Search Results - "Rincón, Jaimar"

Role of angiotensin II in the brain inflammatory events during experimental diabetes in rats by Vargas, Renata, Rincón, Jaimar, Pedreañez, Adriana, Viera, Ninoska, Hernández-Fonseca, Juan P, Peña, Caterina, Mosquera, Jesús

“…Abstract Hyperglycemia during diabetes is one of the causes of encephalopathy. However, diabetes causes chronic inflammatory complications and among them is…”
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Experimental depression induces renal oxidative stress in rats by Pedreañez, Adriana, Arcaya, José Luis, Carrizo, Edgardo, Rincón, Jaimar, Viera, Ninoska, Peña, Caterina, Vargas, Renata, Mosquera, Jesús

“…Abstract Depression has been associated to inflammatory and oxidative events. Previous report has shown renal oxidative stress in patients with depression. In…”
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Mycophenolate mofetil prevents salt-sensitive hypertension resulting from nitric oxide synthesis inhibition by Quiroz, Y, Pons, H, Gordon, K L, Rincón, J, Chávez, M, Parra, G, Herrera-Acosta, J, Gómez-Garre, D, Largo, R, Egido, J, Johnson, R J, Rodríguez-Iturbe, B

“…Recent studies have suggested that subtle microvascular and tubulointerstitial injury in the kidney can cause salt-sensitive hypertension. To test this…”
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Proinflammatory role of angiotensin II in a rat nephrosis model induced by adriamycin by Muñoz, Maydelin, Rincón, Jaimar, Pedreañez, Adriana, Viera, Ninoska, Hernández-Fonseca, Juan P, Mosquera, Jesús

“…Introduction: Nephrotic syndrome induced by adriamycin (ADR) is an experimental model of glomerulosclerosis in humans. The AT1 receptor for angiotensin II (Ang…”
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Overexpression of HGF transgene attenuates renal inflammatory mediators, Na+-ATPase activity and hypertension in spontaneously hypertensive rats by Romero-Vásquez, Freddy, Chávez, Maribel, Pérez, Mariela, Arcaya, José L., García, Alberto J., Rincón, Jaimar, Rodríguez-Iturbe, Bernardo

“…Renal inflammation and oxidative stress are constantly present in experimental hypertension. Since the spontaneously hypertensive rat (SHR) has reduced levels…”
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Immunopathology of chronic critical illness in sepsis survivors: Role of abnormal myelopoiesis by Rincon, Jaimar C., Efron, Philip A., Moldawer, Lyle L.

“…Sepsis remains the single most common cause of mortality and morbidity in hospitalized patients requiring intensive care. Although earlier detection and…”
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Examining bile acids in pediatric sepsis - a step in the right direction by Hernandez-Rios, Miguel, Rincon, Jaimar C, Efron, Philip A, Larson, Shawn D

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Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis by Hollen, McKenzie K, Stortz, Julie A, Darden, Dijoia, Dirain, Marvin L, Nacionales, Dina C, Hawkins, Russell B, Cox, Michael C, Lopez, Maria-Cecilia, Rincon, Jaimar C, Ungaro, Ricardo, Wang, Zhongkai, Wu, Quran, Brumback, Babette, Gauthier, Marie-Pierre L, Kladde, Michael, Leeuwenburgh, Christiaan, Segal, Mark, Bihorac, Azra, Brakenridge, Scott, Moore, Frederick A, Baker, Henry V, Mohr, Alicia M, Moldawer, Lyle L, Efron, Philip A

“…Sepsis is an increasingly significant challenge throughout the world as one of the major causes of patient morbidity and mortality. Central to the host…”
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T‐Cell Activation and LPS: A Dangerous Duo for Organ Dysfunction by Kerr, Austin W, Efron, Philip A, Larson, Shawn D, Rincon, Jaimar C

“…Lipopolysaccharide (LPS), one of the main components of cell membranes in gram‐negative bacteria, is commonly used to promote inflammation‐induced organ…”
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Pro-inflammatory role of angiotensin II in mercuric chloride-induced nephropathy in rats by Peña, Caterina, Hernández-Fonseca, Juan P, Rincón, Jaimar, Pedreañez, Adriana, Viera, Ninoska, Mosquera, Jesús

“…Mercuric chloride (HgCl₂), which induces kidney toxicity, constitutes a potential threat to human health. In addition to direct toxic effects, kidney…”
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Cecal Slurry Injection in Neonatal and Adult Mice by Rincon, Jaimar C, Efron, Philip A, Moldawer, Lyle L, Larson, Shawn D

“…Studying the pathophysiology of sepsis still requires animal models, and the mouse remains the most commonly used species. Here we discuss the "cecal slurry"…”
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Variables Influencing the Differential Host Response to Burns in Pediatric and Adult Patients by Barrios, Evan L., Polcz, Valerie E., Moldawer, Lyle L., Rincon, Jaimar C., Efron, Philip A., Larson, Shawn D.

“…Burn injury is a significant source of morbidity and mortality in the pediatric population. Although 40,000 pediatric patients in the United States are…”
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Forced swimming test decreases chemotactic responsiveness and expression of CD11a in rat monocytes by Briceño, Francisco, Arcaya, José Luis, Carrizo, Edgardo, Rincón, Jaimar, Mosquera, Jesús

“…Previous reports have shown that the depressive status in humans and experimental animals is associated with decreased immune response. Since monocyte…”
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Sepsis is associated with reduced spontaneous neutrophil migration velocity in human adults by Raymond, Steven L, Hawkins, Russell B, Stortz, Julie A, Murphy, Tyler J, Ungaro, Ricardo, Dirain, Marvin L, Nacionales, Dina C, Hollen, McKenzie K, Rincon, Jaimar C, Larson, Shawn D, Brakenridge, Scott C, Moore, Frederick A, Irimia, Daniel, Efron, Phil A, Moldawer, Lyle L

“…Sepsis is a common and deadly complication among trauma and surgical patients. Neutrophils must mobilize to the site of infection to initiate an immediate…”
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Impact of Early-Life Exposures to Infections, Antibiotics, and Vaccines on Perinatal and Long-term Health and Disease by Raymond, Steven L, Rincon, Jaimar C, Wynn, James L, Moldawer, Lyle L, Larson, Shawn D

“…Essentially, all neonates are exposed to infections, antibiotics, or vaccines early in their lives. This is especially true for those neonates born underweight…”
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Single-Cell RNA-seq of Human Myeloid-Derived Suppressor Cells in Late Sepsis Reveals Multiple Subsets With Unique Transcriptional Responses: A Pilot Study by Darden, Dijoia B., Bacher, Rhonda, Brusko, Maigan A., Knight, Parker, Hawkins, Russell B., Cox, Michael C., Dirain, Marvin L., Ungaro, Ricardo, Nacionales, Dina C., Rincon, Jaimar C., Gauthier, Marie-Pierre L., Kladde, Michael, Bihorac, Azra, Brusko, Todd M., Moore, Frederick A., Brakenridge, Scott C., Mohr, Alicia M., Moldawer, Lyle L., Efron, Philip A.

“…BACKGROUND:Increased circulating myeloid-derived suppressor cells (MDSCs) are independently associated with poor long-term clinical outcomes in sepsis. Studies…”
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Aluminum Adjuvant Improves Survival Via NLRP3 Inflammasome and Myeloid Non-Granulocytic Cells in a Murine Model of Neonatal Sepsis by Rincon, Jaimar C., Hawkins, Russell B., Hollen, Mckenzie, Nacionales, Dina C., Ungaro, Ricardo, Efron, Philip A., Moldawer, Lyle L., Larson, Shawn D.

“…ABSTRACTNeonatal sepsis leads to significant morbidity and mortality with the highest risk of death occurring in preterm (<37 weeks) and low birth weight (LBW;…”
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A Novel Single Cell RNA-seq Analysis of Non-Myeloid Circulating Cells in Late Sepsis by Darden, Dijoia B, Dong, Xiaoru, Brusko, Maigan A, Kelly, Lauren, Fenner, Brittany, Rincon, Jaimar C, Dirain, Marvin L, Ungaro, Ricardo, Nacionales, Dina C, Gauthier, Marie, Kladde, Michael, Brusko, Todd M, Bihorac, Azra, Moore, Frederick A, Loftus, Tyler, Bacher, Rhonda, Moldawer, Lyle L, Mohr, Alicia M, Efron, Philip A

“…With the successful implementation of the Surviving Sepsis Campaign guidelines, post-sepsis in-hospital mortality to sepsis continues to decrease. Those who…”
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TRAINED IMMUNITY: A POTENTIAL APPROACH FOR IMPROVING HOST IMMUNITY IN NEONATAL SEPSIS by Polcz, Valerie E., Rincon, Jaimar C., Hawkins, Russell B., Barrios, Evan L., Efron, Philip A., Moldawer, Lyle L., Larson, Shawn D.

“…Sepsis, a dysregulated host immune response to infection, is one of the leading causes of neonatal mortality worldwide. Improved understanding of the perinatal…”
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TRANSCRIPTOMIC DIFFERENCES IN PERIPHERAL MONOCYTE POPULATIONS IN SEPTIC PATIENTS BASED ON OUTCOME by Barrios, Evan L, Rincon, Jaimar C, Willis, Micah, Polcz, Valerie E, Leary, Jack R, Darden, Dijoia B, Balch, Jeremy A, Larson, Shawn D, Loftus, Tyler J, Mohr, Alicia M, Wallet, Shannon, Brusko, Maigan A, Balzano-Nogueira, Leandro, Cai, Guoshuai, Sharma, Ashish, Upchurch, Jr, Gilbert R, Kladde, Michael P, Mathews, Clayton E, Maile, Robert, Moldawer, Lyle L, Bacher, Rhonda, Efron, Philip A

“…Postsepsis early mortality is being replaced by survivors who experience either a rapid recovery and favorable hospital discharge or the development of chronic…”
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