Search Results - "Rindflesch, Thomas C"
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Assigning factuality values to semantic relations extracted from biomedical research literature
Published in PloS one (05-07-2017)“…Biomedical knowledge claims are often expressed as hypotheses, speculations, or opinions, rather than explicit facts (propositions). Much biomedical text…”
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Constructing a semantic predication gold standard from the biomedical literature
Published in BMC bioinformatics (20-12-2011)“…Semantic relations increasingly underpin biomedical text mining and knowledge discovery applications. The success of such practical applications crucially…”
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Large-scale structure of a network of co-occurring MeSH terms: statistical analysis of macroscopic properties
Published in PloS one (09-07-2014)“…Concept associations can be represented by a network that consists of a set of nodes representing concepts and a set of edges representing their relationships…”
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Augmenting microarray data with literature-based knowledge to enhance gene regulatory network inference
Published in PLoS computational biology (01-06-2014)“…Gene regulatory networks are a crucial aspect of systems biology in describing molecular mechanisms of the cell. Various computational models rely on random…”
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SemMedDB: a PubMed-scale repository of biomedical semantic predications
Published in Bioinformatics (01-12-2012)“…Effective access to the vast biomedical knowledge present in the scientific literature is challenging. Semantic relations are increasingly used in knowledge…”
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Investigating the role of interleukin-1 beta and glutamate in inflammatory bowel disease and epilepsy using discovery browsing
Published in Journal of biomedical semantics (27-12-2018)“…Structured electronic health records are a rich resource for identifying novel correlations, such as co-morbidities and adverse drug reactions. For drug…”
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Natural language processing: State of the art and prospects for significant progress, a workshop sponsored by the National Library of Medicine
Published in Journal of biomedical informatics (01-10-2013)“…[Display omitted] •We report on a natural language workshop sponsored by the National Library of Medicine.•We summarize the current state of the art in…”
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Biomedical question answering using semantic relations
Published in BMC bioinformatics (16-01-2015)“…The proliferation of the scientific literature in the field of biomedicine makes it difficult to keep abreast of current knowledge, even for domain experts…”
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Networks of neuroinjury semantic predications to identify biomarkers for mild traumatic brain injury
Published in Journal of biomedical semantics (18-05-2015)“…Mild traumatic brain injury (mTBI) has high prevalence in the military, among athletes, and in the general population worldwide (largely due to falls)…”
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Context-driven automatic subgraph creation for literature-based discovery
Published in Journal of biomedical informatics (01-04-2015)“…[Display omitted] •Implicit and explicit semantics to capture context can be effective for LBD.•Multifaceted subgraphs can be captured using clustering based…”
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Smart and Connected Health [Guest editors' introduction]
Published in IEEE intelligent systems (01-05-2014)“…Computing plays an important role in all aspects of achieving and maintaining health and well-being. Exploiting health information technology for decreasing…”
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Exploiting Literature-derived Knowledge and Semantics to Identify Potential Prostate Cancer Drugs
Published in Cancer informatics (01-01-2014)“…In this study, we report on the performance of an automated approach to discovery of potential prostate cancer drugs from the biomedical literature. We used…”
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Argument-predicate distance as a filter for enhancing precision in extracting predications on the genetic etiology of disease
Published in BMC bioinformatics (08-06-2006)“…Genomic functional information is valuable for biomedical research. However, such information frequently needs to be extracted from the scientific literature…”
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Sortal anaphora resolution to enhance relation extraction from biomedical literature
Published in BMC bioinformatics (14-04-2016)“…Entity coreference is common in biomedical literature and it can affect text understanding systems that rely on accurate identification of named entities, such…”
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Clustering cliques for graph-based summarization of the biomedical research literature
Published in BMC bioinformatics (07-06-2013)“…Graph-based notions are increasingly used in biomedical data mining and knowledge discovery tasks. In this paper, we present a clique-clustering method to…”
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Identifying plausible adverse drug reactions using knowledge extracted from the literature
Published in Journal of biomedical informatics (01-12-2014)“…[Display omitted] •We evaluate PSI-based identification of relationships between drugs and ADRs.•PSI can incorporate relations and concepts and infer reasoning…”
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The interaction of domain knowledge and linguistic structure in natural language processing: interpreting hypernymic propositions in biomedical text
Published in Journal of biomedical informatics (01-12-2003)“…Interpretation of semantic propositions in free-text documents such as MEDLINE citations would provide valuable support for biomedical applications, and…”
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Discovering discovery patterns with predication-based Semantic Indexing
Published in Journal of biomedical informatics (01-12-2012)“…[Display omitted] ► PSI represents concepts and relations in hyperdimensional space. ► PSI is used to infer discovery patterns from known therapeutic…”
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Framing serendipitous information-seeking behavior for facilitating literature-based discovery: A proposed model
Published in Journal of the Association for Information Science and Technology (01-03-2014)“…Several researchers have studied serendipitous knowledge discovery in information‐seeking behavior. Electronic data in the form of semantic predications have a…”
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Using semantic predications to uncover drug–drug interactions in clinical data
Published in Journal of biomedical informatics (01-06-2014)“…[Display omitted] •Discovery of drug–drug interactions in patient data using literature knowledge.•Structured knowledge extracted from MEDLINE and stored in…”
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