis, daily resmetirom (80 mg or 100 mg) was superior to…”
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Steatotic liver disease: a new name to reflect the combined role of alcohol and metabolic dysfunction
Published in Nature medicine (01-04-2024)“…Steatotic liver disease is part of a revised nomenclature to replace the term fatty liver disease, but this should also drive forward innovation in research,…”
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Nonalcoholic Fatty Liver Disease, Diabetes, Obesity, and Hepatocellular Carcinoma
Published in Clinics in liver disease (01-05-2015)“…Diabetes and obesity are associated with nonalcoholic fatty liver disease (NAFLD) and an increased incidence of hepatocellular carcinoma (HCC). NAFLD is the…”
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Pioneering the path to NASH biomarker approval
Published in Nature medicine (01-10-2023)“…Despite an urgent need, approved and clinically usable biomarkers for non-alcoholic steatohepatitis (NASH) remain elusive — but a new study moves the field…”
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STELLAR 3 and STELLAR 4: Lessons from the fall of Icarus
Published in Journal of hepatology (01-07-2020)Get full text
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American Association of Clinical Endocrinology Clinical Practice Guideline for the Diagnosis and Management of Nonalcoholic Fatty Liver Disease in Primary Care and Endocrinology Clinical Settings: Co-Sponsored by the American Association for the Study of Liver Diseases (AASLD)
Published in Endocrine practice (01-05-2022)“…To provide evidence-based recommendations regarding the diagnosis and management of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis…”
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Metabolic dysfunction-associated steatotic liver disease: Update and impact of new nomenclature on the American Association for the Study of Liver Diseases practice guidance on nonalcoholic fatty liver disease
Published in Hepatology (Baltimore, Md.) (01-05-2024)“…This commentary discusses how clinicians and various stakeholders can utilize the recently published American Association for the Study of Liver Diseases…”
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Systematic review with meta‐analysis: risk of hepatocellular carcinoma in non‐alcoholic steatohepatitis without cirrhosis compared to other liver diseases
Published in Alimentary pharmacology & therapeutics (01-10-2018)“…Summary Background Given the lack of long‐term prospective studies, it is challenging for clinicians to make informed decisions about screening and treatment…”
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Fatty Liver Disease: Diagnosis and Stratification
Published in Annual review of medicine (27-01-2022)“…Nonalcoholic fatty liver disease (NAFLD) is a major public health crisis affecting approximately 25% of the world's population. The spectrum of NAFLD ranges…”
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A multisociety Delphi consensus statement on new fatty liver disease nomenclature
Published in Journal of hepatology (01-12-2023)“…The principal limitations of the terms NAFLD and NASH are the reliance on exclusionary confounder terms and the use of potentially stigmatising language. This…”
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