Search Results - "Rimpelová, Silvie"

Na + /K + -ATPase Revisited: On Its Mechanism of Action, Role in Cancer, and Activity Modulation by Bejček, Jiří, Spiwok, Vojtěch, Kmoníčková, Eva, Rimpelová, Silvie

“…Maintenance of Na and K gradients across the cell plasma membrane is an essential process for mammalian cell survival. An enzyme responsible for this process,…”
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Vincristine in Combination Therapy of Cancer: Emerging Trends in Clinics by Škubník, Jan, Pavlíčková, Vladimíra Svobodová, Ruml, Tomáš, Rimpelová, Silvie

“…Treatment of blood malignancies and other cancer diseases has been mostly unfeasible, so far. Therefore, novel treatment regimens should be developed and the…”
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Autophagy in cancer resistance to paclitaxel: Development of combination strategies by Škubník, Jan, Svobodová Pavlíčková, Vladimíra, Ruml, Tomáš, Rimpelová, Silvie

“…Paclitaxel, a compound naturally occurring in yew, is a commonly used drug for the treatment of different types of cancer. Unfortunately, frequent cancer cell…”
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Mitotic Poisons in Research and Medicine by Škubník, Jan, Jurášek, Michal, Ruml, Tomáš, Rimpelová, Silvie

“…Cancer is one of the greatest challenges of the modern medicine. Although much effort has been made in the development of novel cancer therapeutics, it still…”
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Medicinal Use of Testosterone and Related Steroids Revisited by Tauchen, Jan, Jurášek, Michal, Huml, Lukáš, Rimpelová, Silvie

“…Testosterone derivatives and related compounds (such as anabolic-androgenic steroids-AAS) are frequently misused by athletes (both professional and amateur)…”
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Antibody Conjugated PLGA Nanocarriers and Superparmagnetic Nanoparticles for Targeted Delivery of Oxaliplatin to Cells from Colorectal Carcinoma by Zumaya, Alma Lucia Villela, Rimpelová, Silvie, Štějdířová, Markéta, Ulbrich, Pavel, Vilčáková, Jarmila, Hassouna, Fatima

“…Anti-CD133 monoclonal antibody (Ab)-conjugated poly(lactide-co-glycolide) (PLGA) nanocarriers, for the targeted delivery of oxaliplatin (OXA) and…”
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Repurposing Cardiac Glycosides: Drugs for Heart Failure Surmounting Viruses by Škubník, Jan, Bejček, Jiří, Pavlíčková, Vladimíra Svobodová, Rimpelová, Silvie

“…Drug repositioning is a successful approach in medicinal research. It significantly simplifies the long-term process of clinical drug evaluation, since the…”
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Current Perspectives on Taxanes: Focus on Their Bioactivity, Delivery and Combination Therapy by Škubník, Jan, Pavlíčková, Vladimíra, Ruml, Tomáš, Rimpelová, Silvie

“…Taxanes, mainly paclitaxel and docetaxel, the microtubule stabilizers, have been well known for being the first-line therapy for breast cancer for more than…”
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Cardiac Glycosides as Immune System Modulators by Škubník, Jan, Pavlíčková, Vladimíra, Rimpelová, Silvie

“…Cardiac glycosides (CGs) are natural steroid compounds occurring both in plants and animals. They are known for long as cardiotonic agents commonly used for…”
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Quo vadis Cardiac Glycoside Research? by Bejček, Jiří, Jurášek, Michal, Spiwok, Vojtěch, Rimpelová, Silvie

“…Cardiac glycosides (CGs), toxins well-known for numerous human and cattle poisoning, are natural compounds, the biosynthesis of which occurs in various plants…”
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Highly variable biological effects of statins on cancer, non-cancer, and stem cells in vitro by Gbelcová, Helena, Rimpelová, Silvie, Jariabková, Adriana, Macášek, Patrik, Priščáková, Petra, Ruml, Tomáš, Šáchová, Jana, Kubovčiak, Jan, Kolář, Michal, Vítek, Libor

“…Statins, the drugs used for the treatment of hypercholesterolemia, have come into the spotlight not only as chemoadjuvants, but also as potential stem cell…”
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Advances in the Determination of Anabolic-Androgenic Steroids: From Standard Practices to Tailor-Designed Multidisciplinary Approaches by Huml, Lukáš, Tauchen, Jan, Rimpelová, Silvie, Holubová, Barbora, Lapčík, Oldřich, Jurášek, Michal

“…Anabolic-androgenic steroids (AASs), a group of compounds frequently misused by athletes and, unfortunately, also by the general population, have lately…”
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Plasma-Activated Polydimethylsiloxane Microstructured Pattern with Collagen for Improved Myoblast Cell Guidance by Slepičková Kasálková, Nikola, Juřicová, Veronika, Fajstavr, Dominik, Frýdlová, Bára, Rimpelová, Silvie, Švorčík, Václav, Slepička, Petr

“…We focused on polydimethylsiloxane (PDMS) as a substrate for replication, micropatterning, and construction of biologically active surfaces. The novelty of…”
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Cell Behavior of Primary Fibroblasts and Osteoblasts on Plasma-Treated Fluorinated Polymer Coated with Honeycomb Polystyrene by Fajstavrová, Klára, Rimpelová, Silvie, Fajstavr, Dominik, Švorčík, Václav, Slepička, Petr

“…The development of new biocompatible polymer substrates is still of interest to many research teams. We aimed to combine a plasma treatment of fluorinated…”
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Honeycomb-patterned poly(L-lactic) acid on plasma-activated FEP as cell culture scaffold by Neznalová, Klára, Fajstavr, Dominik, Rimpelová, Silvie, Kasálková, Nikola Slepičková, Kolská, Zdeňka, Švorčík, Václav, Slepička, Petr

“…•Homogeneous honeycomb structure from PLLA was prepared on perfluorinated polymer.•Plasma activation improved the phase separation technique…”
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Comparison of Transcriptomic Profiles of MiaPaCa-2 Pancreatic Cancer Cells Treated with Different Statins by Rimpelová, Silvie, Kolář, Michal, Strnad, Hynek, Ruml, Tomáš, Vítek, Libor, Gbelcová, Helena

“…Statins have been widely used for the treatment of hypercholesterolemia due to their ability to inhibit HMG-CoA reductase, the rate-limiting enzyme of de novo…”
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Quo Vadis Advanced Prostate Cancer Therapy? Novel Treatment Perspectives and Possible Future Directions by Kvízová, Jana, Pavlíčková, Vladimíra, Kmoníčková, Eva, Ruml, Tomáš, Rimpelová, Silvie

“…Prostate cancer is a very common disease, which is, unfortunately, often the cause of many male deaths. This is underlined by the fact that the early stages of…”
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Intriguing Cytotoxicity of the Street Dissociative Anesthetic Methoxphenidine: Unexpected Impurities Spotted by Jurásek, Bronislav, Rimpelová, Silvie, Babor, Martin, Čejka, Jan, Bartůněk, Vilém, Kuchař, Martin

“…The black market for new psychoactive substances has been constantly evolving and the substances that appear on this market cause a considerable number of…”
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KrF Laser and Plasma Exposure of PDMS-Carbon Composite and Its Antibacterial Properties by Fajstavr, Dominik, Frýdlová, Bára, Rimpelová, Silvie, Kasálková, Nikola Slepičková, Sajdl, Petr, Švorčík, Václav, Slepička, Petr

“…A polydimethylsiloxane (PDMS) composite with multi-walled carbon nanotubes was successfully prepared. Composite foils were treated with both plasma and excimer…”
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Inhibition of Mitochondrial Metabolism Leads to Selective Eradication of Cells Adapted to Acidic Microenvironment by Koncošová, Martina, Vrzáčková, Nikola, Křížová, Ivana, Tomášová, Petra, Rimpelová, Silvie, Dvořák, Aleš, Vítek, Libor, Rumlová, Michaela, Ruml, Tomáš, Zelenka, Jaroslav

“…Metabolic transformation of cancer cells leads to the accumulation of lactate and significant acidification in the tumor microenvironment. Both lactate and…”
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